Xolair is the brand name for a drug called omalizumab. It treats nasal polyps, chronic hives, and allergic asthma. It’s generally administered in a healthcare setting by a health practitioner. If the medication is to be administered at home, they will teach you how to use it. This medication is a monoclonal antibody.

This medication is often used to prevent patients from having asthma symptoms. It’s often used after trying other medications that haven’t worked well. Xolair works by lowering the amount of substances released by your body that cause the symptoms of allergies. This lowers the amount of airway inflammation so that you can breathe more easily. This medication also reduces the amount of itching patients have. It’s not for use when you have a sudden asthma attack.

This medication can be used to reduce the risk of allergic reactions such as anaphylaxis. It can be used by people aged one year and older with Ig-E-mediated food allergies. Because Xolair minimizes the amount of inflammatory substances the body releases in response to an allergen, it can decrease the amount of allergic response the body develops.

When it’s prescribed for persistent asthma, it’s used in patients who are aged six and older who have asthma that isn’t kept under control by using inhaled corticosteroids. When it’s used for patients with nasal polyps, it’s used in patients aged 18 and up when nasal corticosteroids don’t work well.  For those with chronic hives with no known cause, it’s prescribed for people aged 12 and over if other medications haven’t worked well.

Xolair Precautions and Warnings

When taking this medication, patients should still avoid all the foods they’re allergic to. This medication isn’t for emergency treatment when an allergic reaction, including an anaphylactic reaction. It can’t be used for sudden breathing problems.

It’s possible to have a severe allergic reaction to this medication, and this can include life-threatening reactions. This can happen just after the drug is injected, or it could be several hours afterward. In some patients, an allergic reaction occurs after they’ve been taking this medication for a year or more. If you have any symptoms of an allergic reaction, you need emergency medical care. These include flushing, fear or anxiety, hives, chest tightness, difficulty breathing, dizziness, wheezing, rash, shortness of breath, weak or fast heartbeat, or swelling of the throat, lips, face, or tongue.

Often, asthma is treated with several different medications (such as Trelegy or Breo). It’s essential to use all of them as they are prescribed. Don’t change your medication schedule or your dosage without talking to your doctor. If your asthma drugs stop working as well as they did before, tell your doctor right away. Xolair often doesn’t improve symptoms right away. It’s essential to keep getting the injections as prescribed so that symptoms will get better over time.

This medication can increase a patient’s risk of developing breast, salivary gland, prostate, or skin cancer. While you take it, you may also have a higher chance of developing a parasite infection, such as worms, if you go to areas where these infections regularly occur. Consult with your doctor to find out what you should watch out for and how such an infection could be treated if it happens.

If you’re pregnant or are trying to conceive, tell your doctor right away before you start this medication. It’s unknown whether there are any risks to the baby while taking this medication. It’s also unknown whether it can harm a baby who is breastfeeding. Talk to your doctor about breastfeeding and whether you can continue to do so while taking this medication.

Don’t take Xolair if you are allergic to omalizumab or any of the medication’s inactive ingredients. You can talk to your doctor or pharmacist about the inactive ingredients in each dose. Make sure to tell your doctor if you have:

  • Symptoms that indicate an infection, such as fever, general unwell feeling, or swollen glands
  • A parasitic infection such as hookworm, giardia, pinworm, malaria, and others
  • Cancer, either currently or in your past
  • A health history that includes a stroke or heart attack
  • You’ve ever had an anaphylactic reaction to anything
  • You’re getting allergy shots
  • You are allergic to latex, dyes, hamster proteins, foods, other medications, or preservatives

Xolair Side Effects

If you experience for quite some time, please reach out to your prescriber or seek attention of a healthcare professional.

Common Side Effects

  • Nosebleeds
  • Rash
  • Leg or arm pain
  • Headache
  • Fever
  • Ear infection or ear pain
  • Bone fractures
  • Joint pain
  • Nausea and vomiting
  • Stomach pain
  • Dizziness or a tired feeling
  • Diarrhea
  • Injection site irritation, pain, swelling, or bruising
  • Signs of a cold like sneezing, sore throat, stuffy nose, cough, etc.

Severe Side Effects

  • Trouble breathing
  • Watery of severe diarrhea
  • Tingling or numbness in your legs or arms
  • Nausea or vomiting that is chronic
  • Rash, muscle pain, and fever a couple of days after getting the medication
  • Symptoms of an ear infection such as ear pain, ear drainage, fever, trouble hearing
  • Symptoms of a heart attack such as pain that spreads to your shoulder or jaw or chest pressure or pain
  • Symptoms that you have a blood clot, such as coughing up blood, sudden weakness or numbness, redness or swelling in a leg or arm, or having trouble with speech or vision

FAQs of Xolair

Can you take this medication while pregnant or breastfeeding?

We don’t have data about any potential risks for pregnant or nursing mothers. It hasn’t been studied, so there may be risks. We also don’t know whether it passes into breast milk. Talk to your doctor about the possible risks and benefits of the medication.

Can you drink alcohol while taking Xolair?

There is no known interaction between alcohol and this medication. However, it’s possible for this medication to cause dizziness, and alcohol consumption could make this worse.

Does this medication have to be refrigerated?

Yes, the pre-filled syringes have to be refrigerated. Never freeze this medication.

Can I take this medication if I have cancer?

Generally, it isn’t prescribed for those who have cancer. However, a doctor might make an exception if it’s clearly needed.

Can this medication cure asthma?

No, but it can work when used consistently to prevent asthma problems when a patient has allergic asthma.

Is this a rescue asthma medication?

No, it isn’t used for stopping asthma attacks. It also doesn’t start working right away. It takes time for it to begin reliving asthma symptoms.

Can this injection give you a cold?

It can cause cold-like symptoms in some people. You may get a stuffy nose, cough, fever, and more.

Can this medication interact with what I’m taking?

There are no known drug interactions with this medication. It’s still essential, however, to tell your doctor about everything you take.

Can this medication cause allergic reactions?

Yes, it’s rare, but some patients have an allergic reaction. They may experience shortness of breath, difficulty breathing, swelling in the mouth or face, and other signs of a response.

What is the cost of Xolair in America?

The price of this medication depends on the place that fills the prescription and the strength of the prescribed medication. A dose of the 150 mg/mL strength generally costs about $1,500.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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