
What Is Compounded Tirzepatide?
Learn what compounded tirzepatide is, how it differs from Mounjaro and Zepbound, and what to know about its safety, cost, and FDA regulations.
🎄Holiday Notice: Shipping for temperature-sensitive medications (Ozempic, Mounjaro, etc.) is paused. Service resumes Monday, Dec 29.
Generic Semaglutide Now Available!
We Ship To The U.S. Only
Call Toll Free:
Table of Contents
Toggle10% OFF
On Your First Order
Copy Code
MYRX10
10% OFF
On Your First Order
Copy Code
MYRX10
Ozempic and Mounjaro are two commonly used drugs for promoting weight loss and treating type 2 diabetes. While both drugs share a lot of similarities, they also have some key differences. When looking at Ozempic vs Mounjaro, some key factors to consider are what the drugs are, what they are used for, their active components, their mechanism of action, and their effectiveness. Comparing the two drugs can help you identify which medication is better suited for you. In this blog, we will explore these different factors, as well as Ozempic vs Mounjaro side effects, Ozempic vs Mounjaro cost, and the difference between Mounjaro and Ozempic.
Mounjaro is a brand name for tirzepatide. It is an effective glucagon-like peptide-1 (GLP-1) receptor that is used to treat patients suffering from type 2 diabetes mellitus. This injectable medication is commonly associated with significant weight loss and is prescribed off-label for chronic weight management in some cases.
For patients using Mounjaro for type 2 diabetes, the medication offers many benefits, including enhanced metabolic health, better insulin sensitivity, lowered blood sugar levels, lowered risk of cardiovascular events, potential improved glucose control, reduced risk of diabetic complications, and reduced need for taking other diabetes drugs. For those taking the drug for weight management, they may experience reduced appetite, lowered body mass index (BMI), improved overall metabolic health, and potentially reduced risk of obesity-related comorbidities. Significant improvements may be noticeable in 12-16 weeks of starting treatment.
Mounjaro was approved by the U.S. Food and Drug Administration (FDA) in May 2022. The drug comes in the form of a once-weekly injection where it then works to reduce blood sugar and effectively promote weight reduction. Moujaro is typically taken by being injected into the body once per week. The medication can be injected straight into the stomach, thigh, or upper arm. The typical starting dose for Mounjaro is a weekly dose of 2.5 mg. This is usually then increased to a weekly dose of 5 mg after four weeks. Finally, patients may be prescribed a maximum dose of 15 mg per week.
Moujaro is a tirzepatide, which means it is a dual incretin agonist. After a meal, the digestive system produces hormones known as incretins. These hormones include GLP-1s and glucose-dependent insulinotropic polypeptides (GIPs). These incretins play a crucial role in stimulating the pancreas to release insulin and therefore help lower blood glucose levels.
They also inhibit the production of glucagon This is the hormone that prompts the liver to release stored glucose, thereby preventing an increase in blood glucose levels. By slowing down the emptying of the stomach, the incretins delay the release of glucose into the bloodstream and promote a feeling of fullness.
Ozempic is an FDA-approved medication that falls under the category of glucagon-like peptide-1 receptor agonist (GLP-1 RA) drugs. It contains the active ingredient semaglutide and imitates the functions of glucagon-like peptide-1 (GLP-1), a hormone naturally found in the body. Ozempic was originally used to treat type 2 diabetes, but approval of semaglutide was eventually extended for obesity treatment as well.
The drug comes pen with prefilled medication that is injected into the body once per week. It can be injected into the abdomen, front of the thighs, or upper arms. The typical dosing recommendations for patients include an initial weekly dose of 0.25 mg. This is usually then increased to a maintenance dose of 0.5 mg after four weeks. Some patients are prescribed a maximum weekly dose of 1 mg.
Once injected into the body, Ozempic mimics the natural GLP-1 hormone in the body. The hormone is released after food consumption and stimulates insulin production from the pancreas. This slows the rate of food emptying from the stomach and creates a sense of fullness.
When used for type 2 diabetes, Ozempic helps to regulate blood sugar, lessens the risk of hyperglycemia, reduces the risk of cardiovascular diseases, and promotes weight loss. It is also a convenient option for those who prefer to use fewer medications. When used for weight loss, Ozempic can improve cardiovascular health, insulin sensitivity, and glycemic control. It can also reduce cravings and desire for unhealthy foods. Best weight loss results can be experienced when the rug is combined with a healthier lifestyle.
