Omnaris is an intranasal corticosteroid that belongs to the class of medications known as anti-inflammatory agents. Its primary function is to alleviate the symptoms of various respiratory conditions by reducing inflammation and swelling in the nasal passages. The active ingredient in Omnaris is ciclesonide, which works locally to provide relief without causing significant systemic effects.

When Omnaris is administered as a nasal spray, ciclesonide binds to specific receptors in the nasal mucosa. This binding action inhibits the release of inflammatory substances, such as histamines and leukotrienes, which are responsible for causing nasal congestion, sneezing, and itching. By blocking these inflammatory mediators, Omnaris effectively reduces the swelling in the nasal passages, allowing for easier breathing and relief from allergy symptoms.

Omnaris is primarily used to manage allergic rhinitis, both seasonal and perennial, in adults and children aged six years and older. Allergic rhinitis, commonly known as hay fever, is characterized by symptoms like sneezing, nasal congestion, runny nose, and itchy or watery eyes. Omnaris helps alleviate these bothersome symptoms, improving the quality of life for those suffering from allergies.

Allergic Rhinitis

Allergic rhinitis is an allergic response to airborne substances, such as pollen, pet dander, dust mites, and mold spores. When an individual with allergic rhinitis is exposed to these allergens, their immune system releases histamines and other chemicals, leading to the typical symptoms associated with the condition.

Seasonal Allergic Rhinitis is a type of allergic rhinitis that occurs primarily during specific seasons when certain allergens are prevalent, such as pollen during the spring. Perennial Allergic Rhinitis persists throughout the year, unlike Seasonal Allergic Rhinitis, as it is triggered by perennial allergens like pet dander and dust mites.

Warnings and Precautions

While Omnaris can be highly effective, it’s crucial to be aware of its warnings and precautions to use it safely.

  • Allergic Reactions to Omnaris: While Omnaris is intended to alleviate allergic symptoms, some individuals may experience allergic reactions to the medication itself. If you notice any signs of an allergic reaction, such as skin rash, itching, swelling, or difficulty breathing, discontinue use immediately and seek medical attention.
  • Underlying Medical Conditions: Individuals with certain medical conditions may need to exercise caution while using Omnaris. Conditions like tuberculosis, untreated fungal, bacterial, or viral infections, or recent nasal surgery may require alternative treatment options. Always inform your doctor about your medical history before starting Omnaris.
  • Drug Interactions: It’s essential to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medicines, and herbal supplements. Certain medications may interact with Omnaris, leading to adverse effects or reduced efficacy.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Omnaris with your healthcare provider. The medication may pass into breast milk, potentially affecting the nursing infant.
  • Long-Term Use: Avoid using Omnaris for extended periods without medical supervision. Prolonged use of corticosteroid nasal sprays may lead to adverse effects like nasal mucosa thinning or increased risk of nasal infections.
  • Pediatric Use: While Omnaris is generally safe for children over 12 years, consult a pediatrician before administering the medication to younger children.

Side Effects

While Omnaris is effective for many individuals, it’s essential to be aware of the potential side effects it may cause.

Common Side Effects

  1. Nasal Irritation and Dryness: A frequently reported side effect of Omnaris is mild irritation or dryness in the nasal passages. This sensation is usually temporary and diminishes as your body adjusts to the medication.
  2. Headache: Some individuals may experience mild headaches during the initial days of using Omnaris. These headaches are generally short-lived and subside with continued use.
  3. Sneezing: Surprisingly, a small percentage of patients may experience increased sneezing when they start using Omnaris. This paradoxical reaction usually fades over time.
  4. Throat Irritation: In some cases, Omnaris may cause mild irritation or a slight sore throat. Gargling with warm saltwater can help alleviate this discomfort.
  5. Nosebleeds: Occasional nosebleeds have been reported with the use of Omnaris. If you experience frequent or severe nosebleeds, consult your healthcare provider.

