Soolantra is a prescription cream that contains the active ingredient ivermectin. It is specifically formulated to treat inflammatory lesions caused by rosacea. Rosacea is a chronic skin condition that primarily affects the face, resulting in redness, visible blood vessels, and acne-like bumps. Soolantra is applied topically to the affected areas and works by reducing the inflammation associated with rosacea.

Soolantra works by targeting the Demodex mites that are believed to play a role in the development of rosacea. Demodex mites are microscopic parasites that naturally live on the skin, including the facial area. However, in individuals with rosacea, it is thought that these mites may contribute to the inflammation and immune response that leads to the characteristic symptoms of the condition.

Soolantra’s active ingredient, ivermectin, has both anti-inflammatory and anti-parasitic properties. When applied to the affected areas, it reduces the number of Demodex mites and helps alleviate the associated inflammation. By targeting these mites, Soolantra helps improve the overall appearance of the skin, reducing redness, swelling, and the presence of acne-like bumps.

Soolantra is primarily used by individuals diagnosed with rosacea. Rosacea affects millions of people worldwide and can cause significant discomfort and embarrassment due to its visible symptoms. This condition commonly affects adults between the ages of 30 and 50, although it can also occur in younger individuals and occasionally in children.

If you have been diagnosed with rosacea by a healthcare professional, they may recommend Soolantra as part of your treatment plan. It is important to follow your doctor’s instructions carefully and use the medication as prescribed to achieve the best results.


Rosacea is a chronic inflammatory skin condition that primarily affects the face. It is characterized by persistent redness, visible blood vessels (telangiectasia), and sometimes small, red, pus-filled bumps (papules) or pustules. Rosacea often develops gradually, starting with occasional flushing or blushing that may be mistaken for a temporary condition. However, over time, the symptoms become more persistent and can significantly impact an individual’s quality of life.

Rosacea is a common skin condition that affects millions of individuals worldwide. It typically manifests as persistent facial redness, visible blood vessels, and in some cases, acne-like bumps. While the exact cause is uncertain, various factors like genetics, abnormal blood vessels, and environmental triggers are thought to play a role. Understanding the symptoms, triggers, and available treatment options is crucial for managing rosacea effectively.

Rosacea and acne share some similarities, but they are distinct conditions with different causes and treatment approaches. Differentiating between the two is crucial for receiving appropriate treatment. While both conditions can present with bumps on the face, rosacea is typically characterized by persistent redness and visible blood vessels, while acne is associated with blackheads, whiteheads, and more severe inflammatory lesions.

Warnings and Precautions

While Soolantra can be an effective treatment, it’s essential to be aware of the warnings and precautions associated with its use.

  • Allergy and Sensitivity: Individuals who are allergic to ivermectin or any other ingredients in Soolantra should avoid using this medication. If you have a history of allergic reactions to medications, it is crucial to inform your healthcare provider before initiating treatment.
  • Medical Conditions and Medications: Inform your healthcare provider about any existing medical conditions or medications you are taking. Certain conditions or medications may interact with Soolantra or increase the risk of adverse effects. It is particularly important to mention if you have a weakened immune system or if you are taking immunosuppressive medications.
  • Application on Broken or Damaged Skin: Soolantra is designed for topical use on intact skin. It should not be applied to broken or damaged skin, as it may lead to increased absorption and potential systemic side effects. If you have open wounds, cuts, or any other skin conditions, consult your healthcare provider before using Soolantra.
  • Eye Contact: Avoid direct contact with your eyes when applying Soolantra. In case of accidental contact, rinse your eyes thoroughly with water. If eye irritation persists, seek medical attention.
  • Sun Exposure: While using Soolantra, it is important to protect your skin from excessive sun exposure. Wear protective clothing and use sunscreen with a high sun protection factor (SPF) to prevent sunburn and further skin damage.

Side Effects

While Soolantra is generally considered safe and effective, it is important to be aware of potential side effects that may occur during its use.

Common Side Effects

  • Skin irritation and redness at the application site
  • Burning or stinging sensation
  • Dry skin
  • Itching or tingling

Rare Side Effects

  • Allergic reactions, such as rash, hives, or itching
  • Swelling of the face, lips, tongue, or throat
  • Eye irritation or redness
  • Worsening of rosacea symptoms

Severe Side Effects

  • Severe skin irritation, including blistering, crusting, or oozing
  • Severe skin rash or peeling
  • Swelling of the face, lips, tongue, or throat with difficulty breathing
  • Vision changes or eye pain


While Soolantra is effective in managing the symptoms of rosacea, it’s essential to understand the potential interactions it may have with other drugs, herbs, and food.

