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Farxiga (dapagliflozin) stands as one of the top options for managing Type 2 diabetes, with the added proven benefits for heart disease and chronic kidney disease patients. As with any medication, patients are encouraged to be aware of the common side effects. Remaining on top of symptoms and side effects helps doctors prescribe medication that works.
This article aims to be a guide on the side effects of Farxiga, allowing patients to remain informed on their physical health.
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Farxiga is an SGLT2 inhibitor-style medication, that stands for sodium-glucose co-transporter 2. Farxiga works by blocking (inhibiting) the reabsorption of some sugar and sodium in the kidneys. This is helpful for people with chronic kidney disease, heart failure, and type 2 diabetes.
Not just diabetes, it can also lower the risk of heart attacks and strokes in its patients. That means it can be prescribed for conditions such as type 2 diabetes, kidney-related illnesses, and heart conditions. Getting the most out of Farxiga is simple, just follow the doctor’s game plan for dosage and timing. Being armed with the knowledge of side effects can help patients work in tandem with their medical team.
Below is a breakdown of the most commonly reported side effects reported from Farxiga:
Farxiga removes glucose through a patient’s urine, that increased glucose is perfect for fungi and bacteria. Increased fungi can cause genital yeast infections while increased bacteria can cause urinary tract infections. Both men and women are at an increased risk for either of these two side effects.
Keeping clean may require a little extra attention while on Farxiga. Let a doctor know if any symptoms of either start to occur:
Prompt treatment can save patients from more dangerous side effects like Fournier’s gangrene.
Since Farxiga uses the kidneys and urination to remove glucose and sodium, increased urination is common. While not dangerous, this can be an annoying symptom for many.
Taking the medication in the morning can help patients avoid nighttime bathroom emergencies.
One of the top three most common side effects along with the two mentioned already. These side effects should go away as a patient becomes used to the medication.
Frequent urination also causes the need for increased fluid intake. Failure to compensate can lead to mild or extreme dehydration. Dehydration will put extra strain on a patient’s kidneys, so it is important to pay attention to one’s intake to avoid increased damage for those with chronic kidney disease.
A doctor will order regular blood draws to make sure kidney function remains normal while on Farxiga. Besides that, they can answer what proper hydration will look like and what amount a patient should be aiming for each day.
Unfortunately, Farxiga has the possibility of making a patient feel sick to their stomach. This should ease up if the medication is taken with food.
If the nausea simply won’t go away or gets worse, a doctor may need to consider different medications.
Weight loss was reported in some during clinical trials. This is a side effect and should not be the main function of the medication. If a patient and their care team are comfortable with the weight loss then they can remain on Farxiga.
While some side effects are mild inconveniences, others can put a patient at serious risk. If taking Farxiga, keep an eye out for any of the side effects listed below:
Diabetic Ketoacidosis can occur when the body doesn’t have enough insulin which means too much blood sugar. The body responds by breaking down fat and creating ketones (the keto- in ketoacidosis). Diabetic Ketoacidosis is life-threatening, make sure to go to the hospital if any of the following symptoms occur:
Pyelonephritis and urosepsis are two kidney infections that can occur with Farxiga. Both are serious conditions that require hospital treatment. Pyelonephritis is an infection that originates in the kidneys while urosepsis begins as a UTI which spreads to the kidneys.
Symptoms for either of these can include:
Especially when paired with other diabetes medication, Farxiga has the possibility of causing severe low blood sugar, aka hypoglycemia. If this side effect occurs, it may be fixed with just a lower dosage of diabetes medication. However, remaining aware of the symptoms can save a patient’s life as hypoglycemia can turn deadly.
Many patients might not know they are allergic until they have their first allergic reaction. Allergic reactions include symptoms like swelling of the face, tongue, or throat and trouble breathing. You may also get a mild case which involves a rash or blister that spreads out across any area of the body.
If a patient is already aware of a medication they are allergic to, double-check ingredients and then check again by asking the doctor if Farxiga is safe.
Mentioned briefly above, this side effect can occur when a genital yeast infection is left untreated. This is a severe form of the infection and needs hospital treatment. Symptoms include:
The side effects listed above are not common but are serious. Medication should be stopped and a patient should see a medical professional as soon as possible if they think they have any of the side effects listed.
Some medications that interact negatively with Farxiga include lithium and sulfonylureas (glimepiride, glipizide, glyburide).
Let a doctor know of any of these increased risk factors when considering Farxiga. Some can be mitigated while others would require a different medication to be prescribed.
A patient’s age and overall health are also considered when using Farxiga. It is only for adults and children ages 10 and up.
As with any medication, there are steps a patient can take to remain ahead of any side effects. Being aware of which side effects are common and which could be severe is part one of that. Avoiding alcohol can also help prevent side effects along with staying hydrated.
There are a few things patients can keep an eye on themselves to avoid serious side effects. Cleanliness for both males and females can help avoid UTIs and genital yeast. Monitoring blood sugar for odd spikes or falls can also alert you to any side effects before they evolve into something worse. Let a doctor know of any and every concern! Teamwork makes the dream work when it comes to a patient’s health.
With new medication, the answer is it is always better to be safe than sorry. Contact your doctor if any of the symptoms above occur or if previously noted side effects are getting worse. If any side effects in the severe category occur, go to the hospital and then notify your primary care.
Farxiga isn’t the only medication for type 2 diabetes or even the only SGLT2 inhibitor. Some other types of SGLT2 inhibitors include Jardiance and Invokana.
Other diabetes medications work in different ways and may be better if Farxiga is causing negative side effects. GLP-1 receptor agonists are another type and include Byetta, Trulicity, Rybelsus, and Ozempic.
Lifestyle changes are mentioned often and play a huge role in many conditions like diabetes. Exercise, weight loss, and special diets meant for people with diabetes have the power to limit what medications a patient needs. They even have the power to eliminate the need for medication at all.
Farxiga is used to treat type 2 diabetes, chronic kidney disease, and heart disease. It isn’t the only one out there however and serious side effects may mean a patient needs to switch. That is why staying knowledgeable of side effects makes a world of difference in a patient’s medical treatment.
Work hand in hand with your healthcare professional by letting them know if any side effects. Sometimes a problem can be solved with a change in dosage, other times a completely new medication is needed. Whatever the case, Farxiga is here to help manage type 2 diabetes and get patients on track for a healthier, happier life.
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Farxiga can be taken at any time as long as you aren’t having any side effects. Frequent urination at night can be solved by simply switching to taking the medication in the mornings.
Caffeine and Farxiga both can increase urination which can lead to dehydration. While there aren’t any negative interactions between the two, caffeine consumption should be limited.
Farxiga should cause unusual or increased tiredness. The conditions Farxiga treats may cause it though. Let your doctor know if any increased tiredness to make sure there isn’t something more serious going on.
You should not stop Farxiga suddenly. Stopping cold turkey can worsen the very conditions this drug is meant to treat.
Written & Reviewed By
The MyRx Team
The MyRx Outlet team is a dedicated group of healthcare professionals and pharmacists dedicated to delivering up-to-date and accurate information on medications and key healthcare topics. With years of experience in the healthcare field, our team is passionate about supporting individuals in reaching their health and wellness goals through our articles.
The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.
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