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Aczone (Dapsone)
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Aczone (Dapsone) gel is a prescription medication that treats acne in children and adults.
The medication is classified as an antimicrobial medicine. It contains an active ingredient called dapsone, a sulfone antibiotic, which reduces the amount of Propionibacteria acnes (the bacteria that cause acne breakouts).
The mechanism of its action is unknown, but it is documented to be similar to that of Clindamycin or Erythromycin.
Aczone may be used alone or along with other topical or oral acne medications. It helps in clearing acne faster and gives better results. You can consult with your doctor or dermatologist if it is the best treatment option for you.
Precautions and Warnings with Aczone
There are significant risks and warnings associated with Aczone. You should inform your doctor if you have a rash when using the medication as the skin rashes can be severe or fatal.
Pregnant women should not use Aczone unless their healthcare provider approves it. The same goes for breastfeeding mothers, as the medicine may pass into the baby through breast milk. This could affect the baby’s health.
It is unknown whether the medicine is safe for use for children under 12 years of age.
You should follow the directions for use on the package or consult with your healthcare provider before starting Aczone.
Your healthcare provider may not prescribe you Aczone gel if you have or have had a history of the following conditions:
- Allergy to dapsone
- Severe skin allergies
- Methemoglobinemia (oxygen level in the body dropping dangerously low)
- Glucose 6-phosphate dehydrogenase (enzyme in the cytoplasm of all cells in the body which prevents cellular damage from reactive oxygen species) deficiency
- Pancreatitis
- Thoughts of self-harm/suicide
Aczone Side Effects
It is important to be aware of the side effects that may occur when using Aczone gel. These reactions can be more pronounced which affects the physical condition of the patient.
If you are experiencing common side effects, it should be brought to your doctor’s attention. However, stop the medication and seek immediate medical assistance if you show signs of serious side effects.
Everybody reacts differently to the medicines and the above-listed side effects may not experienced by everyone. You can discuss the risks and benefits of Aczone with your doctor at the time of prescription.
At least 1% of people taking Aczone are reported to have shown side effects of the medicine. Many of these symptoms and side effects can be managed, while some may go away when consumed during the treatment.
You should monitor the patient’s condition to address the adverse effects caused by the medicine, as it is paramount for effective treatment.
Common Side Effects
- Redness in the targeted area
- Oily skin
- Dry or peeling skin
Serious Side Effects
- Swelling on the face or tongue
- Fever
- nausea and vomiting
- Severe skin reaction
- Severe sore throat
- Spreading purple or red skin rash
- Skin pain
- Blistering and peeling
- sore throat
- Burning sensation in eyes
- Pancreas problems
- Red blood cell disorder
- Severe pain in your upper stomach spreading to the back
- Irregular heartbeat
- Yellowed skin
- Dark colored urine
- Confusion or weakness
- Unusual thoughts or behavior
Drug Interactions with Aczone
Aczone gel has been reported to have less systemic effects than oral medications but it can still interact with other drugs. The interaction can increase blood levels or put the patient at risk of methemoglobinemia and hemolytic anaemia, especially in those patients with G6PD deficiency.
It is important to discuss your concerns about drug interactions for safe, effective treatment with your doctor, as they have the expertise in this regard. They can prepare your treatment plan by taking your underlying medical conditions and other medications into consideration.
It mitigates risks and side effects by adjusting dosages and considering alternative treatments that pose fewer risks. It helps doctors and patients make informed decisions about their health while prioritizing their well-being.
The following medicines are documented to interact with Aczone when taken together.
