Procytox is a brand name for the medication cyclophosphamide. It is a type of cancer drug called an antineoplastic. It specifically belongs to a group of medicines called alkylating agents. This medication interferes with the DNA of cells to keep cancer cells from growing. It works on cancer cells because they grow more quickly than other types of cells.

This medication is used to treat several types of cancer, including blood cancers, lymphoma, and leukemia. It also treats small cell lung cancer, Hodgkin’s disease, neuroblastoma, soft tissue cancers such as muscle cancers, retinoblastoma, and multiple myeloma.

Precautions and Warnings With Procytox

This medication should not be taken during pregnancy because it can be harmful to the baby. Both women and men who are taking this medication should use effective birth control (such as Yaz) while taking Procytox. This should be continued for a few months after you’re finished taking this medication. Don’t become pregnant or father a baby while taking it. Talk to your doctor about effective birth control methods that might be right for you.

Procytox is passed in urine. If this medication stays inside the bladder for too long, it will irritate this organ. To keep urine containing this medication in the bladder for too long, you’ll need to drink more fluids than usual while taking it. It would help if you emptied your bladder often to keep your kidneys working well. Drinking anywhere from seven to 12 cups of fluids daily is likely needed.

When you take this medication, take it exactly as the doctor directed. This medication is taken first thing each morning so that the risk of bladder issues is reduced. If you take this medication along with some food, it can decrease the chance that you’ll have an upset stomach. It may cause you to have nausea or to vomit, but you will have to continue to take it as long as your doctor orders it. Don’t stop this medication unless your doctor tells you to. If you take a dose and vomit shortly after, you can call your doctor about whether you will take another dose or skip the dose. If you accidentally skip a dose, contact your doctor to determine what to do next. It would be best to never take a double dose to make up for a missed one.

If you are allergic to the active ingredient in Procytox, or any of its inactive ingredients, don’t take this medication. Let your doctor know if you’ve ever shown any signs of an allergic reaction to it. Don’t take this medication if you have bladder inflammation, known as cystitis, or if you have any obstructions to your urinary outflow. Don’t take it if you have any severe liver problems or serious kidney problems. You also shouldn’t take it if you have low platelet counts or a severely low white blood cell count. Don’t start this medication if you already have an active infection, especially if it’s a varicella zoster infection.

Procytox Side Effects

As Procytox interferes with the DNA of your cancer cells, it can also interfere with specific other cells. This can lead to several side effects from this medication.

Common Side Effects

Some of the common side effects you might experience include:

  • Hair loss
  • Mouth sores and other mouth irritation
  • Loss of appetite
  • Diarrhea
  • Nausea and/or vomiting
  • General unwell feeling
  • headache
  • Lowered white blood cell count leading to fever, chills, unusual fatigue, infections, and sore throat

Serious Side Effects

There are also side effects that can occur that are more serious. These side effects can be severe, and you need to talk to your doctor about them right away:

  • Skin inflammation
  • Vein inflammation
  • Confusion
  • Blood in your urine
  • Dizziness
  • Urination with pain or burning
  • Fever or chills along with hoarseness or cough
  • Injection site pain, swelling, or redness
  • Arm or leg numbness, tingling, or prickling
  • Symptoms of anemia – pale skin, shortness of breath, weakness or tiredness, dizziness
  • Symptoms of heart failure – swelling in the feet, ankles, or legs, fatigue, shortness of breath
  • Symptoms of kidney problems – decreased amount of urine, change of urine color, more urination during the night, blood in your urine
  • Symptoms of an infection – headache, severe diarrhea, weight loss, stiff neck, dizziness that lingers, shortness of breath, listlessness
  • Symptoms of liver problems – diarrhea, pale stools, dark urine, jaundice, loss of appetite, nausea, vomiting, weight loss
  • Symptoms of lung inflammation – persistent cough, fingernails or lips getting darker, feeling burning in your chest
  • Signs of low blood pressure – dizziness, nausea, fainting, blurry vision, lightheadedness, increased thirst

Drug Interactions With Procytox

This medication may interact with a number of other medications. These include:

  • Azole antifungals such as itraconazole (Sporanox), fluconazole (Diflucan), and ketoconazole
  • Allopurinol
  • Carbamazepine (Tegretol)
  • Bacillus Calmette-Guerin
  • Denosumab (Xgeva)
  • Clozapine
  • Filgrastim
  • Diuretics like indapamide, hydrochlorothiazide, and metolazone
  • Efavirenz
  • Mifepristone
  • HIV protease inhibitors like ritonavir (Norvir), indinavir, and atazanavir
  • Rifampin (Rifadin)
  • Immunosuppressant medications
  • Vaccines

Strengths and Dosages of Procytox

This medication is available as both a tablet and an injection. The tablet form is available in the strengths 25 mg and 50 mg. The injection form is available in strengths of 200 mg, 500 mg, 1,000 mg, and 2,000 mg. The dosage you get will depend on a lot of factors including the type of cancer that you have.

Tablets:25 mg, 50 mg
Injections:200 mg, 500 mg, 1,000 mg, 2,000 mg

Procytox Alternatives

There are various other drugs that are prescribed for the types of cancer treated with Procytox. These include Enhertu, Anastrozole, Tamoxifen, Ibrance, Arimidex, Exemestane, and Letrozole. If Procytox doesn’t work well for you, or it’s not well-tolerated, you could be switched to a different medication by your doctor.

FAQs of Procytox

Who makes Procytox?

It’s made by Baxter Healthcare.

When was Procytox approved for use?

It was first approved in 1959.

Can you take Procytox while pregnant?

No, this medication should not be taken during pregnancy or while breastfeeding. It presents a risk of harm to the baby.

What ages can take this medication?

It isn’t recommended for people who are under age 16.

Can this medication cause hair loss?

Yes, hair loss is a common side effect. However, hair can grow back after the medication is stopped.

Are there a lot of side effects with this medication?

Yes, there are many side effects possible such as headaches, nausea, and vomiting. Some side effects may be severe.

Why is this medication prescribed?

Procytox is prescribed to treat a number of types of cancers including small cell lung cancer and soft-tissue cancers.

How does this medication work?

It creates interference with cell DNA to stop cancer cells from growing. It affects cancer cells because they grow faster than other cells.

Why does this medication cause bladder problems?

Procytox can cause bladder problems because the medication is eliminated in urine. When urine containing this medication sits in the bladder, it can irritate this organ. Drinking a lot of fluid and urinating often can help.

Can this cause vomiting?

Yes, this is a possible side effect. If you vomit after taking the medication, call your doctor to find out what to do next.

What is the cost of Procytox in America?

The 200 mg injection form is about $163. The 25 mg tablet costs about $300 for 100 tablets. There are generics available of this medication, so the prices aren’t as high as with many other cancer drugs.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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