Durezol is categorized as a corticosteroid medicine. This medicine prevents the release of inflammatory substances within the body, specifically to the eye. Durezol is used to treat anterior uveitis, which is inflammation that impacts the front part of your eye. It may also be used for inflammation following cataract surgery. As a topical anti-inflammatory, the ophthalmic treatment is applied to the eye, reducing inflammation and associated pain.

Precautions and Warnings with Durezol

Durezol is commonly prescribed to treat eye conditions that cause inflammation and pain. It may also be referred to as difluprednate ophthalmic emulsion. You should talk to your doctor about any allergies or if you are allergic to this medication. The product does contain inactive ingredients so being familiar with those will be important.

Discuss your medical history with your doctor, as well as any medications, over-the-counter drugs, or herbal remedies that you may be using. Be sure to speak to your doctor about any eye infections both current and past as well as any history of glaucoma or cataracts.

When the medicine is applied, your vision may be temporarily flurry so you should avoid driving or using machinery until your vision clears and it is safe to do so. If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor and use Durezol only as needed.

When using the dropper, take measures to keep it safe and uncontaminated. Do not allow the dropper to touch any other surface or your hands. Any contamination or bacteria could lead to an infection in your eye that could cause serious damage.

Do not use while wearing contact lenses. Before wearing contact lenses, get them approved by your doctor. If your symptoms do not start to improve within 2 days of treatment, consult with your doctor.

Durezol Side Effects

The most common side effect experienced with Durezol is blurry vision. This typically resolves itself, but if the effects were to get worse or not go away, you would need to speak with your doctor quickly.

Take the medication exactly as prescribed and no longer or shorter. Using this medication irregularly or for an extended period could cause a fungal infection. If you do experience any side effects or you notice symptoms that do not go away quickly, contact your doctor immediately.

Common Side Effects

Irritation and blurry vision are common side effects. However, if you experience them long-term or they do not resolve, you need to call your doctor right away.

These are the most common side effects associated with Durezol:

  • Eye pain
  • Eye swelling
  • Eye Discharge
  • Redness of the eye
  • Discomfort from bright light
  • Changes or loss of vision

Allergic Reactions

If you have symptoms that could be signs of an allergic reaction, reach out immediately to your doctor. These are signs of allergic reactions:

  • Rash
  • Itching
  • Swelling
  • Severe dizziness
  • Trouble breathing

Drug Interactions with Durezol

Certain medications, particularly other corticosteroids, may interact with Durezol or impact the safety and effectiveness of the medicine. Speak to your healthcare provider about any medications you are taking, of any kind, so that a fully informed decision can be made before prescribing Durezol.

It may be necessary to stop taking certain medications while you use Durezol or to adjust the dosage to accommodate taking both medications. This will be up to your doctor to determine.

Durezol may interact with other medications in such a way that it reduces their effectiveness as well. Durezol may specifically interact with difluprednate or other nonsteroidal anti-inflammatory eye drops as well. This includes the following:

  • Diclofenac
  • Flurbiprofen
  • Ketorolac

Durezol Cost in America

Durezol is a name-brand ophthalmic eye treatment. It can be expensive without insurance. Here is a quick cost comparison for you.

Typically, a 5ml eye dropper bottle of Durezol averages about $200-$250 without insurance. If you have insurance or discounts, it may be cheaper. If you are able to use a generic difluprednate, the cost is significantly lower, ranging from $40-$80.

There are programs out there you can use to get discounts on drugs like these so be sure to check into the options to get the best price possible.

Why is Durezol So Expensive?

Eye drops and ophthalmic treatments such as this are specially made for our eyes, which require special formulation. This is one of the biggest reasons that these medications and others like them are so expensive. Durezol, in particular, is considered a name brand, which is another reason that it costs so much. They are sold at medication prices for minimal amounts because they are required to be formulated and prescribed for treatment. These drugs are not extremely common and therefore have low profit margins, leading to an increased cost.

Strengths and Dosages of Durezol

The exact use and dosage of Durezol may vary depending on the patient’s needs. However, this medication typically comes in just one size and strength. Most Durezol is sold in a 5ml bottle that is .05% strength. The bottle has an eye dropper built into it to accommodate the application of Durezol.

Dosage is different for cataract surgery or inflammation as opposed to anterior uveitis. Here is a breakdown of the dosage for these needs.

Below, is the traditional use and dosage of Durezol. However, your doctor may prescribe a different approach so be sure to follow their instructions for use. Stop using when the timeframe recommended by the doctor is complete.

Eye Inflammation/Surgical Pain24 hours following surgery, apply 1 drop to the affected eye every 4 times per day. Repeat this dosage for 2 weeks, or as long as the doctor specifies.
Endogenous Anterior UveitisApply 1 drop to the affected eye 4 times per day for 2 weeks. The doctor may adjust depending on symptoms.

Durezol Alternatives

There are some suitable alternatives to Durezol. Be sure to consult with your doctor to best understand the options available for your needs.

These are the most common choices

FAQs of Durezol

What is Durezol?

Durezol is an ophthalmic eye drop treatment typically used for pain and inflammation following cataract surgery. It can also be used to treat anterior uveitis.

How Long Does Durezol Stay in the System?

Eye drops such as Durezol remain in the system for a very short time. It could be in your system for up to 22 hours, but it will likely be much less.

How Do I Get Off Durezol?

Most doctors will use a slow taper that gradually decreases drops after the first week of use. This taper helps ensure a flare doesn’t happen when use is stopped completely. Follow your doctor’s instructions for use and tapering.

How Fast Do Durezol Eye Drops Work?

You should feel some relief within 1-2 minutes of using these drops. While you may still have some discomfort for several more days, each dose will make a difference and have a noticeable difference.

When Do I Start Durezol After Cataract Surgery?

Typically, you start Durezol 24 hours after your cataract surgery. Your doctor will provide specific instructions on timing and dosage and application. Follow these instructions carefully.

How Often Do I Take Durezol?

Most people use 1 drop 4 times per day for the first week of use. After the first week, the dosage may be reduced slightly or tapered until you can discontinue use altogether. Never take longer than the recommended timeframe.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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