Arnuity Ellipta is a prescription medication used to treat asthma in adults and children aged five years and older. It belongs to a class of drugs known as inhaled corticosteroids. Arnuity is specifically indicated for the maintenance treatment of asthma as a prophylactic therapy.

Arnuity Ellipta contains fluticasone furoate, which is a synthetic corticosteroid. It exerts its anti-inflammatory effects by inhibiting the release of inflammatory mediators and reducing airway inflammation. This helps to prevent asthma symptoms such as wheezing, shortness of breath, chest tightness, and coughing.

Arnuity Precautions and Warnings

Before using Arnuity Ellipta, it is essential to consider the following precautions and warnings:

  • Patient Eligibility Criteria: Arnuity is not suitable for everyone. Patients with a known hypersensitivity to fluticasone furoate or any of the excipients should not use this medication.
  • Contraindications: Arnuity is contraindicated in patients with primary treatment of status asthmaticus or acute episodes of asthma requiring intensive measures.
  • Special Populations: Special caution is advised when using Arnuity in specific patient populations, such as pregnant or breastfeeding women, pediatric patients, and individuals with hepatic or renal impairment.
  • Monitoring Parameters: Patients using Arnuity should be monitored regularly for signs of asthma control, including lung function tests and symptom assessment.

Arnuity Side Effects

If you are experiencing prolonged side effects, please speak to a healthcare professional.

Common Side Effects

Patients using Arnuity may experience common side effects, including:

  • Cold Symptoms: Such as stuffy nose, sneezing, sore throat, and sinus pain.
  • Low Fever: Accompanied by cough, wheezing, and chest tightness.
  • Hoarseness or Deepened Voice: A possible effect of the medication on the vocal cords.
  • White Patches or Sores: Inside the mouth or on the lips.
  • Headache: A common side effect that may occur during the initial use of Arnuity.
  • Nausea, Vomiting, Upset Stomach: Gastrointestinal symptoms that may occur.

Serious Adverse Reactions

While uncommon, severe adverse reactions may occur, and patients should seek immediate medical attention if they experience:

  • Weakness, Tired Feeling, Nausea, Vomiting: Particularly if accompanied by a feeling of passing out.
  • Wheezing, Choking, or Other Breathing Problems may occur after using Arnuity.
  • Blurred Vision, Tunnel Vision, Eye Pain: Any vision changes should be reported to your healthcare provider.
  • Worsening of Asthma Symptoms: If asthma symptoms worsen despite using Arnuity.
  • Blood Vessel Inflammation: Manifested by symptoms such as fever, cough, stomach pain, weight loss, skin rash, severe tingling, numbness, or chest pain.
  • Liver Problems: Indicated by upper stomach pain, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).

Arnuity Drug Interactions

Arnuity may interact with various medications. Please note this is a partial list. As mentioned, you should be able to talk to your prescriber about any and every medication you are taking.

Some notable interactions include:

Interaction CategoryExamples of Interacting Drugs
Cytokine TherapyAldesleukin
AntifungalsAmphotericin B, “Azole” antifungals (e.g., Sporanox, ketoconazole, voriconazole)
VaccinesBCG, Vaccines
HIV MedicationsHIV protease inhibitors (atazanavir, darunavir, lopinavir, ritonavir)
Enzyme ModulatorsCobicistat, Conivaptan, Hyaluronidase, Ivacaftor
Iron ChelatorsDeferasirox
Osteoporosis TreatmentDenosumab (Xgeva)
Cardiovascular MedicationsTiazac XC, Multaq, Verapamil
Herbal SupplementsEchinacea
Multiple Sclerosis TreatmentsFingolimod, Natalizumab
Grapefruit Juice InteractionGrapefruit Juice
AntibioticsMacrolide antibiotics (e.g., Biaxin, erythromycin)
Reproductive HealthMifepristone
Dermatologic MedicationsElidel
Protein Kinase InhibitorsCrizotinib, Dasatinib, Idelalisib, Gleevac
Antiepileptic MedicationsStiripentol
DiureticsLoop diuretics (e.g., bumetanide, furosemide), Thiazide diuretics (e.g., hydrochlorothiazide, indapamide)
Rheumatoid Arthritis MedicationLeflunomide
Cystic Fibrosis TreatmentXeljanz
Cancer TreatmentsTrastuzumab

Arnuity Strengths and Dosages

Arnuity comes in a variety of strengths and dosages. You must follow your prescriber’s instructions when dosing with any medication. We will only ship you the strengths and dosages your prescriber has written down on your prescription.

