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Rexulti (Brexpiprazole)
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This is a prescription medication that’s used to treat specific mood and mental disorders. These include major depressive disorder, also known as depression, in adults as well as schizophrenia in those who are age 13 and up. It’s also used for treating the agitation that can happen with dementia from Alzheimer’s disease. Rexulti is in a class of drugs called atypical antipsychotics.
There is some question about how exactly it works on the brain. It’s believed that it treats a chemical imbalance in the brain by helping to balance specific natural chemicals found there. It’s thought that it changes the actions of both dopamine and serotonin, but the exact changes are still unknown. This medication is taken daily and not as needed for these disorders.
Rexulti Precautions and Warnings
When elderly patients take it for dementia-related problems, they have a higher risk of death. It shouldn’t be used for patients who have dementia-related psychosis but don’t have any agitation. In younger people, including young adults, this medication can raise the risk of having thoughts of suicide. Younger patients should be monitored for this problem. This drug is not to be used for pediatric patients who have depression.
If you’re allergic or hypersensitive to this medication or any of its ingredients, don’t take it. Hypersensitivity can cause swelling of the face, rash, and swelling of the lower layers of skin. Make sure your doctor knows your full medical history before taking this medication.
If you have any history of liver problems such as liver damage, tell your doctor. You may need a smaller dose of this medication for your safety. If you have a history of problems with your kidneys, such as kidney damage, make sure your doctor knows so that the appropriate dosage can be used.
If you currently have high triglyceride or high cholesterol levels, Rexulti may make this condition worse. Your doctor should check your lipid levels before you begin this medication. If you have a white blood cell count that’s too low, Rexulti can also make this worse. Your white cell count should be checked before starting this drug.
If you have a history of engaging in compulsive behaviors, Rexulti can make these behaviors worse. Compulsive behaviors can include binge eating, gambling, compulsive shopping, and more. If you have addictions or compulsive behaviors, talk to your doctor about them before you begin this medication.
This medication can make it harder for your body to regulate its temperature. If you already have a condition that does this, be sure to tell your doctor about it. If you have any seizure disorders such as epilepsy, talk to your doctor about it before you take Rexulti. It can make your risk of seizures higher.
Taking Rexulti can also result in low blood pressure. If you have any heart disease, you already have low blood pressure, or you have any issues with the electrical pathways of your heart, make sure your doctor knows. This medication may cause you to have dizziness and lower blood pressure when sitting up or standing up. It’s possible to faint from this issue. It’s also possible to fall because of the dizziness. If you already have a high risk of falling, this can make the risk higher.
If you’re diabetic, Rexulti can cause your blood sugar levels to increase. It may get so high that it’s dangerous. This can cause diabetic ketoacidosis or a diabetic coma in some patients. Rarely, it can be fatal. If you take Rexulti, make sure you monitor your blood sugar closely.
This medication may cause a patient to be sleepy, to have slower reflexes, and to experience delayed thinking. Before you drive or do other dangerous activities, make sure that you know how this medication affects you.
If you’re pregnant or may become pregnant, talk to your doctor about possible risk to the baby. It isn’t known whether it can harm babies, but there’s some evidence that it may cause withdrawal in babies once they’re born. If you want to breastfeed while on this medication, talk to your doctor about the possible risks.
Side Effects of Rexulti
There are mild effects that can be caused by Rexulti that may go away after a few weeks. If they linger or cause you trouble, let your doctor know. You may need a different medication or dosage.
Common Side Effects
Some of the common side effects of Rexulti include:
- Indigestion
- Constipation
- Restlessness
- Insomnia
- Sleepiness
- Fatigue
- Strange dreams
- Headache
- The common cold
- Diarrhea
- Anxiety
- Weight gain
Serious Side Effects
It’s also possible to get serious side effects from this medication, though this isn’t common. If these side effects happen, you need to either get in touch with your doctor or call for emergency medical care if you feel it’s needed. Serious side effects of Rexulti include:
- Increased triglyceride or cholesterol levels
- Reflexes or thinking that’s slowed down
- Symptoms of stroke: weakness or numbness in the legs, arms, or face, problems speaking, vision problems, confusion
- Symptoms of neuroleptic malignant syndrome: confusion, fever, sweating, rapid heart rate, rigid muscles, major blood pressure changes
- Uncontrolled body movements such as facial movement, waving arms, or blinking too often
- Symptoms of low white cell count: fevers and frequent infections
- Seizures
- Symptoms of high blood sugar: tiredness or weakness, being very hungry or thirsty, or urinating more than normal
- Low blood sugar causing dizziness when standing up
- Neck spasms that cause problems with swallowing
- Problems with cooling down after being in the heat or exercising
- Symptoms of an allergic reaction: rash, trouble breathing, swelling in the face, tongue, lips, or throat
Rexulti Drug Interactions
Make sure that your doctor knows everything you’re taking. This includes any herbal remedies or supplements.
