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Ranitidine is a medicine that is prescribed to treat certain ulcers of the stomach and intestines and prevents them from coming back after they have healed.
This medication can be used to treat certain stomach and throat problems such as Zollinger-Ellison Syndrome, Gastroesophageal Reflux Disease (GERD), and Erosive Esophagitis.
The medicine belongs to a class of drugs known as histamine H2 blockers and has an active drug called Ranitidine. It inhibits histamine H2 receptors located on the surface of parietal cells in the stomach lining and the blockade leads to the reduction of acid produced by the stomach, thereby treating conditions where excessive gastric acid secretion causes certain symptoms such as heartburn, acid reflux, and peptic ulcers.
The medicine may be prescribed to treat symptoms more than those mentioned above.
As of April 2020, this medication has been withdrawn from the US market due to safety risks. An investigation found certain ranitidine products contaminated with a carcinogen named N-nitrosodimethylamine. However, in Canada, Ranitidine is available.

Precautions and Warnings with Ranitidine
There are chances of you developing pneumonia due to long-term use of this medicine.
The effects of Ranitidine on unborn babies are unknown. You should consult with your healthcare provider if you are planning to get pregnant while taking this medicine.
The medicine may pass into a baby through breast milk. Breastfeeding mothers should inform their doctor before nursing their baby on this medication.
This medicine should not be taken by patients who are allergic to: ranitidine or H2 blockers.
You should tell your healthcare provider if you have a history of these conditions before taking this medicine.
- Porphyria
- Phenylketonuria
- Liver disease
- Kidney disease
- Lung diseases
- Immune system problems
- Stomach problems

Ritandine Side Effects
This is not the complete list of side effects that may occur when taking this medicine. Common side effects are temporary and go away on their own during the course of your treatment. You should stop taking the medicine if serious side effects take place.
You can discuss your concerns about the side effects with your healthcare provider. They may change the dosage, remove the medication, or prescribe an alternative if these symptoms persist.
You may experience certain side effects when treating symptoms associated with ulcers and acid reflux problems with Ranitidine. You should inform your healthcare provider if you are experiencing these conditions when taking the medicine.
Mild Side Effect
- Diarrhea
- Constipation
- Abdominal/stomach pain
- Vomiting
- Nausea
Serious Side Effects
- Allergic reactions (trouble breathing, hives, and swelling on the face, throat, lips, or tongue)
- Irregular heart function
- Loss of appetite
- Severe stomach pain
- Jaundice
- Dark urine
- Respiratory problems
- Chest pain
- Easy bleeding or bruising
- Cough with mucus
- Chills

Drug Interactions with Ranitidine
This is not the complete list of medicines that could interact with this medicine. You should discuss your concerns about the potential interactions with your healthcare provider.
You should share the list of the medicines (prescription, over-the-counter, and hormonal) you are taking with your healthcare provider and inform them of your alcohol, nicotine, caffeine, and street drug intake for safe and effective treatment with this medication.
There are certain medicines that could reduce the efficacy of Ranitidine when taken together. The interaction may also put you at risk of serious side effects of this medicine.
The medicines that may interact with this medication are:
- Acetaminophen
- Advair Diskus
- Aspirin
- Benadryl
- CoQ10
- Cymbalta
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Furosemide
- Lipitor
- Lyrica
- Metoprolol
- MiraLAX
- Nexium
- Paracetamol
- ProAir
- Singulair
- Tylenol
- Vitamins B12
- Zyrtec

Strengths and Dosages of Ranitidine
Ranitidine is available in 150mg and 300mg strengths.
The ingredients (active and inactive) in this medicine are:
| Strengths | Active Ingredient | Inactive Ingredient |
| 150 mg (equivalent to 167.4 mg of Ranitidine Hydrochloride) | Ranitidine | Titanium dioxide, triethyl citrate, polydextrose, microcrystalline cellulose, colloidal silicon dioxide, croscarmellose sodium, hypromellose, magnesium stearate, and FD&C Yellow #6 |
| 300 mg (equivalent to 334.8 mg of Ranitidine Hydrochloride) | Ranitidine | Triethyl citrate, titanium dioxide, polydextrose, microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate, hypromellose croscarmellose sodium, and D&C Yellow #10 |
The medicine should be taken according as prescribed by your healthcare provider or according to the instructions on the description label.
Recommended Adult Dosage
| Symptoms | Dosage | Frequency | Additional Information |
| Active Duodenal Ulcer | 150 mg | Twice | An alternative dosage of 300 mg can be taken once daily after the evening meal or at bedtime.
A maintenance dose of 150 mg can also be prescribed at bedtime. |
| Hypersecretory Condition (Zollinger-Ellison Syndrome) | 150 mg | Twice | – |
| Benign Gastric Ulcer | 150 mg | Twice | A maintenance dose of 150 mg can also be prescribed at bedtime.
|
| GERD | 150 mg | Twice daily | |
| Erosive Esophagitis | 150 mg | Four times daily | A maintenance dose of 150 mg can be prescribed at bedtime. |
Recommended Pediatric Dose
| Symptoms | Dosage | Frequency | Additional Information |
| Duodenal and Gastric Ulcers | 2 to 4 mg/kg/day | Twice to a maximum of 300 mg/day | Maintenance doses of two to four mg/kg can be taken once daily to a maximum of 150 mg/day. |
| GERD and Erosive Esophagitis | 5 to 10 mg/kg/day | Usually given as two divided doses | – |
The recommended dosages for patients that have impaired renal function with creatinine clearance lower than 50 mL/min should be usually prescribed 150 mg every 24 hours. The dosing frequency can be increased to every 12 hours or even further.