Available Strengths

Arnuity is available in various strengths to accommodate individual patient needs. The available strengths include:

Strength (mcg)Indication
50Suitable for certain patient populations and as a starting dose.
100A commonly prescribed strength for maintenance therapy.
200A higher strength for patients requiring more significant asthma control.

Recommended Dosages

The recommended dosage of Arnuity Ellipta depends on various factors, including the patient’s age, severity of asthma, and previous treatment regimens. Typically, the recommended dose is administered once daily in the evening.

Alternatives to Arunity

While Arnuity is an effective option for the maintenance treatment of asthma, there are alternative medications with different mechanisms of action.

Drug NameDosage
Arnuity (fluticasone furoate inhalation powder)12 years and older: 1 inhalation of 100 mcg or 200 mcg once daily; 5 to 11 years old: 1 inhalation of 50 mcg once daily
Alvesco (ciclesonide)12 years or older: 1 inhalation twice daily of 80 to 320 mcg
Asmanex HFA (mometasone furoate)12 years or older: 2 inhalations twice daily of 100 mcg or 200 mcg
Beclomethasone dipropionate HFA12 years or older: on previous bronchodilator 40 to 80 mcg twice daily, on previous corticosteroid 40 to 160 mcg twice daily; aged 5-11 years: 40 mcg twice daily
Flovent HFA (fluticasone propionate inhalation aerosol)12 years or older: 80 mcg twice daily up to a maximum dosage of 880 mcg twice daily; aged 4 to 11 years: 88 mcg twice daily
Flovent Diskus (fluticasone propionate inhalation powder)12 years or older: 100 mcg twice daily up to a maximum dosage of 1,000 mcg twice daily; aged 4 to 11 years: 50 mcg twvice daily up to a maximum dosage of 100 mcg twice daily
Fluticasone propionate HFA12 years or older: 80 mcg twice daily up to a maximum dosage of 880 mcg twice daily; aged 4 to 11 years: 88 mcg twice daily
Pulmicort Flexhaler (budesonide)18 years or older: 360 mcg twice daily; aged 6-17 years: 180 mcg twice daily
Qvar RediHaler (beclomethasone dipropionate HFA)12 years or older: 40, 80, 160, or 320 mcg twice daily; aged 4-11 years: 40 or 80 mcg twice daily

Frequently Asked Questions (FAQ) About Arunity

What is the recommended dosage for Arnuity?

The recommended dosage of Arnuity varies based on factors such as age, severity of asthma, and previous treatment history. It is typically administered once daily, and your healthcare provider determines the specific strength and dosage.

Are there any specific storage requirements for the medication?

Arnuity should be stored in a dry place at room temperature, away from direct sunlight and moisture. The inhaler device should be kept closed when not in use.

Can Arnuity be used in combination with other asthma medications?

Arnuity can be used alone or in combination with other asthma medications, as determined by your healthcare provider.

How long does it typically take Arnuity to show noticeable symptom improvement?

Individual responses to Arnuity may vary. Some patients may experience improvement in asthma symptoms within a few days, while others may take longer.

Are there any lifestyle changes or precautions patients should take while using Arnuity?

Patients using Arnuity should be cautious about potential interactions with other medications and inform their healthcare provider of all medicines, including over-the-counter and herbal supplements.

What should I do if I miss a dose of Arnuity?

If a dose of Arnuity is missed, the patient should take the missed dose as soon as remembered unless it is almost time for the next scheduled dose. The missed dose should be skipped, and the regular dosing schedule should be resumed.

Are there any common side effects associated with Arnuity?

Common side effects of Arnuity may include nasopharyngitis (nose and throat inflammation) and headaches. Please report any persistent or severe side effects to your healthcare provider.

How often should follow-up appointments be scheduled while using Arnuity?

Regular follow-up appointments with the healthcare provider are crucial for monitoring asthma control, assessing the need for dosage adjustments, and addressing any concerns or side effects.

Is there a risk of developing oral thrush with Arnuity?

While the risk of developing oral thrush (candidiasis) with Arnuity is relatively low, it is recommended to rinse the mouth with water after each use to minimize this risk.

Can Arnuity be used to relieve acute asthma symptoms?

No, Arnuity is not intended to relieve acute asthma symptoms or acute bronchospasm. It is specifically designed for maintenance treatment to prevent asthma exacerbations.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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