Latuda is a second-generation antipsychotic medication. It is considered to be an atypical antipsychotic. The drug was first approved for schizophrenia treatment in 2010 and later for bipolar depression in 2013. The drug is also prescribed sometimes off-label for depression, bipolar II disorder, obsessive-compulsive disorder (OCD), anxiety, and insomnia treatment.

Latuda contains the active ingredient lurasidone. This atypical antipsychotic targets serotonin receptors more strongly and dopamine receptors less strongly than typical antipsychotics. It blocks specific chemical receptors in the brain and impacts neurotransmitter levels like dopamine, acetylcholine, noradrenaline, and serotonin.

Latuda Precautions and Warnings

Latuda may make patients drowsy or dizzy after taking the drug. Alcohol or cannabis may increase these effects and should be avoided. Those taking Latuda should proceed with extra caution when driving, using machinery, or doing any other task requiring alertness.

Those taking Latuda are more susceptible to getting heat stroke as it decreases sweating. Those taking the drug should stay hydrated and avoid activities or weather that may cause them to overheat. Headache, dizziness, persistent fever, and mental or need changes are all signs that indicate medical attention is needed right away. The likelihood of these symptoms is increased in older adults and may increase the risk of falling.

Symptoms are rare but may occur for infants born after their mothers have taken Latuda during the last three months of pregnancy. These symptoms may include stiffness, shakiness, drowsiness, constant crying, or feeding or breathing difficulties. A doctor should be told right away if the baby experiences any of these symptoms, especially during the first month after birth. It is not known if this Latuda passes into breast milk. A doctor should be consulted before breastfeeding.

Studies have found that while rare, there have been some cases where Latuda has worsened depression or other mood symptoms. If this is the case, a doctor or healthcare professional should be notified right away. Do not stop taking Latuda without instructions from a doctor or healthcare provider.

Do not take Latuda if you are allergic to any of its ingredients. Patients consult with their doctor or healthcare provider prior to starting Latuda if they or anyone in their family have a medical history of:

  • Kidney problems
  • Liver problems
  • Stroke
  • Breast cancer
  • Diabetes
  • Obesity
  • Low blood pressure
  • Seizures
  • Low white blood cell count
  • Dementia
  • Trouble swallowing
  • Sleep apnea

Latuda Side Effects

Latuda has a range of severe and common side effects.

Common Side Effects

Latuda has many common side effects that do not usually require medical attention. These include:

  • Drowsiness
  • Nausea
  • Restlessness
  • Runny or stuffy nose
  • Trouble sleeping
  • Weight gain

Severe Side Effects

Latuda has some severe side effects that require immediate medical attention. These include:

  • Skin rash
  • Itching
  • Hives
  • Swelling of the face or throat
  • Hyperglycemia
  • High fever
  • Stiff muscles
  • Increased sweating
  • Fast or irregular heartbeat
  • Confusion
  • Unexpected breast tissue growth
  • Discharge from the nipple
  • Change in sex drive or performance
  • Irregular menstrual cycle
  • Infection
  • Fever
  • Chills
  • Cough
  • Sore throat
  • Low blood pressure
  • Dizziness
  • Feeling faint or lightheaded
  • Vision changes
  • Pain or trouble swallowing
  • Seizures
  • Stroke
  • Suicidal thoughts
  • Worsening mood
  • Increased depression
  • Uncontrolled body movements
  • Muscle spasms
  • Tremors
  • Loss of coordination
  • Restlessness
  • Shuffled walking

Drug Interactions with Latuda

Patients taking Latuda should also avoid grapefruit or grapefruit juice, as it may enhance the side effects of the medication.

There are many possible drug interactions with Latuda. These include:

Strengths and Dosages of Latuda

Latuda is available in a variety of strengths and doses depending on the age of the patient and what it is being used to treat.

ConditionAge GroupStarting DoseMaximum Dose
Schizophrenia18 years or older40 mg once daily160 mg per day
Schizophrenia13-17 years old40 mg once daily80 mg per day
Bipolar Depression18 years or older20 mg once daily120 mg per day
Bipolar Depression10-17 years old20 mg once daily80 mg per day

Cost of Latuda in America

Latuda costs around $1,503 for a supply of 30 tablets without any insurance or additional coupons. This is the average cost for 20 mg, 40 mg, 60 mg, and 80 mg strength tablets. The average cost of 120 mg strength tablets is $2,239 for a supply of 30 tablets without any insurance or additional coupons.

Why is Latuda So Expensive?

Latuda is a name-brand drug for lurasidone. Name-brand drugs are more expensive than generic variations. Latuda is also available in very high strengths, which may increase the cost.

Latuda Alternatives

Latuda has many possible alternatives. There is a generic variation of Latuda called “lurasidone,” which may be used as a cheaper alternative. Alternatives include:

Latuda FAQs

What is Latuda used for?

Latuda is used for treating certain mental/mood disorders. These include schizophrenia and depression associated with bipolar disorder.

How long does it take for Latuda to work?

Some patients may respond to Latuda in 1 to 3 weeks. However, the full benefits of the medication may take up to 6 weeks to fully experience.

How long does Latuda stay in your system?

Latuda takes approximately 2 to 4 days to fully leave the body’s system.

How to wean off Latuda?

Abruptly stopping antipsychotic medications like Latuda increases withdrawal symptoms and the likelihood of relapsing. To wean off Latuda, a doctor may make slow and careful micro-adjustments to the medication to begin a more gentle tapering process.

What happens when you stop taking Latuda?

Symptoms may worsen, or there may be unwanted side effects if you stop taking Latuda. Quitting antipsychotics like Latuda may also cause withdrawal-like symptoms. These include symptoms such as nausea, diarrhea, restlessness, and uncontrolled muscle movements.

How long does it take for Latuda to leave your system?

Latuda takes approximately 2 to 4 days to fully leave the body’s system. Some side effects may take longer to go away than others.

Should you take Latuda with or without food?

Latuda should be taken with at least 350 calories to ensure the correct absorption. Grapefruit or grapefruit juice may enhance the effects of Latuda and should not be consumed while taking the medication.

When is the best time to take Latuda?

Latuda can be taken at any time of day as long as it is taken with at least 350 calories of food. However, it should be taken at the same each day, whether that is morning, evening, or at night.

Can I drink alcohol while taking Latuda?

No, the combination of alcohol and Latuda may result in impaired motor function or impaired cognitive abilities. This can increase the likelihood of accidents, injuries, or other harmful outcomes.

Does Latuda make you sleepy?

Yes, drowsiness or sleepiness is a common side effect of Latuda.

Does Latuda cause weight gain?

Yes, Latuda can cause weight gain. However, it has been found to be less likely to cause significant weight gain compared to other atypical antipsychotics.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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