Desipramine
Desipramine is a prescription tricyclic antidepressant used to treat depression. It is taken by mouth on a schedule set by a prescriber, and the dose is usually started low and adjusted over time.
We only dispense medications with a valid prescription from a licensed prescriber.
All prescriptions are reviewed and verified before dispensing. Orders may be delayed or declined if prescription details are missing, do not match the patient information on file, appear altered, or are expired. We may also refuse service if we believe an order is intended for resale or redistribution.
What You Receive
- Desipramine in sealed manufacturer packaging
- Personalized prescription instructions based on your prescriber’s directions
- Medication information leaflet provided by the manufacturer
- Itemized invoice detailing your order
- Rx Required
- Delivered Within 4-7 Days
- Medication From Canada
This page is for general information only and is not medical advice. For medical questions, please speak with your prescriber. See Sources & Methodology for how this information is reviewed and referenced.
Desipramine Key Facts
What Desipramine is
Desipramine is a tricyclic antidepressant (TCA). It is available as an oral tablet in multiple strengths.
What it’s used for
Desipramine is used to treat depression.
How it works
Desipramine affects brain chemicals involved in mood and emotional regulation. Its exact mechanism in depression is not fully understood, but it is classified as a tricyclic antidepressant.
Desipramine Safety Overview
Desipramine has important safety risks that require monitoring, especially early in treatment and during dose changes.
Desipramine Warnings & Precautions
Some risks relate to mood and behavior, and others relate to heart rhythm, blood pressure, and anticholinergic effects.
Do not use Desipramine if:
- You are taking an MAOI, or have taken an MAOI within the last 14 days
- You are in the acute recovery period after a myocardial infarction
- You have had a serious allergic reaction to desipramine
Key warnings to know
- Suicidal thoughts and behavior risk can increase in children, adolescents, and young adults, especially early in treatment
- Heart rhythm and blood pressure changes can occur, including fainting risk, and monitoring may be needed in higher risk patients
- Seizure and serotonin syndrome risk can increase with certain medicines
- Anticholinergic effects can worsen glaucoma, urinary retention, and constipation
Side Effects and When to Get Help
Side effects can be dose-related and may be more noticeable when starting or increasing the dose. Contact your prescriber if side effects are persistent, worsening, or interfering with daily life.
Possible side effects may include
- Drowsiness or dizziness
- Dry mouth or constipation
- Blurred vision
- Sweating
- Nausea
- Sleep changes
Get urgent help right away for
- Severe allergic reaction symptoms such as swelling, hives, or trouble breathing
- Fainting, severe dizziness, or a fast or irregular heartbeat
- Seizure
- Severe agitation, confusion, fever, or muscle stiffness
- New or rapidly worsening mood or behavior changes
Interactions
Desipramine has important interaction risks, especially with MAOIs and medicines that raise desipramine levels or increase heart rhythm and serotonin risks. A full medication review is important before starting, stopping, or changing any medicines.
Interactions you should discuss with your prescriber include
- MAOIs (including linezolid or IV methylene blue)
- CYP2D6 inhibitors that can raise desipramine levels
- Other antidepressants or serotonergic medicines
- Medicines that can affect heart rhythm
- Alcohol or other sedating medicines
Desipramine Drug Facts
| Category | Details |
|---|---|
| Brand Name | Desipramine |
| Drug Class | Tricyclic antidepressant (TCA) |
| Indication | Depression |
| Dosage Forms | Oral tablet |
| Strengths | 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg |
| Administration Timing | Once daily or divided doses; prescriber-titrated |
| Boxed Warning | Suicidality risk age ≤24; MAOI use; acute MI recovery; hypersensitivity |
| Storage | 20°C to 25°C (68°F to 77°F); protect from moisture |
| Missed Dose | Take next scheduled dose; do not double |
| Alternatives | Norpramin, Pamelor (nortriptyline), Tofranil (imipramine), Elavil (amitriptyline) |
Helpful Information
How To Buy Desipramine Online
1
Select Your Prescribed Desipramine Dosage & Strength
Choose the strength and quantity that matches your prescription, then add it to your cart. Orders are limited to a 90-day supply per fill.
2
Complete Checkout
Ensure your shipping and contact information is correct so your order can be processed without delays.
3
Submit Your Desipramine Prescription
Upload your prescription at checkout. If you need a transfer, provide your prescriber or current pharmacy details and we will request it on your behalf.
Prescription & Dispensing Standards
- Prescription required for all orders and reviewed for pharmacy and regulatory compliance
- Dispensed by licensed pharmacy partners
- Orders are held if information is missing, unclear, or does not match.
- No substitutions without prescriber approval, and no controlled substances.
Our Guarantee
At MyRx Outlet, we are committed to delivering safe, high-quality medications that you can trust. We adhere to strict regulations in every country we operate in, ensuring that your order is handled by a licensed Canadian pharmacy or a trusted partner overseas. Each medication has been legally approved by Health Canada or other respected authorities. To purchase Desipramine at a discounted rate, call 1-888-551-2467.
FAQs
What is Desipramine used for?
Desipramine is used to treat depression.
How should I take desipramine?
Take it exactly as prescribed. Dosing is individualized and may be adjusted over time.
How long does desipramine take to work?
Some people notice changes earlier, but full benefit can take several weeks. Keep taking it as directed and follow up with your prescriber.
What should I avoid while taking desipramine?
Avoid starting new medicines without checking first, especially MAOIs and other antidepressants, because serious interactions can occur.
What should I do if I miss a dose?
Take your next dose at the regular time. Do not take two doses at once.
Ordering & Prescription FAQs
Do I need a prescription?
Yes, a prescription is required. Refills depend on what your prescriber authorizes.
How do I submit my prescription?
You can upload it through our Upload Prescription page, email it to info@myrxoutlet.com, or fax it to 1-888-230-1245. If you need a prescription transfer, just let us know at checkout and include your pharmacy or prescriber contact details.
When is my payment processed?
Your payment is processed only after your prescription and order have been reviewed and approved by our licensed pharmacy team. Once everything is confirmed, we’ll process payment and prepare your order for shipping.
What happens if my prescription can’t be verified?
Your order may be placed on hold or declined if prescription details are missing, don’t match, are expired, or can’t be confirmed.
Sources
FDA Prescribing Information / Medication Guide, NORPRAMIN (desipramine hydrochloride tablets USP)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/014399s069lbl.pdf
DailyMed Drug Label, DESIPRAMINE HYDROCHLORIDE tablet
https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=7280f157-3fff-41c5-b3f4-510b8bacdaba