Lamisil is a brand name for the active ingredient terbinafine hydrochloride. It’s an antifungal antibiotic that treats fungal infections, generally of the fingernails or toenails. Lamisil is available under this brand name and its generic name. This medication works by keeping a fungus from growing.

Lamisil Forms

Lamisil comes in a prescription tablet, but over-the-counter types of this medication are used topically. It comes in a cream, spray, and gel that can be used for specific fungal infections. There is Lamisil AT gel, Lamisil AT spray, and Lamisil cream when using OTC Lamisil preparations. It was once available in granules, but those have been discontinued in the U.S.

Lamisil Precautions and Warnings

When using Lamisil, some patients have gotten severe liver damage that has led to needing a liver transplant as well as death. While taking this medication, let your doctor know if you have any symptoms of liver damage. These can include clay-colored stools, pain in the upper stomach, loss of appetite, nausea, dark urine, yellowing of the eyes or skin, vomiting, or tiredness. If you have these symptoms, contact your doctor right away. You may need to have testing to find out whether you have liver damage.

If you already have liver disease or you’re allergic to this medication, you shouldn’t take it. Make sure that you tell your doctor if you have or have had any liver problems, a weak immune system, kidney problems, or lupus. Likely you won’t be able to take this medication if you have any of these conditions.

If you have allergies to other substances, make sure that none of them are in this medication as an inactive ingredient.

While you’re taking this medication, limit the amount of alcohol you drink. If you drink every day, it can give you a higher chance of developing severe side effects.

Lamisil can make you have a higher degree of sun sensitivity. Don’t go out in the sun unless you need to; limit your time spent outside on sunny days. Don’t use any sunlamps or tanning booths. Wear protective clothing when you do go outside. Using sunscreen can also help protect your skin. If you get a sunburn or blisters or redness on your skin, tell your doctor about it immediately.

If you’re going to have surgery, tell the dentist or doctor that you’re taking this medication, as well as any other medicines that you take.

It’s generally recommended that women not use this medication while they’re pregnant. Treating a fungus on the fingernails or toenails can always wait until after pregnancy. This medication can pass into breast milk, and this may cause adverse effects on the baby. It’s recommended that you not breastfeed while you’re using it.

Lamisil Side Effects

Lamisil side effects can be broken down into common, severe as well as having an allergic reaction

Common Side Effects

Some side effects are more common with Lamisil than others. Several common side effects may be manageable. These include:

  • Headaches
  • Abnormal liver function tests
  • Rash
  • Stomach upset
  • Stomach pain
  • Nausea
  • Diarrhea
  • Gas

Serious Side Effects

If you have the symptoms of liver damage, it’s essential to talk to your doctor immediately. These effects can include clay-colored stools, dark urine, vomiting, nausea, yellowing of the eyes or skin, upper stomach pain, or unusual tiredness. It’s also important to tell your doctor right away if you experience any of these side effects:

  • Depressed mood
  • Lack of interest in your usual activities
  • Changes in smell or taste
  • Feeling restless or anxious
  • Insomnia
  • Rapid weight gain
  • Skin sores
  • Weight loss
  • Pale skin
  • Easily bruising
  • Little to no urinating
  • Red or purple pinpoint dots on the skin
  • Unusual bleeding from the rectum, vagina, mouth, or nose
  • Blood in stools or urine

Allergic and Drug Reactions

It’s possible to have a severe drug reaction to this medication. If this happens, the side effects include severe weakness, flu-like symptoms, skin rash, swollen glands, muscle aches, fever, unusual bruising, or yellowing of the eyes or skin. These symptoms can start after you’ve been using the medication for a few weeks. If you have any of these symptoms, talk to your doctor immediately. You may have to be changed to a different medication.

Patients rarely have a severe allergic reaction to Lamisil, but it’s possible. If you have this type of reaction to Lamisil, you may have swelling in your throat or face, difficulty breathing, and hives. If these or other serious side effects occur, immediately call for emergency medical care.

Lamisil Drug Interactions

Many medications can adversely interact with Lamisil. It’s essential not to take this medication with thioridazine. It can also interact with caffeine, beta-blockers, MAOIs like Nardil and carbs, cyclosporine, cimetidine, amiodarone, and other medicines for irregular heartbeats, Rifadin, and warfarin. It can also interact with tricyclic antidepressants such as imipramine, amitriptyline, desipramine, and more. It would be best if you also avoided SSRIs such as fluoxetine, citalopram, paroxetine, fluvoxamine, and sertraline.

There may be other medications that interact with Lamisil. Ensure your doctor knows everything you take, including herbs and supplements and OTC medications.

Lamisil Strengths and Dosages

There are many forms of this medication, some prescription and others OTC. The tablets are by prescription only. They come in a 250 mg strength. The various topical variations of this medication come in different strengths. Lamisil AT Cream comes in a 1% concentration of the active ingredient. Lamisil AT gel is also in a 1% concentration. The spray also comes in a 1% concentration.

Tablets: 250 mg
Lamisil AT Cream: 1%
Lamisil AT Gel: 1%
Lamisil AT Spray: 1%

When used for a fingernail fungal infection, the medication is often prescribed at 250 mg daily for six weeks. Toenails are generally prescribed at 250 mg for 12 weeks.

FAQs of Lamisil

Can you drink alcohol while taking this medication?

It’s ok to drink a small amount while taking this medication. However, drinking every day or drinking a lot can cause problems. This medication can cause liver problems in some patients, and if you drink alcohol, you may be at higher risk.

Is there a prescription Lamisil cream?

No, the tablet is the only form of this medication available by prescription. The cream is available over the counter.

What does Lamisil treat?

It’s generally used to treat fungal infections of the toenails or fingernails.

Is this medication effective against fungal infections?

It doesn’t work for some patients but for many others. It’s a medication that’s been on the market for years, and people get relief from their fungal nail infections when they take it.

Can you use Lamisil when you’re pregnant?

It’s best not to use it during pregnancy. It’s unclear whether it causes any risk, and it’s always possible to wait to use it until the baby’s birth. It also shouldn’t be used while breastfeeding.

Are there side effects possible when taking Lamisil?

Taking the tablet form of this medication can cause several side effects, which are generally mild. These include headaches, nausea, upset stomach, and gas.

Can you take this medication if you have liver disease?

No, it shouldn’t be taken by any patients with liver disease.

Can severe allergic reactions happen with this medication?

Yes, it’s rare, but some patients do have a severe reaction to Lamisil. This will generally come with hives, trouble breathing, and swelling or itching of the face or mouth.

Is it ok to consume caffeine while taking Lamisil?

It’s best not to have any caffeine while on this medication.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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