Advair is a prescription medication designed to provide adequate relief for individuals who have asthma and chronic obstructive pulmonary disease (COPD). This inhalation powder combines two active ingredients, fluticasone propionate, and salmeterol, to address inflammation and bronchoconstriction, offering comprehensive respiratory support.

Advair Diskus is used in patients aged four and older. The Advair HFA system is used in patients aged 12 and older. Both of these forms are inhalers.

When patients are prescribed Advair, it’s meant to prevent and control symptoms caused by asthma or a chronic or ongoing lung disease. When the symptoms of these conditions can be decreased, including wheezing and shortness of breath, it can improve the quality of life for patients.

This medication is generally used for asthma when another medication is used and it doesn’t control the condition. It’s used daily to be effective. It isn’t a fast-acting medication that is taken during an asthma attack. Instead, it’s used daily to help control the condition and prevent problems before they occur. If a patient has an asthma attack while on this medication, they need to use their fast-acting inhaler, often albuterol (such as Proair Respiclick).

How Does Advair Work?

The combination of fluticasone propionate, an inhaled corticosteroid, and long-acting beta-agonist salmeterol delivers a dual-action approach. Fluticasone reduces inflammation in the airways, addressing the root cause of symptoms, while salmeterol helps to relax and open the airways, allowing for improved breathing. The unique Diskus device ensures precise and convenient dosage administration with each use.

Precautions and Warnings of Advair

Before using Advair, certain precautions and warnings should be considered if any of the following apply to you:

  • Pregnancy and Breastfeeding: Use with caution during pregnancy and breastfeeding, with a thorough risk-benefit assessment.
  • Liver and Kidney Issues: Inform your healthcare provider if you have pre-existing liver or kidney conditions for a case-by-case evaluation.
  • Allergies: Individuals with known allergies to fluticasone, salmeterol, or related components should avoid Advair.

Side Effects with Advair

While Advair is generally well-tolerated, you may still experience side effects.

Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Throat irritation
  • Muscle pain
  • Hoarse or strained voice
  • Bone pain
  • Thrush, a mouth or throat fungal infection
  • Colds and other upper respiratory infections

Severe Side Effects

It’s possible to have an allergic reaction to this medication. This can be mild or severe. A mild reaction may include flushing, itchiness, and a rash. A more severe reaction can be mouth, tongue, or throat swelling. It may also cause difficulty breathing and swelling in the lips, feet, hands, or eyelids.

If you have these, you may need to get emergency medical care. These side effects include:

  • Weakness
  • Fatigue
  • Hypoglycemia
  • Cough or trouble breathing
  • Bone fractures from decreased bone density
  • Eye problems like cataracts and glaucoma
  • Pneumonia

Advair Drug Interactions

Several classes of drugs can cause problems when used with Advair. Many antiviral medications can cause adverse reactions in patients taking Advair. These include atazanavir, saquinavir, ritonavir, Viracept, and indinavir. These can raise the levels of salmeterol and fluticasone in your body, resulting in worse side effects. If you’re taking an antiviral for HIV, you may need to be changed to a different medication for the disease.

Several antifungal medications and antibiotics shouldn’t be taken with Advair. These medications can stop the salmeterol and fluticasone from breaking down in your body, leading to too much of it building up. These medications include clarithromycin (Biaxin), itraconazole (Sporanox), ketoconazole, and voriconazole. If it’s necessary to take these while you take Advair, your doctor must monitor you to ensure there isn’t a problem.

Some antidepressants can react with Advair and cause a greater risk of heart problems. These medications include phenelzine, isocarboxazid, imipramine, selegiline, and desipramine.

Some heart rate or blood pressure medications can raise the risk of developing severe breathing problems for patients who are also taking Advair. These medications include carvedilol, metoprolol, propranolol, and atenolol (Tenormin). It’s also important not to take certain diuretics with Advair. These include chlorthalidone, torsemide, furosemide, and hydrochlorothiazide.

Strengths and Dosages of Advair

Advair Diskus is available in different strengths, and the prescribed dosage depends on the severity of the condition. The recommended dose is typically administered twice daily. The Diskus device provides a user-friendly and reliable method for inhalation, ensuring consistent and accurate dosing.

100/50 mcgModerate to severe COPD: 1 inhalation 2x daily
250/50 mcgAsthma: 1 inhalation 2x daily for patients over 12 years old
500/50 mcgSevere asthma: 1 inhalation 2x daily for patients over 12 years old

Frequently Asked Questions With Advair

What are the different types of Advair?

There are two types- Advair Diskus and Advair HFA. Each works differently, and both can be used to treat asthma. Diskus can also treat COPD, but HFA can’t.

What is the cost of Advair in America?

The cost of Advair in America can vary based on dosage and location. On average, it may range from $300 to $600 for a one-month supply.

Can Advair be used as a rescue inhaler?

No, Advair is not intended for sudden breathing problems and should not be used as a rescue inhaler.

How long does it take to see improvements in symptoms?

The time for improvement varies, but noticeable effects may take a few weeks. Please have a look at your doctor for a personalized assessment.

Are there any dietary restrictions while using Advair?

No specific dietary restrictions are associated with Advair use.

Can Advair be used in children?

Advair is approved for use in children aged four and older, but the dosage is adjusted based on the age and severity of the condition.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember, but do not double up on doses. Consult your doctor for guidance.

 Are there alternatives for pregnant individuals?

Pregnant individuals should consult their doctor for a thorough risk-benefit assessment, considering potential alternatives based on individual circumstances.

Can you drink alcohol while taking Advair?

There isn’t a known adverse reaction between the two. However, drinking alcohol in large volumes can damage part of the airways, and this can make your asthma or COPD worse.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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