Drug Interactions

  • Antibiotics: Soolantra is generally safe to use alongside antibiotics prescribed for other conditions. However, it’s crucial to inform your healthcare provider about all the medications you are taking to ensure there are no potential interactions or adverse effects.
  • Oral Corticosteroids: While there is no known interaction between Soolantra and oral corticosteroids, it’s advisable to consult your doctor if you are using both medications simultaneously. They can provide personalized guidance based on your specific health condition and medication regimen.
  • Antifungal Medications: Using antifungal medications concomitantly with Soolantra may not pose any significant risks or interactions. However, it’s always recommended to consult your healthcare provider before combining medications to ensure optimal safety and efficacy.
  • Blood Thinners: There are no known interactions between Soolantra and blood thinners, such as warfarin or aspirin. Nevertheless, it’s essential to inform your healthcare provider about all the medications you are taking to prevent any potential complications.
  • Immunosuppressants: The concurrent use of Soolantra and immunosuppressant medications should be discussed with your healthcare provider. They will evaluate the potential risks and benefits, taking into consideration your specific medical condition and treatment requirements.

Herbal Interactions

  • St. John’s Wort: St. John’s Wort is an herbal supplement known for its mood-enhancing properties. However, combining it with Soolantra may reduce the efficacy of the medication. It is recommended to avoid using St. John’s Wort while using Soolantra.
  • Echinacea: Echinacea is commonly used to support the immune system. Although no significant interactions have been reported, it’s advisable to consult your healthcare provider before using Echinacea alongside Soolantra.
  • Ginkgo Biloba: Ginkgo Biloba is an herbal supplement often used to improve cognitive function. While there are no known interactions between Ginkgo Biloba and Soolantra, it’s recommended to consult your healthcare provider to ensure their safe and effective concurrent use.
  • Garlic: Garlic is a popular ingredient known for its various health benefits. However, there are no established interactions between garlic and Soolantra. It’s always prudent to discuss the use of garlic supplements or excessive garlic consumption with your healthcare provider.
  • Ginseng: Ginseng is an herbal supplement used for its energizing properties. Although no direct interactions have been reported between Ginseng and Soolantra, it’s advisable to consult your healthcare provider before combining them to ensure optimal safety and efficacy.

Food Interactions

  • Grapefruit Juice: Grapefruit juice may inhibit the metabolism of certain medications, potentially increasing their concentration in the body. However, there is no known interaction between Soolantra and grapefruit juice. It’s always best to consult your healthcare provider regarding specific dietary restrictions while using Soolantra.
  • Alcohol: While there are no direct interactions between Soolantra and alcohol, excessive alcohol consumption can exacerbate the symptoms of rosacea. It’s recommended to moderate alcohol intake and consult your healthcare provider for personalized guidance.
  • Caffeine: Caffeine consumption does not directly interact with Soolantra. However, excessive caffeine intake may trigger flushing and worsen the symptoms of rosacea. Moderation is key, and individual tolerance should be considered.
  • Spicy Foods: Spicy foods do not have any known direct interactions with Soolantra. However, they may induce flushing and exacerbate rosacea symptoms in some individuals. It’s advisable to identify and avoid specific triggers based on personal experiences.
  • Dairy Products: There are no known interactions between Soolantra and dairy products. However, some individuals with rosacea may find that dairy exacerbates their symptoms. If you suspect a connection between dairy consumption and your rosacea flare-ups, it’s recommended to consult your healthcare provider for personalized advice.

How to Use

Applying Soolantra correctly is essential for obtaining the best results.

  1. Squeeze a pea-sized amount: Start by squeezing a pea-sized amount of Soolantra onto your fingertip. Remember, a little goes a long way.
  2. Apply to affected areas: Gently massage the cream onto the affected areas of your face, including the cheeks, nose, chin, and forehead. Avoid the eye area.
  3. Spread evenly: Use your fingertips to spread the cream evenly, ensuring all affected areas are covered. Don’t apply too much pressure, as it may irritate your skin.
  4. Wash your hands: After applying Soolantra, wash your hands thoroughly to remove any residual cream.
  5. Follow your doctor’s instructions: Soolantra is a prescription medication, so it’s crucial to follow your doctor’s instructions regarding application frequency and duration.


To achieve optimal results and manage rosacea symptoms, it is essential to follow the appropriate dosing regimen.

