Pazeo is an antihistamine eye drop medication that treats redness and irritation caused by allergies. This condition is also known as allergic conjunctivitis. Pazeo is the brand name for this drug, which is available as 0.7% liquid eyedrops. This medicine is also found in Patanol and olopatadine hydrochloride. Pazeo is only designed to treat allergic irritation. It isn’t recommended for other causes of eye irritation, including that caused by wearing contact lenses. However, doctors may prescribe it off-label for other purposes.

How Does Pazeo Work?

Pazeo is an antihistamine, which means it reduces the amount of histamine your body typically makes. Histamine is a natural chemical your immune system uses to signal cells throughout the body. Histamine is stored in white blood cells called mast cells which are normally found in connective tissue.

Histamine is typically released in response to outside substances, which are called allergens. Only a few outside substances are harmful to people. However, the immune system can make too much histamine in response to otherwise harmless substances. This triggers an allergic reaction, which can range anywhere from mild irritation to life-threatening symptoms.

Pazeo works by stabilizing mast cells so they don’t release as much histamine when triggered. It also functions as a histamine H1 antagonist by binding to receptors that normally communicate with histamine molecules. Pazeo blocks these receptors so histamine molecules can’t make contact. This prevents histamine from triggering allergic reactions even when it is released.

Pazeo Precautions and Warnings

You shouldn’t use Pazeo if you’re allergic to olopatadine hydrochloride or any of its other ingredients. Tell your doctor about all the medicines you take, including over-the-counter medications, vitamins, supplements, illicit drugs, and more. Make sure to mention any other eye drops you use, whether they are medicated or simply for hydration.

Pazeo can cause temporary blurry vision directly after it’s applied. Don’t drive or use heavy machinery after taking Pazeo until you know how it will affect you.

Pazeo is safe for contact-wearers to use in most situations. Take your contacts out before using Pazeo and leave them out for at least 15 minutes before reinserting.

Side Effects of Pazeo

Tell your doctor if these side effects don’t go away or if they get worse.

It’s rare, but some people are allergic to olopatadine hydrochloride or Pazeo’s other ingredients. Call your doctor immediately if you have trouble breathing, facial swelling or itching, trouble swallowing, or a rash.

Most side effects of Pazeo are temporary, mild, and limited to the application site. Pazeo side effects include:

  • Blurry vision
  • Feeling like something is stuck in your eye
  • Dry, itchy, or burning sensation in the eye
  • Eyelid swelling
  • Eye or eyelid redness
  • Headache

Drug Interactions With Pazeo

Eyedrops are unlikely to interfere with medicine you use in other parts of the body, including oral medicine that you swallow. However, interactions are still possible. Tell your doctor about all your medications to make sure they’re safe to combine with Pazeo.

Pazeo is most likely to interact with other eye treatments. If you use other eye drops, ask your doctor or pharmacist whether you should use them alongside Pazeo.

An inactive ingredient in Pazeo can stain contact lenses when it’s first applied. Wait at least 15 minutes after taking Pazeo before putting in your contacts to avoid this risk.

Strengths and Dosages of Pazeo

Pazeo is available in 4ml bottles of 0.7% olopatadine hydrochloride. There are also other strengths available over the counter.

Strength Also Known As Length of Effect
0.7% olopatadine hydrochloride Pazeo; Pataday Once Daily Relief Extra Strength 24 hours
0.2% olopatadine hydrochloride Pataday; Pataday Once Daily Relief up to 16 hours
0.1% olopatadine hydrochloride Patanol; Pataday Twice Daily Relief up to 8 hours

Alternatives to Pazeo

There’s not currently a generic version of Pazeo, but there are other antihistamine medications that treat allergic conjunctivitis. Alternatives to Pazeo include:

  • Allegra
  • Atarax
  • Benadryl
  • Cetirizine
  • Clarinex
  • Claritin
  • Claritin-D
  • Histex PD
  • Optivar
  • Palgic
  • Pataday
  • Patinas
  • Periactin
  • Phenergan
  • Promethegan
  • Vistaril
  • Xygal
  • Zyrtec

Pazeo FAQs

Why did my doctor prescribe Pazeo?

Pazeo is an antihistamine that treats allergic conjunctivitis, which is another term for itchy, red eyes caused by allergies. If you have eye irritation caused by allergies, then Pazeo should treat your symptoms. Pazeo doesn’t treat other kinds of eye irritation such as dryness caused by contact lenses.

How do I use eye drops?

Applying eye drops can feel complicated or unpleasant at first. However, it’s a skill you can learn with practice.

  1. Wash your hands, and take out your contacts if applicable.
  2. Tilt your head backward.
  3. Pull your bottom eyelid gently down, opening a small “pocket” under the eye.
  4. Hold the eye dropper above your eye and gently squeeze a drop into the “”
  5. Close your eyes for a minute.
  6. Repeat with the other eye.

Can I wear contacts while using Pazeo?

You can wear contact lenses while using Pazeo, but don’t wear them while applying Pazeo. You need to apply your eye drops without contact in your eyes. You also need to wait at least 15 minutes before putting your contacts back in after taking your eye drops.

Can I take Pazeo with other allergy medicine?

Ask your doctor if Pazeo is safe to take with other allergy medications. Oral antihistamines affect the entire body whereas Pazeo targets specifically the eyes. Taking too many antihistamines can have unwanted side effects including drowsiness, so ask your doctor what’s best for your situation.

What allergens does Pazeo fight?

Pazeo reduces your allergic response to a range of indoor and outdoor allergens, including ragweed, grass, pollen, animal hair, and dander.

Does Pazeo help with other eye problems?

No, Pazeo only helps with eye irritation caused by allergies. Dryness, redness, itchiness, and other allergic symptoms are caused by histamine overproduction. Pazeo reduces histamine levels and also reduces how your eyes respond to histamine. Other types of eye problems have different causes. Contacts, dusty environments, dry air, wind, and other eye irritants cause physical irritation which doesn’t trigger your allergic responses. Therefore Pazeo won’t help you feel better in those situations.

What is the cost of Pazeo in America?

Pazeo is only available as a name-brand drug from Novartis. There is not currently a generic alternative for Pazeo. One 4ml bottle of 0.7% Pazeo costs around $100 before any coupons or discounts.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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