Prucalopride is a serotonin receptor agonist that’s used to treat constipation. This tablet should be taken orally around the same time each day. Adults who have struggled with constipation for at least three months – and not as a result of prescription drugs or a disease – can take prucalopride for relief.

People who are experiencing constipation as a result of prescription drugs or a disease should not take prucalopride. Prucalopride is designed for use after other laxatives to treat constipation have not rendered success.

This medication works by increasing the digestive system’s amount of muscle contractions. With more muscle contractions, the body’s bowel movements also increase. In turn, a person facing constipation experiences relief.

Precautions and Warnings with Prucalopride

Before you begin using prucalopride, you should let your doctor know about any allergies or medical conditions you have. You should also let your doctor know if you’re currently taking medication(s), are planning to take medication(s), pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.

Prucalopride should only be taken by adults, as its effectiveness and safety in children has not been studied or confirmed. If you become pregnant while taking prucalopride, you should immediately inform your doctor.

The following factors could impact how your body responds to prucalopride and you should discuss them with your doctor accordingly:

  • Mental health challenges
  • Bowel inflammation
  • Liver problems
  • Abnormal heart rhythm
  • Kidney problems
  • Pregnancy

Prucalopride Side Effects

Prucalopride impacts the nervous system and, like all medications, comes with the risk of side effects.

Mild Side Effects

Mild side effects may lessen over time as your body gets used to prucalopride. Contact your doctor if the following side effects persist:

  • Fatigue
  • Dizziness
  • Stomach pain
  • Nausea
  • Headache
  • Diarrhea
  • Gassiness

Severe Side Effects

If you notice severe side effects after taking prucalopride, you should let your doctor know right away. If you believe you’re suffering from a medical emergency, you should immediately contact 911. Most people on prucalopride do not experience severe side effects.

Severe side effects of prucalopride include the following:

  • Heart palpitations
  • Depression
  • Facial/oral swelling
  • Kidney problems
  • Worsening digestive problems
  • Hives
  • Shortness of breath
  • Rectal bleeding
  • Abdominal pain

Drug Interactions with Prucalopride

Before taking prucalopride, you should let your doctor know about any herbs, supplements, vitamins, or medications that you’re on or planning to go on.

Prucalopride may interact with the following drugs:

Strengths and Dosages of Prucalopride

Prucalopride comes in 1mg and 2mg forms. The standard adult dose is 2mg to be taken once per day. Senior adults may be advised to take 1mg per day.

This medication should be taken at the same time each day. It can be consumed with either food/drink or on an empty stomach. If you forget a dose of prucalopride, you should take this dose as soon as you remember. If it is almost time for your next dose, you should take your next dose.

Do not take two doses of prucalopride at once to make up for a missed dose. Taking an extra dose could lead to worse side effects from the medication.

Prucalopride Alternatives

There is currently no generic version of prucalopride. However, other alternatives to this medication are available. These alternatives include the following:

FAQs of Prucalopride

What is Prucalopride?

Prucalopride is a prescription medication and serotonin receptor agonist designed to help adults who’ve struggled with constipation for at least three months and not as a result of a disease or medication.

How does Prucalopride work?

Prucalopride works by boosting the amount of ongoing muscle contractions in the digestive system. This then leads to more bowel movements.

How do I take Prucalopride?

Prucalopride should be taken orally and one time per day.

What time of day should you take Prucalopride?

Prucalopride should be taken at the same time each day and at a time that is easy to remember.

How long does it take for Prucalopride to start working?

Many people who take prucalopride notice results within seven to 15 days. Some people taking this drug may see positive results within more or less time.

Who makes Prucalopride?

Prucalopride is made by Takeda Pharmaceuticals.

What is the cost of Prucalopride in America (without insurance)?

A one-month supply of 2mg prucalopride costs about $559 – $653 without insurance at most pharmacies throughout America.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

Product was successfully added to your cart!