The drug Vivelle is an estrogen medicine. It’s used in hormone replacement therapy (HRT) and acts as a conjugated equine estrogen (CEE).

The majority of women take Vivelle-dot patches to treat the symptoms of menopause. This drug alleviates these symptoms such as hot flashes and vaginal dryness. It is also used to treat burning and irritation of the vagina. These symptoms are caused by a deficiency of estrogen. This drug replaces estrogen in a woman’s body who has estrogen deficiency.

Precautions and Warnings with Vivelle

These are the most important precautions for Vivelle-dot patch users:

  • Do not take the Vivelle dot patch if you are pregnant. If you are pregnant, don’t use Vivelle. If you get pregnant while using the Vivelle-dot patch, concern your doctor immediately as usage of Vivelle-dot increases the risk of developing a condition that might lead to uterine cancer.
  • Do not smoke when you are taking a Vivelle-dot patch. Smoking and using Vivelle together can have some serious effects on your body because there is a risk of increasing blood clots. Smoking damages the blood vessel walls and makes blood more likely to clot. Estrogen that is present in Vivelle happens to do the same. It can be a deadly combination.
  • Do not use this patch if you have any kind of allergies. It is advised by doctors to not use this patch if you have any kind of allergies.
  • Do not share this medicine. If a medicine is used for hormone therapy replacement, then it is only best not to share it with anyone else.
  • Avoid using estradiol to prevent heart disease. Estradiol is a kind of estrogen, a sex hormone in females that is necessary for many functions in the body. Some women suffer from estrogen deficiency, and they take drugs like Vivelle-dot to treat their symptoms of menopause. Vivelle should never be used to prevent heart disease as it increases the risk of blood clots.

Vivelle Dot Patch Side Effects

If you are experiencing any side effects and believe you should seek medication attention, please do so.

Common Side Effects

  • Skin irritation at the application site
  • Headache
  • Backache
  • Cold symptoms (stuffy nose, sore throat)
  • Vaginal changes (itching, discharge, bleeding)
  • Digestive issues (bloating, cramps, nausea)
  • Breast tenderness
  • Hair loss (scalp)
  • Fluid retention (swelling, weight gain)

Serious Side Effects

If you are having symptoms like severe nausea and vomiting that won’t subside, mental health problems like depression or memory loss, feeling lumps in your breast, irregular vaginal bleeding with severe abdominal pain, skin and eyes turning yellow due to jaundice, dark-colored urine, swelled hands, feet, or ankles along with increased thirst and urination. This indicates various underlying conditions and needs a proper diagnosis from healthcare.

Signs of Allergic Reaction

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, throat

Signs of Blood Clots

Sudden severe headache, along with chest pain might spread to your jaw or left arm. These, along with unusual sweating, could be signs of a heart attack. Weakness or numbness on one side of the body, confusion, slurred speech, and vision problems could indicate a stroke. Leg pain, redness, and swelling could be a blood clot. Tingling, weakness, and numbness in limbs might point to nerve damage.

Additional Serious Side Effects

  • Heart attack symptoms (chest pain, pressure, nausea, sweating)
  • High blood pressure symptoms (severe headache, blurred vision, anxiety)
  • Stroke symptoms (sudden numbness, weakness, slurred speech, vision problems)
  • Blood clot symptoms (vision loss, chest pain, shortness of breath, coughing up blood, leg pain)
  • Stomach swelling/tenderness
  • Jaundice (yellowing of skin/eyes)
  • Unusual vaginal bleeding/pelvic pain
  • Breast lumps
  • Memory problems/confusion
  • High blood calcium symptoms (nausea, vomiting, constipation, increased thirst)

Drug Interactions with Vivelle

Vivelle-dot patch affects how your body processes other drugs. Also, different drugs may change the way your body uses the Vivelle-dot patch. Make a list of all the drugs you intake and share it with your pharmacist and doctor. Avoid stopping and changing the dose of your medicines without a prescription. Avoid using this drug when you’re breastfeeding since the Vivelle-dot patch can decrease milk quality and even pass into breast milk. This drug may cause disturbance in some lab tests, leading to false results. Always tell your doctor about using this medicine beforehand.

In general, the Vivelle-dot patch is known to interact with these medicines.

  • Anastrozole
  • Exemestane
  • Letrozole
  • Fezolinetant
  • Fulvestrant
  • Ospemifene
  • Raloxifene
  • Tamoxifen
  • Toremifene
  • Tranexamic acid

Cost of Vivelle in America

The price of a Vivelle dot patch depends on the dosage. You can get a pack of 8 patches from a price range of $171-$212.

Why is Vivelle expensive?

Vivelle is a brand-name drug, meaning the manufacturer underwent rigorous testing to prove its safety and effectiveness. This extensive research and development process is expensive, and the manufacturer can recoup those costs by initially selling it as a brand-name medication. Vivelle is a patch, which delivers medication through the skin rather than orally. This unique delivery system may involve additional technology or manufacturing processes, potentially adding to the cost.

Strengths and Dosages of Vivelle

Vivelle-dot patch is usually available in five strengths:

StrengthEstradiol Dose
0.025 mg/day0.025
0.0375 mg/day0.0375
0.05 mg/day0.05
0.075 mg/day0.075
0.1 mg/day0.1

It is totally up to your doctor or health expert to prescribe the right strength for you after considering your symptoms and medical history.

Vivelle Alternatives

Vivelle is available primarily as a name-brand drug. However, you can also buy conjugated estrogens (CEs) other than Vivelle if they cost less than the branded version. Some approved alternatives for Vivelle are:

Vivelle FAQ

Where to apply Vivelle?

Vivelle-dot patches can be applied to the stomach or buttocks. You will need clean and dry skin. All you have to do is press the patch with firm hands for at least 10 seconds. Change spots every time you use a new patch. Avoid using the same skin area twice within a week. If your patch is falling off, try to stick it back into place. If it is not sticking, use a new patch on a new area, and try not to change your patch removal timing.

When will Vivelle go generic?

In December 2014, Mylan launched a generic version of Vivelle.

What is the lowest dose of Vivelle?

This drug is used to prevent the condition of postmenopausal osteoporosis. It is advised to start the therapy with 0.0375 mg/day twice a week. The minimum dose of the Vivelle dot patch that has proved to be effective is 0.025 mg/day.

How do you stop taking Vivelle?

You can not just stop taking estrogen patches. If you have decided to stop your hormone replacement therapy, then it can be done by reducing the dosage OF Vivelle-dot patch gradually.

Can Vivelle cause weight gain?

Yes! The swelling of different body parts and gaining weight are common side effects of the Vivelle-Dot Patch. It also causes bloating.

Can I drink alcohol while using Vivelle?

No! It is not okay to drink alcohol when you are taking hormone therapy replacement because there is a risk of alcohol bringing unfavorable health outcomes.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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