These enzymes are naturally created in the abdominal pancreas and allow for sugars, proteins, and fats to be appropriately digested.

In the absence of their natural creation, Creon helps to fix a pancreas that is damaged and therefore unable to generate amylase, protease, and lipase enzymes.

Creon is commonly used to counteract cases of blocked pancreatic ducts, chronically inflamed pancreas, cystic fibrosis, and exocrine pancreatic insufficiency (EPI). In cases where the pancreas has been surgically removed from the body, Creon may be used to replace vital enzymes.

Precautions and Warnings with Creon

Before you begin taking Creon , you should make your doctor aware if you have or have had any bowel disorder symptoms. You should not chew this prescription drug or hold it in your mouth for extended periods of time as it can cause oral irritation.

If you are pregnant, planning to get pregnant, breastfeeding, or planning to start breastfeeding, you should inform your doctor before you begin Creon .

Children who take Creon may not grow at a normal rate. If this happens, you should inform your child’s medical provider immediately.

If you’ve had any of the following medical complications, you should let your doctor know before taking Creon :

  • Gout
  • Hyperuricemia
  • Diabetes
  • Kidney disease
  • Scarred or blocked intestines
  • Lactose intolerance
  • Pork protein allergy
  • Problem with swallowing pills

Creon Side Effects

Creon replaces pancreatic enzymes and may come with a range of various side effects.

Mild Side Effects

If you notice mild side effects after starting Creon , they may go away as your body gets used to this medication. If the following side effects continue on, let your doctor know:

  • Stomach/abdominal pain
  • Dizziness
  • Sore Throat
  • Runny nose
  • Blood sugar changes
  • Rectal itching
  • Unusual bowel movements
  • Diarrhea
  • Gassiness
  • Vomiting

Severe Side Effects

If you begin to experience severe side effects after taking Creon , be sure to immediately inform your doctor. In cases of a medical emergency, contact 911 right away. Severe side effects from Creon are not typical.

Severe side effects from Creon can include the following:

  • Facial and/or mouth swelling
  • Joint swelling/pain
  • Hives
  • Breathing problems

Drug Interactions With Creon

Before you begin taking Creon  you should let your doctor know about any vitamins, herbs, or over-the-counter medications that you’re on or planning to start taking. These can interact with Creon .

Creon may interact with additional substances. You should let your doctor know if you’re taking any of the following substances:

Strengths and Dosages of Creon

Creon is available in 500 – 2,500 lipase units/kg of your body weight. Each person’s dose will vary, as doctors prescribe Creon doses depending upon each person’s weight, fat level, and the content of their daily meals.

This drug will be prescribed with the assumption that a person is consuming three meals each day, along with two or three snacks. No person will be prescribed Creon that surpasses 10,000 lipase units/kg of their body weight.

Creon should not be taken on an empty stomach and should be taken with a snack or meal. Do not take more or less Creon than prescribed. Do not break, split, chew, or crush Creon. This medication should be swallowed whole.

Creon Alternatives

There is not a generic version of Creon. It only exists as a brand-name drug, but the following alternatives to Creon exist:

  • Lactacyd
  • Zenpep
  • Viokace
  • Pertzye
  • Pancreaze
  • Pancreatin

FAQs of Creon

What is Creon?

Creon is a prescription drug and a collective combination of amylase, protease, and lipase enzymes.

How long does it take for Creon to work?

Creon has been known to show positive results within eight to 12 weeks. Some people taking creon may see changes in more or less time.

How long does Creon stay in your system?

Creon replaces pancreatic enzymes and should remain in your system for a lifelong period. Contact your doctor if you have further questions.

What foods should you avoid taking with Creon?

Greasy or fatty foods may be harder for your body to digest when you’re taking creon.

When do I take Creon?

Creon should be taken as you begin to eat each meal or snack.

Can I drink alcohol while taking Creon?

Alcohol can hurt your pancreas. It is not recommended to drink alcohol while taking creon.

Can I take Creon while I am pregnant?

Your doctor can confirm whether or not it is safe to take creon while pregnant.

When will Creon go generic?

There is no available generic brand of creon.

Who manufactures Creon?

Creon is manufactured by Viatris Inc.

What happens if you take too much Creon?

Taking too much creon can cause greater amounts of uric acid in the blood and fibrosing colonopathy.

What is the cost of Creon in America (without insurance)?

A 100-capsule supply of creon costs roughly $876 without insurance at most pharmacies across the United States.

Why is Creon so expensive?

Creon is expensive because it is a brand-name drug and because of the extensive testing and research that went into this medication before it hit the market.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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