Flagystatin is an antifungal medication that is used for treating vaginal infections that are caused by certain fungi and bacteria mixed. There are two active ingredients in this medication. One of them, metronidazole, is used to kill the bacteria in the infection. The other, nystatin, is used to kill the fungi. Together, both of these are used to get rid of the entire infection. The bacteria is trichomonas vaginalis, and the fungus is C. albicans.

Flagystatin Precautions and Warnings

There have been some cases of severe hepatotoxicity/acute hepatic failure in patients who have Cockayne syndrome. There have been some cases of this that have resulted in death. If you have this condition, make sure that your doctor knows about it before you take this medication. It might be used in these patients when there isn’t anything else to try eliminating the infection.

One of the active ingredients in this medication, metronidazole, has been shown in studies to cause cancer in rats and mice. Therefore, this medication should never be taken unless absolutely needed and should rarely be used for an extended period.

Some patients have had local irritation from using this medication. If this happens, it may be necessary to stop taking this medication. Before you stop taking it, talk to your doctor about whether this is the best course of action.

Once this medication has been used, it’s essential to identify why the infection occurred and how to prevent it from reoccurring. This should be done so that you don’t have to use this medication over and over again.

Patients should avoid drinking any alcohol while they’re taking Flagystatin and for at least a day after they’re finished taking it. You must know how this medication affects you before you drive or do anything else dangerous. This medication can have side effects that make it too difficult to drive. Adding alcohol to this could make the symptoms even worse.

If you’ve ever taken metronidazole and had it cause liver injury, you shouldn’t take this medication. There have been some reports of severe skin problems, such as Stevens-Johnson syndrome, after taking this medication. If you have skin problems, you should stop taking the medication and ask your doctor about an alternative.

If this medication is used for a long time, it can cause fungi and bacteria resistant to the medication to get overgrown, causing a new infection.

It’s not recommended to use condoms while you’re taking this medication. It can make condoms less effective. If your period starts, you should keep taking this medication. While taking Flagystatin, don’t use any soaps or tampons with an acid pH.

For patients with chronic or active central and peripheral nervous system diseases, this medication shouldn’t be taken, especially if the condition is severe. It should also not be used by anyone with hepatic encephalopathy.

It’s known that when a pregnant woman uses metronidazole, one of the active ingredients, it will pass through the placental barrier. It hasn’t been associated with any complications, but it should be avoided at least during the first three months of the pregnancy. The nystatin portion of the medication may have risks to the baby, but we don’t know yet. There haven’t been studies to show whether it’s safe. We do know that metronidazole is passed through breast milk, so it’s not recommended that breastfeeding women take this medication.

Side Effects of Flagystatin

Many side effects may occur while you’re taking this medication. It’s important to talk to your doctor if any of them are severe or they bother you. Some effects go away after a short time on this medication. Many people don’t get any side effects at all.

If you have chest pain or seizures, call for emergency medical care. The same should be done if you have any confusion, a sudden high fever, or a stiff neck. These can be signs of meningitis. It’s also possible to have a severe skin reaction to this medication. Call your doctor immediately if you get peeling, blistering skin or a rash that is large or spreads quickly.

It’s also possible to have a severe allergic reaction to this medication. This can come with difficulty breathing, abdominal cramps, nausea and vomiting, and throat, mouth, or face swelling.

Common Side Effects

  • Dark urine
  • Headache
  • Dry mouth
  • Ringing or buzzing in the ears
  • Diarrhea
  • Changes in taste and a metallic taste
  • Constipation
  • Vaginal sensation of granules
  • Loss of appetite
  • Nausea
  • Vomiting
  • Hearing loss
  • Mild itching or burning in the vagina
  • Heartburn
  • Insomnia
  • Spinning sensation

Serious Side Effects

  • Difficulty moving
  • Flu-like symptoms
  • Confusion
  • Irrational thoughts
  • Rapid, pounding heartbeat or skipping heartbeats
  • Hallucinations
  • Signs of liver issues such as yellowing of the eyes or skin, pale stools, and dark urine
  • Signs of depression such as difficulty concentrating, weight changes, less interest in activities, sleep changes, and any suicidal thoughts

Flagystatin Drug Interactions

If you’re on a medication that interacts with Flagystatin, you may need to be taken off of it temporarily, or you may need a new dosage. Ensure your doctor knows every medication you take, including OTC ones, in case one of them would interact poorly with this medication.

Many substances can interact badly with Flagystatin. These include:

  • Lithium
  • Alcohol
  • Warfarin
  • Lopinavir
  • 5-fluorouracil
  • Barbiturates
  • Disulfiram
  • Tipranavir
  • Busulfan
  • Progesterone
  • Cyclosporine (such as Restasis)
  • Phenytoin (found in Dilantin)

FAQs of Flagystatin

Can you drink alcohol when you take Flagystatin?

No, you are not supposed to drink any alcohol throughout your treatment with this medication.

Can you use this medication while pregnant or breastfeeding?

No, it shouldn’t be used in pregnancy, especially during the first trimester. It’s not recommended that you breastfeed while taking this medication, either.

Are there any side effects from taking Flagystatin?

Yes, there can be many side effects, but most are mild and don’t bother patients very much. These can include heartburn, headaches, nausea, dry mouth, dizziness, and insomnia.

Is this an expensive medication?

No, compared to many other drugs, it’s a lower-priced option. Patients can pay about $55 or less.

Does warfarin interact with this medication?

Yes, it can interact badly. Make sure that your doctor knows you’re taking warfarin before you get prescribed this medication.

What form does this medication come in?

It comes in a vaginal ovule. An applicated is used to position the ovule inside the vagina where it can work to kill the infection.

Can you stay on this medication for a long time?

It’s usually taken for ten days and shouldn’t go past this. There are risks involved with using it for a very long time or repeatedly. If you’ve been getting a lot of infections, try to figure out what’s causing them so you can avoid them.

Does Flagystatin get rid of a vaginal bacterial infection or a fungal infection?

It gets rid of both. There are active ingredients in this medication that will kill bacteria and fungi to get rid of an infection that involves both.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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