Diamicron is the brand name of the medication gliclazide, which is in the oral hypoglycemics class. Diamicron treats patients with type 2 diabetes. The medication helps patients keep their blood glucose levels under control. Patients are supposed to use this medication as part of a treatment plan that includes exercise and eating a healthy diet.

This medication causes the pancreas to release more insulin and assists the body in better using insulin. It’s often given when eating well, exercising, and reducing weight haven’t kept blood sugar under control alone. It’s classified specifically as a sulfonylurea, a type of medicine that helps the pancreas release more insulin.

There are two types of this medication, Diamicron and Diamicron MR. Diamicron MR stands for modified release. This medication version is a slow-release tablet while the other version is a standard-release tablet.

Diamicron Precautions and Warnings

Don’t take this medication if you’re at all allergic to it. While taking it, don’t use alcohol. It can lead to an intolerance reaction that can cause problems like nausea and increased heart rate. You may also develop anemia when taking this medication. Some patients have this reaction when they have the condition known as G6PD. If you have this condition, make sure your doctor knows.

Hypoglycemia is a common problem that can occur when you take Diamicron. If your blood sugar gets too low, it can cause many effects, such as drowsiness, dizziness, shakiness, nervousness, tingling, or sweating. People who have kidney or liver problems or are over 65 are more likely to have this problem.

Taking this medication can keep your body from responding effectively to stress or trauma such as an injury or surgery. If you aren’t able to heal well, your doctor might take you off the medication and put you on a different one while you heal.

If you have any kidney problems that reduce the function of your kidneys, you may not be able to take this medication. Make sure the doctor knows about your condition. With lowered kidney function, this medication can build up too much in the body and cause a wide range of effects.

The same can happen if you have any reduction in liver function. Talk to your doctor about your condition and whether you can take Diamicron. If you do, you must likely be closely monitored for problems. Even if you don’t have existing liver problems, this medication can cause them. Call your doctor immediately if you get yellow eyes or skin, pale stools, dark urine, fatigue, or abdominal pain.

If you have porphyria, make sure your doctor knows. This medication can make the condition worse. If you do take it, you may need to have special monitoring of your condition.

If your diabetes gets worse, this medication may not work as well for you anymore. If you find that this medication is no longer helping you have reasonable control over your blood sugar levels, be sure to tell your doctor right away.

There is no data about whether this medication is safe or effective for children. If you’re pregnant, you shouldn’t take it because it could possibly harm the baby. It’s unknown whether it is found in breast milk. Discuss taking the medication and breastfeeding with your doctor and consider possible risks.

Diamicron Side Effects

Many side effects are possible when you take Diamicron. However, many people don’t have any or only rarely have a problem. Some patients may have side effects that go away after a week or two because their bodies adjust to the medication.

Common Side Effects

Some of the common side effects include:

  • Nausea
  • Vomiting
  • Abdominal pain
  • Headache
  • Joint, muscle, or back pain
  • Heartburn
  • Constipation
  • More sensitivity to the sun
  • Dizziness
  • Diarrhea

Serious Side Effects

If these side effects bother you or get severe, let your doctor know about the problem. You may need to have your dosage changed or to try another medication. Some of the more serious side effects possible include:

  • Leg swelling
  • Hives or skin rash
  • Symptoms of liver problems – vomiting, loss of appetite, pale stools, dark urine, weight loss
  • Signs of low blood sugar – dizziness, shakiness, sweating, anxiety, rapid heartbeat, confusion, blurry vision, slurred speech
  • Weight gain that’s unexpected

Severe Side Effects

If you have any of these symptoms, let your doctor know right away. They could mean that you have a serious health problem. If you have any of the following serious symptoms, call for medical help and stop taking this medication:

  • Seizures
  • Chest pressure or pain
  • Shortness of breath
  • Unconsciousness
  • Symptoms of a serious skin reaction – peeling or blistering, a very large rash, a quickly spreading rash, a rash that comes with joint pain or body aches
  • Symptoms of a severe allergic reaction – nausea, vomiting, abdominal cramping, swelling in the throat or face, difficulty breathing

Interactions With Diamicron

There are a large number of medications, and types of medications, that can have a poor interaction with Diamicron. Certain herbs and other substances may also have a bad interaction. Make sure that you tell your doctor about everything you take, even if it’s something that’s over the counter. Some interactions include:

  • Acetylsalicylic acid
  • Beta-blockers such as propranolol
  • Alcohol
  • Atypical antipsychotics such as risperidone and clozapine
  • Azole antifungals such as miconazole and fluconazole (Diflucan)
  • Clarithromycin (Biaxin)
  • Oral corticosteroids such as prednisone and hydrocortisone
  • Barbiturates such as phenobarbital
  • Cyclosporine (Restasis)
  • Certain diabetes medications like metformin or glyburide
  • Estrogens
  • Fluvastatin
  • H2 receptor antagonists like famotidine and ranitidine
  • Protease inhibitors for HIV such as ritonavir (Norvir) and atazanavir
  • Milk thistle
  • Niacin
  • Progestins
  • NSAIDs like ibuprofen
  • Birth control pills
  • Progestins
  • John’s wort
  • Quinine
  • Sulfonamide antibiotics like sulfamethoxazole
  • Testosterone
  • Warfarin

Strengths and Dosages of Diamicron

The tablets are available in an 80 mg dosage. The tablets are scored so that they can be broken into four pieces if necessary. The Diamicron MR tablets come in 30 mg and 60 mg. Your specific dosage will be chosen based on your condition, other conditions you have, and possible other factors.

Diamicron tablets:80 mg
Diamicron MR tablets:30 mg, 60 mg

Diamicron Alternatives

There are a number of generics made of this medication as well as other brand names that are used for the same gliclazide that is the active ingredient in Diamicron. Some of the other brand names include: Dacadis, Zicron, Edicil, Nazdol, Laaglyda, Vamju, Glydex, Lamzarin, and Ziclaseg. There are also a number of other diabetes medications that could be alternatives. These include: Trajenta, Farxiga, Rybelsus, Jardiance, and Januvia.

FAQs of Diamicron

When to take Diamicron?

It’s generally taken in the morning along with breakfast. Taking it with food can help to prevent having too little blood glucose.

What does Diamicron MR 60 mg do?

Diamicron MR is a modified release tablet that releases more slowly and consistently than the regular Diamicron tablets.

When should Diamicron be Taken?

It generally should be taken once a day in the morning with breakfast.

Can you drink alcohol while taking this medication?

No, alcohol is contraindicated.

Can you take Diamicron while pregnant?

No, it’s generally not considered to be safe during pregnancy. There are other medications that could work for your diabetes and come with less risk than this one.

Why is Diamicron prescribed?

It’s a diabetes medication that is prescribed to help some diabetic patients by helping the pancreas to release more insulin. It also helps the body to use its insulin better.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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