Vyzulta uses the active ingredient latanoprostene bunod, which works to treat high pressure on the eye. It is typically used for open-angle glaucoma but may be used for other eye conditions that cause eye pressure, such as ocular hypertension.

The Vyzulta eye drop ophthalmic treatment is used once per day in the affected eye. When used, it works to help drain fluid from the eye that causes pressure and inherently lowers eye pressure in the process.

Precautions and Warnings with Vyzulta

Before you start taking Vyzulta, talk to your doctor about whether or not it may be a good option. Your doctor needs to know your medical history and any allergies that you may have to medication. Share with your doctor all medications you are taking. Disclose prescriptions, over-the-counter drugs, vitamins, supplements, and herbs that you use.

Be familiar with these precautions and warnings before use.

AllergiesIf you are allergic to Vyzulta, the active ingredient latanoprostene bunod, or any inactive ingredients, be sure to tell your doctor
Eye ConditionsIf you have any eye conditions aside from what is being treated, disclose this to your doctor. This includes macular edema, iritis, uveitis, lens extraction, etc.
Risk of InfectionUsing Vyzulta eyedrops comes with a risk of eye infection. This risk is primarily associated with contamination of the eye dropper. Do not allow the eye dropper to touch your eye directly or to touch your hands or any other surface.
Swelling or Inflammation RiskIf you are prone to eye inflammation or swelling or currently have a condition causing inflammation, Vyzulta may make this worse. Speak to your doctor right away if you notice vision changes.
Changes to EyelashesExperiencing changes to your eyelashes is normal with Vyzulta. It may cause your eyelashes to grow longer and thicker. This is generally temporary.
Darkening of Eye or EyelidVyzulta may cause darkening of the eye or eyelid during use because of the prostaglandin. This increases the brown color of the eye and is most likely to occur with long-term use. These changes may be permanent even when you stop taking Vyzulta.
Pregnant or BreastfeedingIf you are pregnant or breastfeeding, consult with your doctor about the risks of taking Vyzulta. It is recommended that you only use this medication if needed during those times.

Vyzulta Side Effects

Regardless of whether your side effect is listed here, if it makes you worry, the best thing to do is reach out to your doctor.

Common Side Effects

These side effects should be temporary. However, if they concern you or if they do not go away, please reach out to your doctor. They can advise you further.

The most common side effects experienced with Vyzulta are:

  • Red eyes
  • Limited eye pain
  • Irritation to the eye
  • Darker eye color
  • Eyelash changes
  • Eye itchiness
  • Temporary blurred vision
  • Gritty feeling in the eye
  • Cornea inflammation

Serious Side Effects

If you experience any serious side effects or suspect an allergic reaction, you should seek medical care immediately. Some serious side effects may include these:

  • Intense eye pain
  • Eye swelling
  • Redness or swelling of the eyelid
  • Changes to vision
  • Dizziness
  • Difficulty breathing
  • Allergic reaction

Drug Interactions with Vyzulta

When taking Vyzulta, you may notice a difference in how other medications work. It can affect how medications, supplements, and OTC drugs work. In addition, some of these items may reduce the effectiveness of Vyzulta.

Speak to your doctor about anything and everything you are using so they can be aware and advise you if anything needs to change. You should not start, stop, or change your medications unless the doctor advises you to do so. They may advise you to make adjustments but wait for them before making changes.

It is unlikely that anything you are taking will affect how Vyzulta works, particularly with the way latanoprost affects your eye. You should still speak to your doctor to be safe and sure.

Cost of Vyzulta in America

On average, a 2.5ml of Vyzulta may cost anywhere from $150-$300 without insurance. The larger bottle of 5ml may cost $500-$600. This cost may vary depending on the pharmacy that you use as well as your location. You may be able to find programs that will help you get a discount to save some out-of-pocket expenses. At this time, there is not yet a generic option for Vyzulta, but in the future, that may become available.

Why Is Vyzulta Expensive?

Vyzulta is a name-brand prescription that has a very specific purpose. The ophthalmic treatment market is not a huge market, which means they sell much less than traditional, common medications. Because of that, prices must be higher in order to cover the costs of development, testing, production, marketing, and more.

You will find that many branded ophthalmic treatments fall into this category and can be quite expensive without insurance coverage.

Strengths and Dosages of Vyzulta

Vyzulta comes in two different sizes, but the strength remains the same across the board. It is important that you follow your doctor’s instructions for proper use of the medication. Typically, the dosage is to use one drop in the affected eye at night.

The two sizes of eye dropper bottles available are these:

  • 5ml at .024%
  • 5ml at .024%

Vyzulta Alternatives

Your doctor can determine whether an alternative will work for your needs.

There are some alternative choices to using Vyzulta. Consult with your doctor to determine the best first and whether an alternative may be an option for you. These are the most common alternatives:

FAQs of Vyzulta

What is Vyzulta?

Vyzulta is a prescription medication used to treat intraocular eye pressure. It is most commonly used for open-angle glaucoma, but may be used for other conditions that cause pressure too.

How Much Does Vyzulta Lower Eye Pressure?

Vyzulta helps to lower eye pressure by reducing the fluid buildup that causes pressure on the eye. The measurement of reduction is 7.5-9.1 mmHg.

When will Vyzulta Get a Generic Option?

It is unknown exactly when there will be a generic Vyzulta option. As of right now, the expectations for a generic option are speculating sometime in late 2025 or perhaps 2026.

How Long Does Vyzulta Last?

When stored properly, a bottle of Vyzulta will typically last for 8 weeks. Proper storage recommends storing the bottle in the refrigerator until it is opened. After it is opened, it may be stored at room temperature.

What is Vyzulta Used For?

Vyzulta is used specifically to treat intraocular pressure. In most cases, the pressure is caused by open-angle glaucoma. However, there are other conditions that cause intraocular pressure and these may also be treated with Vyzulta.

What Happens if Vyzulta is Not Refrigerated?

The bottle only needs to be refrigerated until you open it. You may store it in the refrigerator after opening, but it is not required. Vyzulta will last for up to 8 weeks stored at room temperature.

How Does Vyzulta Work?

Vyzulta works by reducing the pressure on the eye. That pressure is generally caused by excess fluid on the eye and Vyzulta helps to reduce that fluid.

Who Makes Vyzulta?

Vyzulta is made by Bausch Health. It is a fairly new ophthalmic treatment, which is why there is no generic option available yet.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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