Juluca (Dolutegravir, Rilpivirine) is a combination antiviral drug used against the Human Immunodeficiency Virus (HIV) in your body. You can be prescribed Juluca as part of a treatment plan for HIV, which causes Auto Immunodeficiency Syndrome (AIDS), but it does not cure the disease.

Your doctor or healthcare provider will only prescribe Juluca if you are successfully treated with other antiviral medications for at least six months.

Juluca contains antiretroviral drugs, such as antiretroviral dolutegravir and rilpivirine, which prevent the enzymes nurturing this virus from making copies of it in the infected cells. Dolutegravir blocks an enzyme called integrase, while rilpivirine blocks the activity of another enzyme called reverse transcriptase.

Juluca reduces the amount of HIV virus in the body by keeping it at low levels. This prevents your immune system from being affected by AIDS-related infections and diseases.

Dolutegravir and Rilpivirine Hydrochloride have been approved by the U.S. Food and Drug Authority (FDA) and are available in the market.

Precautions and Warnings with Juluca

Juluca will be dangerous for your unborn baby when taken at the time of conception or during the first 12 weeks of pregnancy.

You should use effective birth control methods to prevent pregnancy and inform your doctor or healthcare provider if you get pregnant. In this case, your name will be included in a registry that monitors the effects of HIV on your baby.

You should not breastfeed your baby if you have HIV or AIDS, as this disease can be passed to the baby through your breast milk.

You should follow the treatment plan prescribed by your doctor or healthcare provider to control the spread of HIV in your body.

A doctor will change your treatment plan with Juluca if you have these conditions:

  • Liver problems
  • Mental illness
  • Pregnancy

Juluca Side Effects

Inform your doctor immediately if you experience any of the above-mentioned symptoms while taking Juluca.

Juluca can cause these side effects:

Common Side Effects

  • Anxiety
  • Depression
  • Abnormal dreams
  • Dark urine
  • Urinary problems (decreased frequency or amount and cloudy or bloody urine)
  • Loss of appetite
  • High blood pressure
  • Abdominal pain
  • Indigestion
  • Light-colored stools
  • Gaseous stomach pain
  • increased thirst
  • Weight gain
  • Body pain
  • Nausea
  • Vomiting
  • Stomach fullness or pain
  • Swelling
  • Fatigue
  • Sleep issues
  • Trouble breathing
  • Unusual tiredness or weakness

Serious Side Effects

  • Fever
  • Sore throat
  • Swollen glands
  • Chest pain
  • Decreased appetite
  • Painful or difficult urination
  • Black, tarry stools
  • Chills
  • Cough
  • Difficulty swallowing
  • Rapid heartbeat
  • Headache
  • Painful or difficult urination
  • Skin itching, rash, or redness
  • Sores, ulcers, or white spots on the lips or in the mouth
  • Stomach tenderness
  • Stomach pain, continuing
  • Unusual bleeding or bruising

Rare Side Effects

  • Joint pain or swelling
  • Muscle aches, cramp, or stiffness
  • Difficulty in moving

Drug Interactions with Juluca

Taking Juluca and Dofetilide together can cause serious medical conditions (or even death). So, your doctor or healthcare provider will not prescribe you Juluca if you are taking more than one dose of Dexamethasone per day.

You should inform your doctor or healthcare provider about the medication that you are using before starting treatment with Juluca.

The following medicines can lower the efficacy of Juluca as well:

  • Dexamethasone
  • Dofetilide
  • Carbamazepine
  • Oxcarbazepine
  • Pantoprazole
  • Rabeprazole
  • Rifabutin
  • St John’s Wort
  • Darunavir
  • Efavirenz
  • Etravirine
  • Nevirapine
  • Atazanavir
  • Darunavir
  • Idelalisib
  • Isoniazid
  • Lumacaftor
  • Ivacaftor
  • Magnesium supplements
  • Iron supplements
  • Zinc supplements
  • Calcium supplements
  • Valproic Acid

Cost of Juluca in America

The price of Juluca sranges from$3,418 and $3,708 for a supply of 30 tablets without insurance. These prices may vary depending on the pharmacy from where you purchase Juluca.

Why is Juluca so expensive?

Juluca is expensive because it does not have a generic version. The patent laws allow just one company (i.e., the manufacturer of that particular drug) to sell it. Also, it works simultaneously with other medications and patients can be prescribed to take three pills a day which can be pretty costly.

Strengths and Dosages of Juluca

Juluca comes in pink color and oval shape with the term “SV J3T” engraved on one side. Each tablet contains 50 mg of dolutegravir and 25 mg of rilpivirine.

This medicine should be consumed once daily with a meal.

Your body weight, other medical conditions, and different drugs can affect the functioning of Juluca. It is necessary to take this medication exactly as prescribed by your doctor. You should not change your dosage without consulting with your doctor or healthcare provider.

Juluca Alternatives

You must consult with your doctor or healthcare provider before switching to these alternatives, however. Your physician can assist you in understanding the risks associated with these above-mentioned medicines.

It is important for you to purchase a drug from a trusted brand and follow the instructions of your doctor or the instructions on the label.

A doctor can interchange Juluca with these medicines:

Juluca – Frequently Asked Questions

What is Juluca?

Juluca is a pink-colored and oval-shaped medicine used to prevent the spread of HIV-1 infection among adults. It is a blend of two antiretroviral drugs i.e., dolutegravir and rilpivirine. It’s taken orally once a day with meals.

How does Juluca work?

This medicine combines the power of two antiretroviral drugs (dolutegravir and rilpivirine) that attack the virus enzymes and prevent them from affecting human cells. The second one is a non-nucleoside reverse transcriptase inhibitor that stops the virus from making copies of it.

How is Juluca taken?

Juluca is taken orally once a day with regular meals. You should not take it with certain drugs which can cause severe side effects and reduce the medicine’s efficacy.

What is the strength of Juluca?

Each tablet of Juluca contains 50 mg of dolutegravir and 25 mg of rilpivirine.

What are the side effects of Juluca?

Headache, diarrhea, and nausea are some of the common side effects of Juluca. The serious side effects are allergic reactions, liver problems, and emotional instability.

Does Juluca interact with other medications?

Juluca interacts with several other drugs, including certain antibiotics, antifungal, and seizure medications, along with St. John’s wort; as a result, patients should keep doctors or healthcare providers informed about the medicines they are taking.

Does Juluca cure HIV?

Juluca is not a cure for HIV. It suppresses this virus and controls its spread in the body. Patients must continue taking this medicine with other drugs for the rest of their lives.

How effective is Juluca?

Research has shown that Juluca has been effective in suppressing HIV-1 infection among adults who shifted to this medicine from a stable antiretroviral regimen.

Can Juluca be used during pregnancy?

Doctors don’t prescribe Juluca during pregnancy. Pregnant women should consult a doctor regarding the potential risks and benefits of the medicine or seek treatment via a different antiretroviral regimen.

Can children take Juluca?

Juluca is not approved for use in children and adolescents below 18 years of age.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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