- Acetaminophen
- Anti-malarial medications (e.g. Hydroxychloroquine, Mefloquine, Primaquine)
- Benzocaine
- Benzoyl peroxide
- Nitrates (e.g., isosorbide dinitrate, isosorbide mononitrate, nitroglycerin)
- Xylocaine
- Metoclopramide
- Phenytoin
- Pramoxine (found in Proctofoam)
- Prilocaine
- Pyrimethamine
- Quinine
- Rifampin
- Tetracaine
- Trimethoprim
- Zopiclone
Strengths and Dosages of Aczone
Aczone gel is available in two strengths
- 5% (30g, 60g, 90g)
- 5% (30g, 60g, 90g)
| Strength | Active Ingredient | Inactive Ingredient |
| 5% | Dapsone | carbomer 980, diethylene glycol monoethyl ether (DGME), methylparaben, sodium hydroxide, and purified water |
| 7.5% | Dapsone | diethylene glycol monoethyl ether, methylparaben, acrylamide/sodium acryloyl dimethyl taurate copolymer, isohexadecane, polysorbate 80, and purified water |
You should wash your hands and the affected area before applying the medication.
You should pat dry the affected area before with a clean towel. Take a pea-sized amount of the medicine to apply each time. You may be prescribed to use benzoyl peroxide at the same time as Aczone, which may cause temporary changes in the color of your skin or facial hair.
Aczone gel should be used as directed by your doctor. You should follow all the directions on the prescription label.
The medicine should not be taken orally and is for use only on the skin. If this medicine comes in contact with your eyes, mouth, or vagina, then rinse it with water.
Cost of Aczone in America
Aczone gel can set you back between $733.35 and $780.88 without insurance.
There are certain insurance plans that cover a portion of the cost which reduces out-of-pocket expenses for patients. However, the coverage depends on the plan and whether the medicine is included in it.
The price may vary depending on:
- Pharmacy from where it was brought
- Insurance coverage
- Treatment plan
Why is Aczone so expensive?
Aczone is an expensive medicine because it is a brand-name drug, which typically costs more due to the extensive research and production costs that go into it. However, there are generic versions of the medicine that are available at lower prices.
Aczone Alternatives
It is important to understand the needs of the patients when selecting an Aczone’s alternative such as their condition and skin type. You should consult to make sure with your healthcare provider that the chosen treatment is a safe and effective option instead of self-medicating.
There are several effective alternatives to Aczone (dapsone) gel are available for treating acne with advantages and disadvantages. They promote cellular differentiation and decrease the formation of new comedones while alleviating inflammation.
A doctor may substitute Aczone with these variants:
- Spironolactone
- Doxycycline
- Isotretinoin
- Tretinoin
- Aldactone
- Clindamycin topical
- Accutane
- Minocycline
FAQs of Aczone
What is Aczone?
Aczone gel is a topical medication that treats acne in patients over the age of 12 years.
How does Aczone work?
Aczone contains an active drug called dapson which reduces inflammation and bacterial growth in the skin. It treats the redness and swelling caused by acne lesions whereas the antimicrobial properties fight the bacteria that exacerbate acne.
How long does Aczone take to work?
Aczone is documented to be effective within 12 weeks of consistent use.
How to apply Aczone?
Aczone should be applied once daily to clean dry skin. A thin layer of gel should be spread evenly on affected areas while avoiding contact with the eyes, mouth, and mucous membranes.
What type of acne does Aczone treat?
Aczone treats both inflammatory and non-inflammatory acne lesions. It relieves symptoms associated with acne vulgaris, such as redness and swelling.
Can you use Aczone and Retin-A together?
Yes, Aczone and Retin-A (tretinoin) can be used together, but with caution. However, the simultaneous application may increase the risk of skin irritation. Therefore, it is recommended to use them at different times of the day.
Is there a generic for Aczone?
Yes, a generic version of Aczone (dapsone) gel is available. The generic version provides the same active ingredient and is a low-cost option.
Our Guarantee For Buying Aczone From A Canadian Pharmacy Partner
At MyRx Outlet, we are committed to delivering safe, high-quality medications that you can trust. We adhere to strict regulations in every country we operate in, ensuring that your order is handled by a licensed Canadian pharmacy or a trusted partner overseas. Each medication has been legally approved by Health Canada or other respected authorities. To purchase Aczone at a discounted rate, call 1-888-551-2467.
IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.
