Betoptic is a  part of the medication family of beta-adrenergic blocking agents used in the form of eyedrops for certain eye problems. These problems usually include chronic open-angle glaucoma or other issues that lead to high pressure inside the eye.

The medication is usually prescribed when the intraocular pressure is higher than normal. It typically works by adding eye drops to the affected eyes two times per day. This lowers the raised pressure within the affected eye by reducing fluid production.

Precautions and Warnings With Betoptic

There are several precautions and warnings for taking Betoptic. It may lead to serious health complications and some age groups are at higher risk than others.

Patients with Diabetes

Those with diabetes are at an increased risk for low blood sugar, as the beta-blocking aspect of the medication can mask the symptoms. This includes typical low blood sugar indicators such as sweating and dizziness as small amounts of the medication are absorbed into the bloodstream. This is uncommon due to the medication form being eyedrops. However, blood sugar for those with diabetes should be closely monitored for those taking Betoptic.

Overactive Thyroid

Beta-blockers such as Beptoptic may mask symptoms of hyperthyroidism, like increased heart rate. Small amounts of the drug are absorbed into the bloodstream, making it a rare occurrence with the use of eye drop doses.

Weakened Muscles

Beta-blockers like Beptoptic also cause muscle weakness commonly surrounding physical activity. This is also a rare occurrence with the use of eye drop doses as minimal amounts of the drug are absorbed into the bloodstream.

Patients with Bronchospastic Disease

Those with bronchospastic disease are often advised not to take beta-blockers such as Beptoptic. This includes those with a history of asthma, COPD, or lung problems, as it may increase difficulty breathing.

Heart Failure

A few cases of patients developing heart failure while using betaxolol have occurred. Indications of this include swelling in the feet or ankles, fast or irregular heartbeat, or shortness of breath when lying down or exercising. While rare, the use of Betoptic causes an increased risk for congestive heart failure and second- or third-degree heart block.

If any of these symptoms are experienced while taking Beptoptic, a medical professional should be contacted immediately.

Betoptic Side Effects

Many possible side effects may be experienced when taking Beptoptic, ranging from common to very serious.

Common Side Effects

More Serious Side Effects (Contact Doctor)

Very Serious Side Effects (Seek Immediate Medical Attention)

  • Temporary stinging or discomfort of the eye
  • Watery, dry, itchy, or red eyes
  • Blurred vision
  • Feeling as if something is in the eye
  • Headache
  • Trouble sleeping
  • Dizziness
  • Pain, swelling, or discharge in the eyes
  • Changes in vision
  • Increased light sensitivity
  • Swelling of the ankles or feet
  • Fatigue
  • Slow or irregular heartbeat
  • Muscle weakness
  • Mood changes
  • Hair loss
  • Blue fingers or toes
  • Cold hands or feet
  • Difficulty breathing
  • Unexplained rapid weight gain
  • Chest pain
  • Weakness on one side of the body
  • Difficulties with speech
  • Confusion
  • Severe dizziness
  • Fainting


In some rare occasions, severe allergic reactions may occur. Those taking the medication should seek medical attention right away if symptoms such as rash, itching, severe dizziness, difficulty breathing, or swelling of the face, younger, or throat occur.

Betoptic Drug Interactions

There are four main drug interactions linked to Beptopic. These include:

  • Oral Beta-Adrenergic Receptor Inhibitors: may cause increased intraocular pressure on the eyes or the known effects of beta blockers throughout the body.
  • Catecholamine-Depleting Drugs: May lead to possible added effects and potentially cause low blood pressure or slow heart rate, resulting in symptoms like dizziness, fainting, or postural hypotension.
  • Concomitant Adrenergic Psychotropic Drugs: Since betaxolol is an adrenergic receptor inhibitor, caution should be used when using concomitant adrenergic psychotropic drugs.
  • Calcium Antagonists, Antiarrhythmics, and Digitalis: These interactions may lead to additive effects, including hypertension and slowed heart rate.

Betoptic Strengths and Dosages

One drop of Betaxolol hydrochloride ophthalmic suspension 0.25% is typically given to the affected eye twice per day. The amount of doses and drops per day can vary from person to person. This is sometimes done by itself or in addition to another intraocular pressure-lowering medication. These usually come supplied in 2.5, 5, 10, and 15 mL plastic ophthalmic DROP-TAINER® dispensers.

Betoptic Alternatives

There are a couple of alternatives that can be taken instead of Beptoptic. These include Latanoprost ophthalmic and Timolol ophthalmic, two medications that are also prescribed to treat glaucoma by targeting open angle, intraocular hypertension.

Other medications used to treat eye conditions that may sometimes be used as alternatives to Beptoptic include:

  • Lumigan (bimatoprost) – medication used to reduce intraocular pressure in glaucoma and ocular hypertension
  • Xalatan (latanoprost) – medication used to treat increased pressure inside the eye caused by glaucoma or other eye diseases
  • Travoprost – medication used to lower pressure in the eye for people with open-angle glaucoma or ocular hypertension
  • Brimonidine ophthalmic (Mirvaso & Alphagan) – medication used to lower pressure in the eye for people with open-angle glaucoma or ocular hypertension.
  • Dorzolamide ophthalmic – medication used to reduce pressure in the eye and is often used in combination with other eye medications to treat glaucoma and adjacent conditions
  • Dorzolamide/timolol ophthalmic – a combination medication that contains dorzolamide and timolol used to lower pressure in the eye for those suffering from open-angle glaucoma or ocular hypertension

Frequently Asked Questions About Betopic

Are there other methods for taking Betoptic?

Betopic is currently only prescribed in the form of eye drops. There are no oral or injectable doses available. Those taking the drug should not consume it. Instead, they should proceed according to the instructions written on the prescription label the medication should also be shaken before use and handled with clean hands. The tip of the eyedropper should not touch the eye or any other surface. Eyes should be closed for a few moments after application. Followed by gently applying pressure to the corner of the eye for an additional brief moment.

What happens if I miss a dose?

If a dose of Betoptic is missed, it should be taken as soon as possible. If it is almost time for the next, the missed dose should be skipped and the schedule should be proceeded with as normal.

Is Betoptic safe during pregnancy?

Although there have not been a lot of tests done yet studying the effect of Betoptic during pregnancy, results from some animal studies have shown it has the potential to harm unborn children. Before taking any medication during pregnancy, it is best to talk with a doctor about whether or not it is safe and what the correct dosage should be.

What is the Cost of Betoptic in America?

A 10mL supply of Betoptic S ophthalmic suspension 0.25% usually costs around $352.84 depending on the pharmacy it is purchased from. Some coupons, rebates, savings/copay cards, trial offers, or free samples may be available. There is currently no generic version available within the United States

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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