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Nizoral Dandruff Shampoo (Ketoconazole)
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Nizoral is a medication that is used to treat dandruff and relieve related symptoms such as itching, scaling, and flaking on the scalp. This type of medication is considered to be of the azole antifungal class and is usually found being used in the form of shampoo. It is also sometimes used to treat pityriasis – a fungal infection appearing on the skin that can lead to lightened or darkened areas on the neck, chest, or limbs.
Nizoral works by being applied to the scalp and wet hair. It should be used on hair wet with water and then lathered and massaged into the whole scalp. It should then be rinsed with warm water. That gives it enough time to treat the target area and weaken the fungus cells. The amount of applications and how long the shampoo should be left on before rinsing may vary from person to person.
Labeled Warnings of Nizoral
The FDA has issued several warnings and limited the use of Nizoral in 2016 – particularly the oral tablet version. The FDA warns Nizoral can lead to the possibility of fatal liver injury called “Hepatotoxicity,” adrenal insufficiency, and may lead to life-threatening heart problems if combined with certain medications. The topical Nizoral forms, like the shampoo, gels and creams, are not known to have these same severe side effects.
Nizoral Precautions
There are several Nizoral warnings and precautions. Severe hypersensitivity reactions, including anaphylaxis, have occurred in some cases while taking Nizoral shampoo. If any chemical irritation starts to appear while taking Nizoral, the medication should be stopped immediately. The long-term impact, including the development of carcinogenesis, mutation, or impairment of fertility, is unknown. Nizoral should also be avoided during pregnancy unless a doctor says otherwise. It is unknown if this Nizoral passes into breast milk and therefore should be avoided while breastfeeding.
Nizoral Side Effects
Nizoral has several possible side effects.
Common Side Effects
Most people should not experience serious side effects while taking the medication. If any of these symptoms seem to worsen or will not go away, talk to your doctor about how you should proceed.
Some common side effects of Nizoral include:
- Changing hair texture
- Oily hair or scalp
- Dry hair or scalp
- Scalp irritation
- Discoloration
- Pimple-like bumps
- Headache
- Upset stomach or nausea
Severe Side Effects
Severe side effects from Noxafil that require medical attention include:
- Hair loss
- Vision changes
- Mental or mood changes
Very Severe Side Effects
Very severe side effects that require immediate medical attention include:
- Rash
- Itching
- Swelling
- Severe dizziness
- Difficulty breathing
Drug Interactions with Nizoral
Some drugs are known to interact with Nizoral. These drugs should not be taken at the same time the patient is taking Nizoral, including:
- Alprazolam
- Midazolam
- Triazolam
- Cisapride
- Dofetilide
- Eplerenone
- Ergot Alkaloids
- HMG-CoA Enzyme Inhibitors
- Nisoldipine
- Pimozide
- Quinidine
- Alfentanil
- Sufentanil
- Fentanyl
- CYP3A4 metabolized calcium
- hannel blockers
- Bosentan
- Buspirone
- Busulfan
- Carbamazepine
- Cyclosporine
- Digoxin
- Docetaxel
- Indinavir
- Saquinavir
- Methylprednisolone
- Oral Anti-Coagulants
- Oral Hypoglycemic Agents
- Rifabutin
- Sildenafil
- Sirolimus
- Tacrolimus
- Telithromycin
- Tolterodine
- Trimetrexate
- Verapamil
- Vinca Alkaloids
Strengths and Dosages of Nizoral
Nizoral 1% dandruff shampoo should be lathered in wet hair, rinsed thoroughly, and repeated every 3 to 4 days for a duration of up to 8 weeks. Some prescriptions may call for multiple washes with the shampoo at a time and additional use for dandruff control.
If being used to treat other fungi on the skin, such as tinea versicolor, the 2% shampoo should be lathered onto the affected area of the skin while it is damp and rinsed after 5 minutes. This typically only needs to be done once and then followed up with daily cream for approximately 2 weeks.
For the oral dose of Nizoral, the typical adult dose is 200 mg per day, which may be increased as needed. For children aged 2 and older, the typical dose is based on weight. The amount is usually between 3.3 mg and 6.6 mg each day for each kilogram of body weight.
| Nizoral Form | Usage Instructions | Typical Dose |
| 1% Dandruff Shampoo | Lather into wet hair and rinse thoroughly. Repeat every 3-4 days for up to 8 weeks. This may require multiple washes per use for dandruff control. | N/A |
| 2% Shampoo (Skin Fungi) | Lather onto damp affected skin and rinse after 5 minutes. Only one application is needed in most cases. Follow with a daily cream for ~2 weeks. | N/A |
| Oral Dose (Adults) | Take once daily | 200 mg per day |
| Oral Dose (Children) | Take once daily | 3.3 mg – 6.6 mg per kg of body weight per day |
Nizoral Alternatives
There are several different possible Nizoral anti-dandruff shampoo alternatives that can be applied to the skin to stop the growth of fungi. Some alternatives to Nizoral include:
- Ketoconazole topical
- Nizoral A-D
- Nizoral Topical
- Xolegel
- Ketodan
- Extina
- Selenium sulfide topical
- Kuric
Nizoral FAQs
How do you use Nizoral shampoo?
Nizoral shampoo should be used by first wetting the hair and scalp and then applying a small amount to the hair. The shampoo should then be gently massaged into the scalp and left for about 3-5 minutes before rinsing with warm water. In most cases, the shampoo should be used once every 3 to 4 days for a duration of up to 8 weeks.
How often do you use Nizoral for hair loss?
Nizoral shampoo is not FDA-approved specifically for hair loss, although some do suggest it helps. For hair loss prevention, the shampoo should be used 2-3 times each week.
Why is Nizoral good for hair loss?
Nizoral shampoo may help with hair loss because it contains ketoconazole, which kills the fungus known for causing dandruff and hair loss, called “Malassezia.” This same fungus has been linked to male pattern baldness and hair loss acceleration. Nizoral also may improve the scalp’s microflora and reduce inflammation.
How long to leave Nizoral on the scalp?
Most professionals suggest leaving Nizoral on your scalp for at least 3-5 minutes before rinsing.
Who makes Nizoral?
Nizoral is made by Kramer Laboratories, Inc.
When can I use Nizoral after a hair transplant?
Nizoral shampoo can be used 4-6 weeks after a hair transplant if you have dandruff.
What should I avoid while taking Nizoral?
When using Nizoral anti-dandruff shampoo, avoid getting the product in your eyes, preventing air from getting to the treated areas, sunlight, and skin-irritating products. You should also avoid using other medications to treat the same areas unless a doctor says otherwise.
Our Guarantee For Buying Nizoral Dandruff Shampoo From A Canadian Pharmacy Partner
At MyRx Outlet, we are committed to delivering safe, high-quality medications that you can trust. We adhere to strict regulations in every country we operate in, ensuring that your order is handled by a licensed Canadian pharmacy or a trusted partner overseas. Each medication has been legally approved by Health Canada or other respected authorities. To purchase Nizoral Dandruff Shampoo at a discounted rate, call 1-888-551-2467.
IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.
