Vistaril has multiple uses. It reduces central nervous system activity and acts as an antihistamine. It’s often used to treat patients who are having tension and anxiety, and it does this by calming the nervous system. The antihistamine action works to help when someone is having allergy problems. When a patient has an allergy, it creates histamines in the body. This medication can reduce the effects of histamines in the body so that there are fewer symptoms like hives or itching on the skin.

As a sedative, it’s sometimes given to patients along with other medications during general anesthesia as well as afterward. It may also be taken by patients regularly for anxiety or on an as-needed basis when they have episodes of anxiety. It may also be prescribed for other issues like nausea vomiting and rashes.

Vistaril Precautions and Warnings

It’s essential not to take this medication during pregnancy. This is especially true in the first and second trimesters. If you find out that you’re pregnant, stop taking this medication right away and tell your doctor. It is known to cause congenital disabilities when taken during pregnancy. It isn’t known whether Vistaril passes into breastmilk, and it isn’t recommended that patients breastfeed while taking this medication.

Vistaril can cause heart problems in some patients, and that’s more likely when they are taking certain medications while taking this one. Ensure your doctor knows everything you’re taking before starting this medication. Vistaril can also cause impairment of reactions and thinking. If you need to drive while on this medication, wait until you know how it affects you.

If you have any severe side effects from this medication, stop using it and tell your doctor right away. These can include seizures, confusion, or tremors. It can also involve having restless muscle movements of the neck, jaw, tongue, or eyes. If you drink alcohol while taking this medication, it can make specific side effects worse.

This medication should not be given to children unless the doctor orders it. If you are allergic to Xyzal or Zyrtec, don’t take this medication. If you have a heart condition called long QT syndrome, this medication shouldn’t be taken. If you have a family history of this syndrome, ensure the doctor knows. You should be sure to tell your doctor if you have:

  • Urination problems or bladder obstruction
  • A digestive tract blockage in the intestines or stomach
  • Glaucoma
  • Slow heartbeats or any heart disease
  • An imbalance of electrolytes, including low or high blood potassium levels
  • If you’ve had a heart attack recently

Vistaril Side Effects

Many side effects could result from taking Vistaril. Some of them are more common than others. Some of them can be highly severe. It’s essential to keep your doctor informed about any side effects that bother you or may be severe.

Some common side effects that patients may get from this medication include headache, skin rash, blurry vision, drowsiness, upset stomach, or a dry mouth. Generally, these side effects tend to be mild. There are also serious side effects such as fainting, severe dizziness, seizures, a headache that presents with chest pain, or pounding or fast heartbeats. If you have any of these, you should seek medical help immediately.

If you have eye problems like tunnel vision, vision loss that happens suddenly, seeing halos appear around lights, swollen eyes, or eye pain, seek emergency medical care. If you have any shortness of breath, fluttering in your chest, pounding heartbeats, or you get lightheaded or pass out, these are also severe symptoms that must be treated immediately. You may also experience severe side effects like confusion, stiff muscles, tremors, a high fever, slurred speech, severe headache, or weakness in the arms or legs. If these happen, contact 911 or otherwise get emergency care.

If you are allergic to this medication, you may have difficulty breathing, get hives, or have swelling of your throat, lips, face, or tongue. This can also make it necessary to get emergency medical care.

Vistaril Drug Interactions

Because Vistaril sedates the patient, it shouldn’t be taken with other medications that cause drowsiness. This can include allergy or cold medications, narcotic pain medications, sedatives, seizure medications (such as Dilantin), muscle relaxers, sleeping pills, anxiety medications, and depression medications (such as Zoloft). Before starting this medication, your doctor needs to know everything you’re taking, including herbs and OTC medications.

Many medications are more likely to lead to serious heart problems if you take them along with Vistaril. These include many antibiotics, heart rhythm medications, antidepressants, cancer medications, antipsychotic medications, HIV or AIDS medications, and medications to treat malaria.

Vistaril Strengths and Dosages

This medication has many forms, including tablets, capsules, an oral suspension, and an injectable solution. The tablet has strengths of 10 mg, 25 mg, and 50 mg. The capsules come in 25 mg, 50 mg, and 100 mg. The oral suspension/syrup comes in 10 mg. The injectable solution comes in 25 mg and 50 mg.

Tablets:10 mg, 25 mg, 50 mg
Capsules:25 mg, 50 mg, 100 mg
Oral suspension:10 mg
Injectable solution:25 mg, 50 mg


When prescribed to treat an itch, it’s often prescribed at the 25 mg strength three or four times a day. When it’s prescribed to help sedate a patient, it’s often prescribed at a dosage of 50 mg to 100 mg. When it’s used to treat tension and anxiety, it’s often prescribed at the 50 mg or 100 mg strength two to four times a day.

FAQs of Vistaril 

Can Vistaril cause drowsiness?

Yes. Just as with other antihistamines, this medication can cause patients to become drowsy. Knowing how this medication affects you before you drive a car or operate any other dangerous machinery is essential. Make sure that you don’t take anything else along with it, like alcohol or narcotic pain pills that can make the drowsiness even worse.

How long does it remain in the body?

This medication generally takes about 100 hours to be entirely out of the patient’s system. The half-life is around 20 hours. A medication takes around five half-lives to completely clear from the body.

How long does it take Vistaril to start working?

This medication will start working within around 15 to 30 minutes. It can treat skin allergy problems like itching for four days. The drowsy effect of the drug can last anywhere from four to six hours. If this medication makes you tired, you may need to wait that long to drive.

Can Vistaril help you sleep?

When sleeplessness is caused by anxiety and tension, this medication may be prescribed for all of these problems. It has a sedating effect that can help people to sleep. It’s often given to people before surgery to make them sleepy and relaxed.

Can Vistaril be taken long-term to treat anxiety?

It’s generally meant for short-term use for anxiety that lasts less than four months. When it’s prescribed for long-term use, this is an off-label use. There haven’t been any studies about Vistaril’s long-term effects. There is some suggestion that there may be a connection between this medication and dementia, especially when older people take it.

When can I drink alcohol again after taking Vistaril?

If you are no longer taking this medication, you need to wait anywhere from 48 to 60 hours before you drink any alcohol. This is especially true if you’re taking the Vistaril to treat your anxiety. When you drink alcohol, it can cause anxiety to get worse.

Can you take this medication while pregnant?

No, it should never be taken during pregnancy. This is especially true for pregnant women in their first or second trimesters. This medication has been shown to cause congenital disabilities when it’s taken during pregnancy.

Can you take this medication with HIV or AIDS medications?

No, it generally shouldn’t be taken with those medications. This can cause patients to develop a heart problem or cause an existing one to worsen.

Is this an expensive medication?

No, this drug has been around for many years, and many companies make generic versions of it. That has led to the price decreasing over the years until it is reasonable.

Do these come in tablets or caplets?

It comes in both forms: an oral syrup and an injectable medication.

Will Vistaril help with an itchy rash?

This is one of the primary uses of this drug. An antihistamine can block some of the histamines released due to an allergy. This can cause a rash to get better or go away.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

Product was successfully added to your cart!