Although both drugs can be used to treat type 2 diabetes and promote weight loss, there are some key differences between Moujaro and Ozempic. First, the two drugs contain different active components. Ozempic contains the active ingredient semaglutide which is what creates the feeling of fullness that leads to appetite suppression. Mounjaro contains the active ingredient tirzepatide. This ingredient works in the same way as the incretin hormones GLP-1 and GIP. By doing so, Mounjaro stimulates the pancreas to release insulin and helps lower blood glucose levels.
Moujaro and Ozempic also have slightly different mechanisms of action. Ozempic is a GLP-1 receptor agonist that mimics the natural GLP-1 hormone in the body and binds to the GLP-1 receptor to create its effect. Tirzepatide is dual-acting for mimicking both GIP and GLP-1 receptor agonists. It binds to both GIP and GLP-1 receptors instead of just GLP-1 to increase the action of the drug. Both medications stimulate insulin release from the pancreas to help lower blood sugar levels. They also decrease the amount of sugar produced by the liver by suppressing glucagon secretion and slowing gastric emptying through the stomach, which creates a sense of fullness for a longer period of time. This leads to decreased appetite and weight loss.
There is also a slight price difference between Moujaro and Ozempic. Without insurance or any other coupons or discounts, the average cost of 5 mg/0.5 mL of Mounjaro subcutaneous injection is $1135 for a one-month supply. The average cost for Ozempic without insurance or any other coupons or discounts is an average of $1029 for a one-month supply of 2 mg/3 mL subcutaneous injections. These drugs can be bought using a prescription from a healthcare provider or from online prescription referral services, such as MyRX Outlet.
Both Moujaro and Ozempic have been used for weight loss. This primarily occurs through a reduction of fat mass. However, studies show they do not have the same effectiveness. For example, a study done by Truveta Research found in one study comparing the two drugs that patients on Mounjaro lost 5.9% of their weight within three months while those on Ozempic lost 3.6% of their weight. At six months, those who were taking Mounjaro lost 10.1% of their weight, and those who took Ozempic lost 5.9% of their weight. Finally, after one year of taking the drugs, the group taking Mounjaro lost 15.2% of their weight, and those on Ozempic only lost 7.9% of their weight.
Another study analyzing the effectiveness for weight loss of tripeptide vs. semaglutide — the two active ingredients in Mounjaro and Ozempic — found that using tirzepatide resulted in a weight loss of 17.8% as opposed to 12.4% for semaglutide. While both drugs proved effective for quick weight loss, Mounjaro helped patients lose weight at a quicker rate.
Mounjaro and Ozempic may have many differences, but they also share many similarities. Both drugs are used to improve the effects of type 2 diabetes and for assistance with weight loss. They are also in the same drug class called “incretin mimetics.” This simply means that both drugs mimic the actions of the incretin hormone GLP-1. Neither Ozempic nor Mounjaro have a generic version available.
There are many possible side effects to both Mounjaro and Ozempic. The most common side effects of Ozempic include mild and temporary headaches, nausea following the administration of the medication, diarrhea due to changes in the digestive system, and reactions at the site of injection. Reactions may include redness, swelling, and itching. The most common side effects of Mounjaro affect 5% of patients. These effects include fatigue, nausea, vomiting, diarrhea, dizziness, headache, decreased appetite, abdominal discomfort, and reactions at the site of injection.
Both of these drugs also have a range of rare but severe side effects. For Ozempic, this includes pancreatitis, thyroid tumors, hypoglycemia, or kidney problems. Sometimes allergic reactions may occur. Symptoms of an allergic reaction include itching, problems breathing, facial inflammation, or swelling of the face, lips, tongue, or throat. The most severe possible side effects of Ozempic include retinopathy, cardiovascular events like heart attack or stroke, acute kidney injury, or severe allergic reactions like anaphylaxis, with symptoms including difficulty breathing, rapid heartbeat, severe swelling, and loss of consciousness. Patients may also experience an increased risk of pancreatic cancer with symptoms including persistent abdominal pain, unexplained weight loss, and yellowing eyes or skin.