Initial Dosing

When starting Soolantra, it is crucial to follow the recommended initial treatment dosing to achieve the best results. The standard dosage for Soolantra is a pea-sized amount applied once daily to the affected areas of the face. Before application, ensure that your face is clean and dry. Gently massage the cream into the skin until it is evenly distributed. Avoid contact with your eyes, lips, and mouth.

It is important to note that the duration of the initial treatment phase may vary depending on the severity of your rosacea symptoms. Your healthcare provider will provide specific instructions on how long to continue the initial treatment phase before transitioning to the maintenance regimen.


After completing the initial treatment phase, it is necessary to follow a maintenance regimen to manage your rosacea effectively. The maintenance dosing of Soolantra is the same as the initial treatment dose, which is a pea-sized amount applied once daily to the affected areas of the face. Continue to clean and dry your face before applying the cream and ensure even distribution by gently massaging it into the skin.

Adhering to the maintenance regimen is vital to maintain the benefits of Soolantra and prevent the recurrence of rosacea symptoms. Consistency is key in managing this chronic skin condition effectively.

Missed Dose

Occasionally, you may forget to apply Soolantra at the scheduled time. Consistency in applying Soolantra is essential for the medication to work effectively. However, if you occasionally miss a dose, it should not significantly impact your overall treatment. If you miss a dose, there are specific guidelines to follow:

  • If you remember within a few hours of the missed dose, apply the cream as soon as possible. Resume your regular dosing schedule the following day.
  • If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing regimen.
  • Do not apply extra cream to make up for the missed dose, as this may increase the risk of side effects.


Using Soolantra as directed is generally safe, but it is essential to be aware of the potential symptoms of an overdose. While an overdose is unlikely with topical use, it is still important to exercise caution.

If you accidentally apply too much Soolantra or experience any adverse reactions, such as severe skin irritation, redness, or itching, contact your healthcare provider immediately or seek medical attention. They will provide guidance on the appropriate steps to manage the situation and alleviate any discomfort.


Proper storage of Soolantra is crucial to maintain its effectiveness and ensure that it remains safe to use.

  • Ideal Temperature for Storing Soolantra: To maintain the efficacy of Soolantra, it is essential to store it at room temperature. The ideal temperature range for storing Soolantra is between 68°F (20°C) and 77°F (25°C). Avoid exposing the cream to extreme temperatures, as this can degrade its active ingredients.
  • Avoid Exposure to Light and Moisture: Soolantra should be protected from direct sunlight and excessive moisture. Exposure to light and moisture can degrade the cream and reduce its effectiveness. To prevent this, store Soolantra in its original packaging, tightly closed, in a cool and dry place away from windows, sinks, showers, or any other source of moisture.
  • Store Soolantra Away from Children and Pets: It is crucial to keep Soolantra out of reach of children and pets. The cream is intended for topical use only and should not be ingested. Store it in a secure location, such as a high shelf or a locked cabinet, to prevent accidental ingestion or misuse.
  • Proper Container for Soolantra: Soolantra should always be stored in its original container. The packaging is designed to protect the cream from external factors and maintain its stability. Do not transfer the cream to another container unless specifically instructed by your healthcare provider or pharmacist.


When it comes to medications like Soolantra, it’s essential to dispose of them properly to protect ourselves, others, and the environment.

  1. Check the expiration date: Before disposing of any medication, including Soolantra, check the expiration date. Expired medications should not be used or disposed of inappropriately.
  2. Keep the original packaging: It is important to keep Soolantra in its original packaging until it is time to dispose of it. The packaging contains essential information, such as the drug’s name and dosage, which can be useful for proper identification.
  3. Do not remove labels: Avoid removing or tampering with the labels on the Soolantra packaging. The labels provide crucial information for identification and ensure safe handling during the disposal process.
  4. Consult your pharmacist: If you are unsure about the proper disposal method for Soolantra or have any specific concerns, consult your pharmacist. They can provide you with detailed guidance based on local regulations and best practices.
  5. Mix with undesirable substance: To discourage accidental consumption, mix the Soolantra medication with an undesirable substance such as coffee grounds or cat litter. This helps prevent misuse and makes the medication less appealing to children or pets.
  6. Seal the container: Place the mixture of Soolantra and the undesirable substance in a sealable bag or container. Make sure it is securely closed to prevent leakage or spills.
  7. Secure disposal: Contact your local waste management facility or check for any drug take-back programs in your area. These programs ensure the safe and proper disposal of medications like Soolantra. Follow their guidelines for drop-off or collection.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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