Trintellix is an antidepressant medication used to treat depression in adults. Trintellix is classified as an atypical antidepressant.

Precautions and Warnings with Trintellix

Please have conversations with your doctor to determine if Trintellix is right for you. If you have other medical conditions including, but not limited to the following, Trintellix might not be the option.

  • Suicidal Thoughts or Behavior: Trintellix may increase your risk of suicidal thoughts or behavior in those under the age of 25. New or worsening suicidal thoughts or behavior in the first few months or duration of taking Trintellix should be disclosed with your doctor.
  • Serotonin Syndrome: A life threatening, but rare, condition named serotonin syndrome is possible. This is when there is too much serotonin in your brain mixed with other serotonin medications. Please speak to a doctor if you take other medications for mental health or pain medications before being prescribed Trintellix.
  • Bipolar Disorder: Do not take Trintellix alone when you are diagnosed with bipolar disorder. Your doctor should be aware if your or a family member has bipolar disorder to know that treatment plan is best for you.
  • Sexual Problems: Trintellix may cause problems with ejaculation, erectile dysfunction, lower sex drive, and delayed or no orgasms.
  • Pregnancy or Breastfeeding: If you are pregnant, may be pregnant, or planning a pregnancy, please speak with your doctor about Trintellix if it is right for you. If you are breastfeeding or plan to breastfeed please speak to your doctor if Trintellix is right for you or an alternative plan of feeding your child – it can be passed into breast milk.

Side Effects of Trintellix

If you begin taking Trintellix and experience any reaction such as swelling of the face, throat, or mouth please seek medical attention immediately. If you begin taking Trintellix and you are worried about the side effects you begin experiencing, please contact your doctor to speak about it.

Severe Side Effects

  • Suicidal Thoughts or behavior
  • Serotonin syndrome
  • Low levels of sodium
  • Serious bleeding

Mild Side Effects

  • Itching
  • Sexual Dysfunction
  • Abnormal Dreams
  • Excessive Gas
  • Constipation
  • Vomiting
  • Dry Mouth
  • Dizziness
  • Diarrhea
  • Nausea

Drug Interactions with Trintellix

Trintellix might interact with other medications you are prescribed, supplements you take, or herbal medications. Please consult your doctor about medications you are prescribed or medications you take to see if Trintellix will have an interaction. If you are taking any of the following medications, please speak with your doctor about taking them in conjunction with Trintellix.

What are the Strengths and Dosages of Trintellix?

Trintellix comes in the form of a tablet that is disintegrating. Depending on age and what Trintellix is being prescribed for, the lowest dosage is 5mg and goes up to 20mg. Typically you begin at 10mg daily and work up to 20mg. This depends on other medications you are taking in conjunction. Speak with your doctor about when you should be taking your Trintellix, how often, and when.

FAQs of Trintellix

What is Trintellix used for?

It is used to treat depression in adults.

When will Trintellix be generic?

It is estimated a generic version will become available by 2027.

How long does Trintellix take to work?

You may begin seeing effects in as little as two weeks, but may take up to four weeks or longer.

How long does Trintellix stay in your system?

It takes about two weeks to clear your body from Trintellix.

How long does a Trintellix withdrawal last?

A withdrawal can last up to two weeks or longer.

What type of antidepressant is Trintellix?

Trintellix is an atypical antidepressant.

How to wean off Trintellix?

Consult your doctor about tapering off Trintellix. You will begin by slowly lowering your dose and frequency of taking Trintellix.

Should you drink alcohol while taking Trintellix?

Alcohol increases the nervous system side effects of Trintellix. You should avoid or limit the use of alcohol while taking Trintellix.

What class is Trintellix?

Trintellix is a Selective Serotonin Reuptake Inhibitor.

What happens if you stop taking Trintellix?

If you suddenly stop you will experience symptoms of withdrawal.

What should you avoid while taking Trintellix?

Avoid heavy drinking, drugs that interact, and other concerning activities. Please consult with your doctor for full advice on what you should avoid while taking Trintellix.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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