The most severe side effects of Moujaro include vision changes, unusual lumps or swelling in the neck, or severe allergic reactions such as swelling and difficulty breathing. In some rare cases, patients have also experienced pancreatitis, hypoglycemia, acute kidney injury, and gallbladder problems from taking Moujaro. All of these side effects are serious and require immediate medical attention. Both those taking Ozempic and Moujaro should avoid alcohol, caffeine, grapefruit or grapefruit juice, high-fat meals, and foods that are high in sugars.
Both Mounjaro and Ozempic have a long list of possible drug interactions as well. Those taking Mounjaro should avoid oral contraceptives, laxatives like bisacodyl, anticoagulants like warfarin, antibiotics like erythromycin, antidiabetic drugs metformin, corticosteroids like prednisone, antacids like aluminum hydroxide, and thyroid supplements like levothyroxine. Mounjaro may also have some harmful interactions with some herbal supplements as well. Some of these ingredients include garlic, yarrow, valerian, ginseng, turmeric, cinnamon, aloe vera, echinacea, dong quai, astragalus, milk thistle, goldenseal, devil’s claw, licorice root, saw palmetto, and black cohosh.
Those taking Ozempic may experience drug interactions with insulin, corticosteroids, anticoagulant medications, sulfonylureas such as Glipizide or Glimepiride, and antibiotics, such as Clarithromycin or Erythromycin. Ozempic may also interact with drugs that delay gastric emptying, such as opioids or anticholinergics. Ingredients that may cause herbal interactions with Ozempic include garlic, ginseng, cinnamon, milk thistle, ginkgo biloba, and St. John’s Wort. Before taking either medication, patients should let their healthcare provider know if they are taking any of these drugs or ingredients as they may cause harmful interactions.
Both of these drugs have also not been extensively studied yet to note the impact they may have during pregnancy. The side effects for the infant and mother are still unknown. It is best to avoid both drugs if you are pregnant or plan to become pregnant The effects of the medications in breast milk are also not yet known. Those taking either Mounjaro or Ozempic should not breastfeed while on the drug as it may cause unexpected complications.
There are a lot of factors to consider for diabetics, caregivers, healthcare providers, and those who are exploring different medication options who are looking at Moujaro vs Ozempic to address their health concerns. Mounjaro is well suited for improving metabolic health and insulin sensitivity, and lowering blood sugar levels and risk of cardiovascular events. It is also good for the potential improvement of glucose control, mitigating the risk of diabetic complications, and reducing the need for taking other drugs to help with diabetes. Ozempic is good for reducing the risk of hyperglycemia and cardiovascular diseases, as well as reglauting blood sugar and also reducing reliance on other medications. Both drugs can also be used for weight loss. Online resources are available for more information..
Both Ozempic and Mounjaro have drawn up countless discussions within weight loss communities. Knowing their similarities and differences can help inform you of the two treatments. However, it would be up to your healthcare practitioner to prescribe you the medication they believe would be the right fit.
If you are a current customer and have questions about Ozempic or Mounjaro, feel free to contact us and we will connect you with one of our licensed pharmacists to discuss further.
Written & Reviewed By
The MyRx Team
The MyRx Outlet team is a dedicated group of healthcare professionals and pharmacists dedicated to delivering up-to-date and accurate information on medications and key healthcare topics. With years of experience in the healthcare field, our team is passionate about supporting individuals in reaching their health and wellness goals through our articles.
The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.
Related Articles

Learn what compounded tirzepatide is, how it differs from Mounjaro and Zepbound, and what to know about its safety, cost, and FDA regulations.

Learn what compounded tirzepatide is, how it differs from Mounjaro and Zepbound, and what to know about its safety, cost, and FDA regulations.

What happens when you stop taking Mounjaro? Learn about weight regain, blood sugar changes, and how to manage side effects after discontinuing.
Share:
What Is A Generic?
×A generic drug is essentially a copycat version of a brand-name medication, offering the same safety, quality, and effectiveness, but often at a lower cost. When a brand-name drug's patent expires, other companies can produce the generic version. These generics contain the same active ingredients and work in the same way in the body as the original brand-name drug. However, they might differ in color, shape, or inactive ingredients. The appeal of generic drugs lies in their affordability; they provide a more cost-effective option for consumers without sacrificing the benefits of the original medication. This makes healthcare more accessible to a larger portion of the population, ensuring that more people can receive the treatment they need without the burden of high costs associated with brand-name drugs.