Rifadin is a type of antibiotic that contains rifampicin as its active ingredient. It’s often taken along with other medications for the treatment of tuberculosis. It is also used for treating leprosy. It can also be prescribed to patients to prevent them from developing infections resulting from Haemophilus Influenza Type B and meningococcal disease. It can help patients who have been exposed to bacterial meningitis to avoid developing the disease. This medication is in a medication class that’s called rifamycin antibiotics.

This medication works by stopping bacteria from growing. It interferes with bacteria’s ability to produce the genetic material for reproduction. It also kills bacteria. Rifadin only treats infections from bacteria and not from viruses or fungi. It’s essential to take your entire course of antibiotics and not stop when you start feeling better. This can lead to antibiotic-resistant infections that can be serious.

Rifadin Precautions and Warnings

Let your doctor know if you are allergic to this medication before it gets prescribed. Tell your doctor if you’re allergic to other rifamycin medications, including rifabutin. The medication will also have some inactive ingredients in it. Some of your allergies to other things could be in this medication as an inactive ingredient. Talk to the pharmacist about precisely what’s in it to find out.

Let your doctor know about your complete medical history. If you’ve had any liver problems such as hepatitis, you have used a lot of alcohol, you have diabetes, or you have an HIV infection, make sure your doctor knows right away before you take this medication. Don’t drink alcohol while you’re on this medication. It can increase your chances of getting liver disease.

If you’re going to take a live bacteria vaccine, such as the one for typhoid, wait until you’re finished with this medication to get it. Taking Rifadin can cause the vaccine to be much less effective because it kills the bacteria that are used to create the immune response. If you’re going to have surgery, be sure that the doctor or dentist knows you’re taking this, as well as anything else you’re taking.

If you’re pregnant, you should only take this medication if it’s badly needed. Pregnant women who take this medication during the last couple of months of the pregnancy can have a higher risk of bleeding, and so can the infant. If you see that your newborn is bleeding, contact the doctor immediately. If you’re breastfeeding, talk to your doctor about whether it’s ok while taking this medication. It’s unlikely to cause any harm to a baby, but the medication does pass into breast milk.

Don’t take this medication if you currently have jaundice. It’s also important not to take it if you’re taking medicines for HIV or AIDS. Before you drive while on this medication, make sure you know how it will affect you and whether it will make driving less safe.

Side Effects of Rifadin

There are a lot of side effects possible with this antibiotic. Some of them are mild and don’t require any treatment. Others may be severe and require either telling your doctor about them or seeking treatment as soon as possible. Many people get a headache, heartburn, an upset stomach, or nausea when they take this medication. If these effects don’t go away or worsen, tell your doctor about them.

There is a strong effect that might seem frightening, but it is actually not anything to worry about. This is the change of colors of your bodily fluids, including tears, sweat, urine, and saliva. They may change to red, yellow, brown, or orange. When you stop taking this medication, this effect will be gone. However, your teeth can be permanently stained by taking this medication. If you wear contacts, those can be stained as well.

These symptoms may signify that something is wrong and you’re having severe effects from the medication, such as developing a liver injury. This medication can cause fatal liver disease in rare cases. The symptoms of liver problems include vomiting that lingers, stomach pain, loss of appetite, dark urine, and more. If you have the symptoms of kidney problems, like easy bleeding, bruising, and confusion, get help right away.

This medication can cause a buildup of a bacteria known as C. difficile. The effects of this include mucus or blood in the stool, cramping or other stomach pain, and diarrhea that goes on and on. This can be a severe infection, and you need medical treatment if you have it. If you do get these symptoms, don’t use an opioid medication or an anti-diarrheal to treat it. These can cause the side effects to be even worse.

Suppose you are allergic to this medication. In that case, you may experience a fever that lasts, swelling of your lymph nodes, trouble breathing, severe dizziness, rash, swelling, or itching of the face or inside the mouth.

Several side effects can be serious and may require quick medical intervention. These include:

  • Severe bruising or bleeding
  • Serious stomach cramping
  • Loss of appetite
  • Severe diarrhea
  • Tuberculosis that gets worse
  • Swollen lymph nodes
  • Short of breath
  • Weight loss
  • Cough
  • Nausea or vomiting
  • Light-colored stools
  • Dark urine
  • Fever
  • Yellowing of the skin or eyes
  • Upper stomach pain
  • Feeling tired
  • Itching
  • Mood or other mental changes
  • Tiny red skin spots
  • Chest pain

Rifadin Drug Interactions

If you have a drug interaction with Rifadin and another drug, it may change the way one or both of them work, and it can put you at risk for several severe side effects.

If you take birth control pills (such as Seasonique), this medication may make them less effective. To have reliable birth control while you take this medication, it’s essential to find another way to prevent pregnancy.

This medication can also cause specific lab tests to have false results. Ensure the doctor and the lab you use know you’re taking this medication.

This drug reacts badly with several medications. It can cause other medications to leave the body too quickly so that they don’t work as well. These include:

  • Atovaquone
  • Anti-cancer medications like irinotecan
  • Some calcium channel blockers like nifedipine
  • Many HIV medications, such as etravirine and atazanavir
  • Some azole antifungal medications like itraconazole (found in Sporanox)
  • Certain medications for chronic hepatitis C
  • Cobicistat
  • Lurasidone (found in Latuda)

Rifadin Strengths and Dosages

This medication is available in tablet form in strengths of 150 mg and 300 mg. The dose a patient gets depends on the specific illness being treated. This medication is also available as a reconstituted powder for an injectable solution. This comes in 600 mg.

Tablets:150 mg, 300 mg
Powder for injectable solution:600 mg

FAQs of Rifadin 

Can you take this medication while you’re pregnant?

In the last few weeks of a pregnancy, this medication can cause harm to both the baby and the mother by causing each of them to bleed. This medication should only be taken during pregnancy when there’s a clear and specific need for it.

Is this an expensive medication?

It’s a mid-range drug that isn’t overly expensive but may be hard for some to afford. The 300 mg tablets can go for about $300 for 60 of them.

Should I worry if this medication makes my sweat and urine colored differently?

No, unless your urine is quite dark, there’s no need to worry about this. It’s just a temporary side effect that won’t hurt you.

Does this medication come in an oral suspension?

No, taking it orally requires taking it in tablet form.

Can you take Rifadin with birth control pills?

This medication can make these pills less effective. It’s essential to have an alternative form of birth control while you take Rifadin.

What forms does Rifadin come in?

Rifadin comes in a capsule and a powder reconstituted to become an injectable solution. Professionals in a healthcare setting typically use the injectable solution.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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