Avamys is a prescription nasal spray that helps relieve respiratory symptoms from colds and allergies. Whether you are congested, sneezing a lot, have a stuffy or runny nose, or have a diagnosis of allergic rhinitis (the medical term), it works well to relieve any feelings of discomfort. The spray is made with fluticasone furoate, a potent corticosteroid that reduces inflammation inside your nose so you can target problem areas and relieve any pain.

This medication typically starts to work within 8 to 24 hours after the first dose but is recommended to take for several days so it can work properly.

How Does Avamys Work?

Avamys has an active ingredient, fluticasone furoate, which has an anti-inflammatory effect. When you spray Avamys into your nose, the medicine reduces swelling and irritation in the nasal passages. This helps to ease symptoms like a stuffy or runny nose, sneezing, and congestion by calming down the body’s reaction to things that might be irritating, such as allergens. Essentially, Avamys helps to make your nose feel better by soothing the inflammation and making breathing easier.  Avamys not only relieves the symptoms of allergic reactions but also addresses the underlying cause, making it a compelling choice for those who seek a solid solution for any nasal allergy symptoms.

Avamys Precautions & Warnings

It’s highly recommended that you check with your doctor before taking Avamys and read the medication labels. However, a few common conditions to be wary about using Avamys are listed below, along with some warnings.


Please note this is not a complete list of precautions. Your prescriber would only prescribe you this medication if they feel you are a suitable candidate.

  • Allergic Reactions: Avoid using Avamys if you have a known allergy, hypersensitivity to fluticasone furoate, or a history of allergies to nasal sprays. If you decide to use Avamys, monitor your body’s reactions, stop using immediately, and call your doctor if you experience itching, rash, swelling, severe dizziness, or difficulty breathing.
  • Nasal Infections and Wounds: If you’ve recently had nasal surgery or are prone to nasal sores, you’ll need to tell your doctor before use, as Avamys should be used with caution in these situations
  • Glaucoma and Cataracts: If you or your family have a history of glaucoma or cataracts, you’ll need to use it cautiously. Corticosteroids, including those in Avamys, may increase the risk of developing or worsening these conditions.
  • Pregnancy and Breastfeeding: As with most medications, consult your doctor before use if you are pregnant or breastfeeding. The potential benefits and risks should be discussed on a case-by-case basis.


This is not a full list of warnings with Avamys. If you are a current customer and would like to speak to one of our licensed pharmacists, please contact us.

  • Nasal Effects: If you use corticosteroid nasal sprays (including Avamys) for a prolonged period, you might experience more nosebleeds or persistent feelings of discomfort.
  • Immunosuppression: Corticosteroids may suppress the immune system, so if you are exposed to contagious diseases, you might develop an infection.
  • Ocular Effects: Use Avamys with caution if your vision has changed recently or you have a history of increased intraocular pressure.
  • Adrenal Suppression: Prolonged use of corticosteroids may lead to adrenal suppression.
  • Pediatric Use: The safety and effectiveness of Avamys in children under two years of age is not universally known or recommended for use.

Avamys Side Effects

Avamys is generally safe. Common side effects are usually mild and may improve over time. There are also several rare side effects to note.

Common Side Effects

  • Nasal Irritation
  • Nose Bleeds
  • Mild Headaches

 Less Common Side Effects

  • Sore Throats
  • Coughing

 Rare but Serious Side Effects

  • Hypersensitivity Reactions, such as a rash, itching, swelling, severe dizziness, or difficulty breathing
  • Nasal Septum Perforation: Rarely, but it has been reported that holes have begun to form in the nasal passage from overuse
  • Adrenal Suppression and Systemic Effects

Avamys Drug Interactions

Avamys may interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. Let your doctor know about all prescriptions you are taking and over-the-counter drugs, too, including vitamins and herbal supplements, because you never know what may cause an adverse reaction.

Since Avamys is a nasal corticosteroid, there is a possibility of interactions when used with other medications, including the following:

Ritonavir (Norvir): May increase fluticasone furoate levels in the blood, potentially increasing the risk of side effects.

Ketoconazole: It may also increase fluticasone furoate levels, which you need to be cautious about

Other Corticosteroids: It’s not recommended to use multiple medications that contain corticosteroids at the same time because you may increase your risk of systemic corticosteroid side effects. Examples of corticosteroids include Prednisone or Oracort Paste.

Avamys Dosage & Strengths

The recommended dosage and strength of Avamys (fluticasone furoate nasal spray) depends on your age, the severity of your symptoms, and your doctor’s assessment based on your unique medical history, other medications you are taking, and other symptoms.

The standard doses range from one to two sprays per nostril, one time a day.

You can buy Avamys in either seasonal or perennial form, and one spray contains approximately 27.5 mcg. Start with one spray per nostril once a day. Based on how your body responds or how severe your symptoms may be, you can increase the dosage to two sprays per nostril, but it is still recommended not to exceed once daily (which increases the dosage to 55 mcg per spray).

The drug comes in one strength, which is 27.5 micrograms per spray.

Cost of Avamys & Alternatives

Veramyst is the brand name for Avamys’ most significant competitor. Both brands contain the active ingredient fluticasone furoate.

There are several alternatives to Avamys on the market, too, with varying chemical compounds that generally have the same effect. Below is an estimated cost chart for many standard options, with OTC indicating products available Over The Counter. *The actual cost will vary depending on your state, pharmacy, and insurance coverage.

MedicationApproximate Cost

(30-day supply)

Active Ingredient
Avamys$100 – $150Fluticasone Furoate
Veramyst$120 – $150Fluticasone Furoate
Flonase (OTC)$15 – $25Fluticasone Propionate
Nasonex$150 – $200Mometasone Furoate
Rhinocort (OTC)$15 – $25Budesonide
Beconase AQ$80 – $100Beclomethasone Dipropionate

FAQ About Avamys

Is Avamys available over the counter?

No, Avamys is a prescription medication; you’ll need one from your doctor.

How often should I use Avamys?

The recommended dosage is one spray per nostril once daily or as your doctor directs. Don’t steer from the recommended dosage for optimal results.

Can children use Avamys?

Avamys is typically prescribed for individuals aged 12 and older. Please speak with your child’s pediatrician for appropriate alternatives if your children are under 12,  as their needs may differ.

Are there any long-term side effects of using Avamys?

Long-term use of Avamys may be associated with specific side effects, such as an increased risk of nosebleeds. Follow your doctor’s recommendations, and keep them updated if you have any concerns or issues.

Can I use Avamys if I’m pregnant?

Consult your doctor before use if you are pregnant, planning to become pregnant, or nursing. The potential benefits and risks should be carefully weighed in consultation with a qualified professional, depending on your situation.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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