Ranitidine Alternatives
There are several medicines that can treat symptoms of intestines and stomach ulcers along with Hypersecretory conditions as effectively as Ranitidine.
These alternatives have their pros and cons. You should not self-medicate on these medicines without your healthcare provider’s approval.
Your doctor may prescribe you the following alternatives if the medicine is unavailable or if your condition worsens due to interactions or risks of side effects of this medicine.

FAQs of Ranitidine
What is Ranitidine used for?
Ranitidine is a branded medicine that treats and prevents ulcers of the intestines and stomach and relieves symptoms of acid reflux, such as heartburn, cough, stomach pain, and difficulty swallowing. The medicine may also be prescribed to treat conditions that trigger the stomach to excessive acids, such as Zollinger-Ellison syndrome.
What are the similarities and differences between Ranitidine and Omeprazole?
| Feature | Ranitidine | Omeprazole |
| Mechanism of Action | Blocks histamine receptors on stomach cells | Inhibits proton pump |
| Type of Medication | H2 receptor antagonist | Proton pump inhibitor (PPI) |
| Onset of Action | Quick (within 30 minutes) | Slower (1-3 hours) |
| Duration of Action | Shorter (4-10 hours) | Longer (12-24 hours) |
| Uses | GERD, ulcers, Zollinger-Ellison syndrome | GERD, ulcers, esophagitis, Zollinger-Ellison |
| Availability | Over-the-counter and prescription | Prescription |
| Side Effects | Generally well-tolerated; headache, diarrhea | Generally well-tolerated; diarrhea, headache |
| Long-term Safety | Concerns about cancer risk (recently) | Generally considered safe, but long-term use may have risks |
Can Ranitidine cause cancer?
Yes, recent studies have raised concerns about ranitidine’s potential to form a probable carcinogen called N-nitrosodimethylamine (NDMA), especially when stored or used in conditions that promote its formation. The contamination led to the withdrawal of ranitidine products in several countries, including the USA.
How long does it take for Ranitidine to work?
Ranitidine typically starts reducing acid production within 30 minutes of oral administration.
How long does Ranitidine stay in your system?
Ranitidine has a short half-life of 2-3 hours. This means it is usually cleared from the body within 8-12 hours after the last dose.
What should you avoid while taking Ranitidine?
While taking ranitidine, it’s generally advised to avoid alcohol, smoking, and certain medications that can worsen stomach irritation. Discuss specific concerns with your healthcare provider.
Why was Ranitidine discontinued in the USA?
Ranitidine was discontinued in the USA due to concerns about NDMA contamination. NDMA levels in ranitidine products were found to increase under certain conditions (like high-temperature storage), posing potential health risks over time.
Why is Ranitidine available in Canada?
Despite the safety risks associated with Ranitidine, this medicine is available for sale in Canada. However, pharmaceutical companies have to follow standards to ensure the safety of those taking the medicine. Health Canada has enforced strict safety measures for the sale of ranitidine and companies have to test every batch for NDMA levels before release and throughout its shelf life. The authorities have recommended individuals on the medication not stop taking it without their healthcare provider’s approval, as the risks of untreated conditions may be higher than the potential risks of NDMA exposure.
Our Guarantee For Buying Ranitidine From A Canadian Pharmacy Partner
At MyRx Outlet, we are committed to delivering safe, high-quality medications that you can trust. We adhere to strict regulations in every country we operate in, ensuring that your order is handled by a licensed Canadian pharmacy or a trusted partner overseas. Each medication has been legally approved by Health Canada or other respected authorities. To purchase Ranitidine at a discounted rate, call 1-888-551-2467.
IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.