Rare Side Effects

  1. Allergic Reactions: Although rare, some individuals may develop an allergic reaction to Omnaris. Symptoms may include hives, rash, itching, difficulty breathing, or swelling of the face, lips, tongue, or throat. Seek immediate medical attention if you experience any of these symptoms.
  2. Vision Changes: In very rare instances, Omnaris may cause blurred vision or other changes in vision. If you notice any visual disturbances, contact your doctor promptly.
  3. Persistent Headache: While headaches are typically a transient side effect, a small number of users may experience persistent or severe headaches. If this occurs, consult your healthcare provider.
  4. Thinning of Skin: Prolonged use of corticosteroid nasal sprays like Omnaris may lead to thinning of the nasal mucosa in rare cases. Your doctor will monitor this if you require long-term treatment.
  5. Delayed Wound Healing: Individuals undergoing surgery or with recent nasal injury should use Omnaris with caution, as corticosteroids may delay wound healing in rare cases.

Severe Side Effects

  1. Cataracts and Glaucoma: Long-term and high-dose use of corticosteroids may increase the risk of developing cataracts or glaucoma. Regular eye check-ups are essential during extended Omnaris use.
  2. Suppression of Immune System: Prolonged use of Omnaris can suppress the immune system, making you more susceptible to infections. If you notice frequent illnesses, consult your healthcare provider.
  3. Adrenal Insufficiency: In rare cases, corticosteroids like Omnaris can lead to adrenal insufficiency, a condition where the adrenal glands do not produce enough hormones. Symptoms may include fatigue, weakness, and weight loss.
  4. Growth Retardation in Children: Children using corticosteroid nasal sprays for an extended period may experience slowed growth. Your pediatrician will closely monitor your child’s growth during treatment.
  5. Osteoporosis: Prolonged use of high-dose corticosteroids may increase the risk of osteoporosis, a condition characterized by weakened bones.


As with any medication, it is essential to be aware of its interactions with other drugs, herbs, and foods to avoid potential adverse effects and ensure its optimal effectiveness.

Drug Interactions

  1. Antifungal Medications: Some systemic antifungal drugs, like ketoconazole, may increase the concentration of Omnaris in the body. This can lead to an increased risk of corticosteroid side effects. It’s crucial to inform your healthcare provider if you are taking antifungal medications.
  2. CYP3A4 Inhibitors: Medications that inhibit the enzyme CYP3A4 can also raise the levels of Omnaris in the body. This includes drugs like erythromycin, ritonavir, and grapefruit juice. Your doctor may need to adjust the dosage of Omnaris if you are using such medications concurrently.
  3. Other Nasal Products: The simultaneous use of other nasal sprays or decongestants may lead to excessive drying of the nasal passages or increased blood pressure. Consult your healthcare provider before using any other nasal products with Omnaris.
  4. Immunosuppressants: Taking immunosuppressive drugs along with Omnaris may weaken the immune system further, increasing the risk of infections. Ensure your doctor is aware of all the medications you are using.
  5. Certain Antibiotics: Some antibiotics, such as clarithromycin and telithromycin, can interfere with Omnaris metabolism. Inform your healthcare provider if you are prescribed any antibiotics.
  6. Aspirin and NSAIDs: Long-term use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of corticosteroid side effects. It’s advisable to limit the use of these medications unless specifically instructed by your doctor.

Herbal Interactions

  1. St. John’s Wort: This herbal supplement is known to induce CYP3A4 enzymes, which can accelerate the metabolism of Omnaris, reducing its efficacy. Avoid using St. John’s Wort while using Omnaris.
  2. Echinacea: Echinacea may stimulate the immune system, and using it with Omnaris can lead to an overactive immune response. It’s best to avoid using Echinacea while on Omnaris therapy.
  3. Licorice Root: Licorice root may cause potassium loss and increase the risk of low potassium levels when used with corticosteroids like Omnaris. Consult your healthcare provider before using licorice root supplements.
  4. Ginkgo Biloba: Ginkgo biloba can inhibit platelet aggregation, potentially increasing the risk of bleeding if used alongside Omnaris. Inform your doctor if you are using this supplement.
  5. Ginseng: Ginseng may have immunostimulatory effects, which can interact with the immunosuppressive properties of Omnaris. Avoid using ginseng supplements without medical guidance.

