Xyzal is a medication that treats year-round allergy symptoms as well as chronic hives. It’s in a class of medications known as antihistamines. When something causes an allergic reaction in a patient, their body will naturally release a chemical called histamine. This is what causes the allergic reaction that so many people have to year-round allergens like dust and pollen.

When histamines get released into the body, it causes a host of uncomfortable symptoms. These can include a runny nose, itchy eyes, watery eyes, sneezing, and an itchy nose. It can also cause itchy swollen skin known as hives. The medication can be used by those who are six months old and older.

When someone takes Xyzal, it blocks the histamines that can cause the reaction. It is used to treat mild to moderate allergies and not a severe allergic reaction like anaphylaxis. It also doesn’t prevent hives from appearing but can help treat them after they’ve appeared. If you have an EpiPen prescribed to you for severe allergic reactions, it can’t be replaced by Xyzal. So, carry the EpiPen with you and take Xyzal for milder allergy symptoms.

Xyzal Precautions and Warnings

The active ingredient in Xyzal is levocetirizine. If you have an allergy to this ingredient don’t take Xyzal. If you’re allergic to either hydroxyzine or cetirizine, tell your doctor and find out whether you can take this medication. You may also have an allergy to one of the many inactive ingredients. You can talk to your doctor or pharmacist about your allergies to make sure you should be taking Xyzal.

When you talk to your doctor or pharmacist about this medication, tell them if you have a history of kidney disease or have ever had a hard time urinating. This can happen because of an enlarged prostate. Also make sure they know if you’ve ever had gallbladder problems, kidney disease, or liver disease. If you have major health problems, discuss this medication with your doctor before using it.

It’s possible that this medication could make you drowsy, so be sure to see how it affects you before driving while on it. When you do take this medication, taking cannabis or drinking alcohol should be avoided because they will make the drowsiness worse. When you use the liquid form of this medication, it may contain sugar or a sweetener like aspartame. If you have diabetes or have phenylketonuria, you may not be able to take this medication.

Never give a child more than the appropriate dosage for their age. A child’s body will absorb double the amount of levocetirizine than an adult’s will. Never give it to a child just to make them sleepy. If you’re pregnant, make sure that you balance the benefits of taking it with any risks that may exist and only use it if you really need it. It’s known that this medication does get into breastmilk. You may want to talk to your child’s pediatrician about whether to take this while breastfeeding.

Xyzal Side Effects

Besides drowsiness, there are a number of other side effects that Xyzal can cause.

There are also serious side effects that can occur in some people, though they aren’t common. These include having trouble urinating, allergies that get worse, pain when you urinate, a dizzy and light-headed feeling, weakness, and being unable to urinate at all. If you have any of these symptoms, you should stop taking the medication.

It’s very rare, but it is possible to be allergic to this medication. If you have an allergic reaction to it, you may have a hard time breathing and/or get hives. Your lips, throat, face, or tongue could swell up as well, and this can be dangerous. If this happens, you should likely use an EpiPen if you have one and then get emergency medical attention.

Some of the most common side effects include:

  • Sinus pain
  • Cough
  • Nosebleed
  • Dry mouth
  • Ear infection
  • Fever
  • Weight gain
  • Constipation
  • Diarrhea
  • Vomiting

Xyzal Drug Interactions

Because Xyzal can make patients drowsy, it’s important not to take other things along with this medication that can also make you drowsy. This includes cannabis and alcohol as well as any type of opioid medication for pain or cough. These may include medications that contain hydrocodone or codeine. You should also avoid taking other antihistamines along with Xyzal.

If you take medications for seizures or anxiety, muscle relaxers, or sleeping pills, it’s important to ask your doctor before you take Xyzal. Some of the anxiety drugs that can interact with Xyzal include zolpidem, lorazepam, and alprazolam. Some of the muscle relaxers that can interact include cyclobenzaprine and carisoprodol. The doctor should also know if you take theophylline or ritonavir. The doctor should know all of your medications as well as any herbs or other supplements you take.

Before you take another medication with Xyzal, look to see whether it causes drowsiness. Many cold and cough medications can do this as well as other allergy meds. The active ingredient in Xyzal, levocetirizine, is a highly similar medication to cetirizine and hydroxyzine. These shouldn’t be taken along with Xyzal. You also shouldn’t use it with other antihistamines that are put onto the skin such as various sprays, ointments, and creams. Using both can mean side effects that are increased.

Xyzal Strengths and Dosages

There are different dosages for different uses of this medication. If you’re an adult who is taking Xyzal for hives, taking 5 mg can be done each evening. For some patients, 2.5 mg may be enough to help them with their chronic hives. If an adult is taking this medication for allergic rhinitis, the dose can be either 5 mg or 2.5 mg once a day.

The pediatric dose depends on the age of the child. When a pediatric patient who is aged six months to five years old takes it for allergic rhinitis, the dosage is 1.25 mg once every evening. Be sure not to administer any more than this. For children who are ages six to 12, the dosage is 2.5 mg once each evening to treat allergic rhinitis. Children over 12 can take the adult dose of 5 mg. When a child is being treated for chronic hives, the dosages are the same at each age. Be sure to ask your child’s pediatrician before giving them Xyzal, and make sure they know all the medications your child is on.

Xyzal is taken orally in either a tablet or a liquid form. If you or your child take the liquid version, make sure that you measure the liquid carefully with the designated measuring spoon or dropper. Never take more than the necessary dosage for your age and medical history. You can talk to your doctor or pharmacist about how much you should take if you have other health problems.

Allergic Rhinitis Hives
Adult Dosage 5 mg 5 mg
Children 6 months to 5 years 1.25 mg 1.25 mg
Children 6 to 12 2.5 mg 2.5 mg
Children 12 and up 5 mg 5 mg

Cost of Xyzal in America

There are two ways that you can get Xyzal- either over the counter or by prescription. Some doctors will prescribe this medication for patients who need it while others will recommend that you buy it over the counter. Your price depends on many factors including whether you have a prescription or are buying it OTC. If you have a prescription, you will likely owe a co-pay, though it could be more if you haven’t met your deductible yet. The price of it without insurance is about $25.

If you’re buying your Xyzal over the counter, you can expect to pay about $18 for a package of it. There are many companies that make generic forms of this medication. A package of the generic formula can be around $15.


Is Xyzal good for treating hives?

Yes, it can be taken for either allergic rhinitis or for hives (urticaria).

Does it have to be taken with food?

No, it shouldn’t upset the stomach if not taken with food. It can be taken either with or without it.

Can children take Xyzal?

Yes, there are pediatric dosages for children of various ages. Never give a child too much of this medication or give it to them to make them sleepy.

Can I take it and drink alcohol?

No, it shouldn’t be taken with alcohol. Alcohol would make the drowsiness that Xyzal can cause worse. The same is true for cannabis and medications that can cause drowsiness.

Can you be allergic to this medication?

Yes, even though it’s an allergy medication, it’s possible to be allergic to it. If you notice any signs of an allergic reaction, stop taking it and get medical attention, especially if the reaction is a serious one.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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