There are medications that are not recommended for use along with Rexulti. Some of these medications include:
- Metoclopramide
- Bupropion
- Clarithromycin
- Dronedarone
- Erythromycin
- Fluoxetine
- Fluconazole
- Indinavir
- Ketoconazole
- Paroxetine
- Ritonavir
- Rifampin
- John’s wort
- Terbinafine
Strengths and Dosages of Rexulti
This medication is available only in tablet form. The strengths available include 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg. The specific dosage will depend on the reason for taking the medication, the patient’s age, how well they tolerate it, and how well it works for them.
| Rexulti tablets: | 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg |
Cost of Rexulti in the USA
The cost varies from pharmacy to pharmacy and with the strength of the dosage. For a three-month supply of 2 mg of Rexulti, it can cost as much as $4,700, depending on the strength of the tablets. There is a coupon card available from the manufacturer that can reduce this cost to as low as $15 a month for your prescription. The coupon card is free and available on the manufacturer’s website.
Why Is Rexulti So Expensive?
This was an expensive drug to bring to market, and it’s in demand. There is also no generic of this medication yet, so the manufacturer can charge as much as it chooses for it.
Rexulti Alternatives
FAQs for Rexulti
What is Rexulti used for?
It’s an atypical antipsychotic that is used to treat schizophrenia, major depressive disorder, and agitation in Alzheimer’s patients who have dementia.
How long does it take for Rexulti to start working?
It depends on the severity of the condition that’s being treated. The time varies from one person to another.
How long does Rexulti withdrawal last?
It can last for several weeks and include agitation, insomnia, anxiety, and other symptoms.
How long does Rexulti stay in your system?
It generally stays in the body for 18 to 19 days.
When will Rixulti go generic?
Many of the patents on this drug will expire in April of 2026. This can open the door to generics being sold.
How do you taper off Rexulti?
This should only be done under the advice of a doctor. The doctor will give you a plan for tapering down to smaller and smaller amounts and then taking them every other day and then every few days to wean the body from this medication.
What class of drug is Rexulti?
It’s in a class called atypical antipsychotics.
What happens when you stop taking Rexulti?
You may have withdrawal from this medication if you don’t taper off with medical monitoring. This can cause agitation, uncontrollable movements, anxiety, vomiting, muscle spasms, dizziness, diarrhea, nausea, and other symptoms.
How does Rexulti make you feel?
The results often depend on why the medication is taken. For those with depression, it can help improve mood. For those with schizophrenia, it can reduce symptoms of the disease. For those with dementia from Alzheimer’s, it can have a calming effect.
Does Rexulti cause weight gain?
Yes, it commonly causes weight gain. For those with depression, it was found in studies to cause weight gain for about 7% of the patients.
What happens if I missed a dose of Rexulti?
If it’s been a few hours since you missed your dose, go ahead and take the missing dose. However, if it’s been many hours, or it’s almost time for your next dose, skip the one that was missed.
What should I do if I have taken too much Rexulti?
You can call the poison control center to find out what to do based on the amount that you took. You can also contact your doctor right away to find out whether you need emergency medical assistance.
What should I avoid while taking Rexulti?
Avoid eating grapefruit or drinking grapefruit juice. Avoid drinking a large amount of alcohol. Don’t take any herbal supplements without checking with your doctor first.
Our Guarantee For Buying Rexulti From A Canadian Pharmacy Partner
At MyRx Outlet, we are committed to delivering safe, high-quality medications that you can trust. We adhere to strict regulations in every country we operate in, ensuring that your order is handled by a licensed Canadian pharmacy or a trusted partner overseas. Each medication has been legally approved by Health Canada or other respected authorities. To purchase Rexulti at a discounted rate, call 1-888-551-2467.
IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.