Food Interactions

  1. Grapefruit: Grapefruit and grapefruit juice can inhibit CYP3A4 enzymes, potentially increasing Omnaris levels in the body. It’s advisable to avoid consuming large quantities of grapefruit products while on Omnaris therapy.
  2. High-Fat Meals: Taking Omnaris with high-fat meals may delay its absorption, leading to delayed relief of allergic rhinitis symptoms. Try to administer Omnaris away from mealtimes for optimal results.

How to Use

By understanding how to use Omnaris correctly, you can experience optimal results and regain control of your daily life.

  1. Wash Your Hands: Before handling the nasal spray, wash your hands thoroughly with soap and water to prevent the spread of germs.
  2. Shake the Spray: Shake the Omnaris nasal spray gently before each use. This ensures that the medication is well-mixed for consistent dosing.
  3. Clear Your Nasal Passage: Gently blow your nose to clear any mucus or obstructions in your nasal passages.
  4. Prime the Pump: If you are using Omnaris for the first time or haven’t used it in the past seven days, you need to prime the pump. To do this, remove the cap, hold the bottle upright, and pump it a few times until a fine mist appears.
  5. Position the Spray: Hold the nasal spray upright with your fingers on the applicator and your thumb on the bottom of the bottle.
  6. Tilt Your Head: Tilt your head slightly forward and close one nostril with your finger.
  7. Administer the Spray: Place the nasal applicator in the open nostril and, with a firm, quick spray, press down on the pump to release the medication while inhaling gently.
  8. Breathe Out: Breathe out through your mouth to avoid blowing the medication back out of your nose.
  9. Repeat for the Other Nostril: Repeat the process for the other nostril.
  10. Avoid Blowing Your Nose: Try not to blow your nose immediately after using the nasal spray to allow the medication to work effectively.
  11. Clean the Applicator: After each use, clean the nasal applicator with a clean tissue and replace the cap.


Proper dosing is crucial for its effectiveness and to avoid potential adverse effects.

Initial Dosing of Omnaris

The initial dosing of Omnaris usually involves priming the nasal spray and then administering the correct number of sprays in each nostril. The number of sprays and the frequency of use will be determined by your healthcare provider based on your specific condition and medical history. Always follow your doctor’s instructions regarding the initial dosing.

Maintenance Dosing of Omnaris

After the initial dosing, you will move on to the maintenance phase. The maintenance dosing is designed to keep the allergy symptoms under control and prevent their recurrence. Here’s what you need to know about maintaining the correct dosage:

  1. Consistency is Key: It’s crucial to use Omnaris regularly and consistently as prescribed by your healthcare professional. Missing doses or irregular usage may lead to a decrease in its effectiveness.
  2. Long-Term Use: For many individuals, Omnaris is prescribed for long-term use during allergy seasons or as part of ongoing allergy management. It’s essential to continue using the medication as directed to experience sustained relief.
  3. Reassessment by Doctor: Your doctor may periodically reassess your symptoms and adjust the dosage if needed. If you experience any issues or changes in your allergy symptoms, consult your healthcare provider before altering the dosage.

Missed Doses

In the hectic pace of life, it’s not uncommon to miss a dose of medication. If you accidentally miss a dose of Omnaris, follow these guidelines:

  1. Take It as Soon as You Remember: If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed one and resume your regular dosing schedule. Avoid taking a double dose to make up for the missed one.
  2. Seek Professional Advice: If you’re unsure about what to do or have concerns about missed doses, don’t hesitate to contact your healthcare provider. They can provide personalized advice based on your situation.


An overdose of Omnaris is highly unlikely, especially when used as directed. However, if you suspect an overdose or accidentally use more than the prescribed amount, take the following steps:

  1. Stay Calm: While an overdose is rare, panicking can exacerbate the situation. Stay calm and focused.
  2. Seek Medical Attention: Contact emergency services or go to the nearest medical facility immediately.
  3. Do Not Induce Vomiting: Do not attempt to induce vomiting unless instructed to do so by medical professionals.
  4. Bring the Medication: If possible, bring the Omnaris nasal spray container with you to the healthcare facility.
  5. Follow Medical Advice: Cooperate with the healthcare professionals and follow their instructions carefully.


To ensure this medication remains potent and safe, it’s crucial to store it properly.

  • Store at Room Temperature: Keep Omnaris at room temperature and avoid exposing it to extreme heat or cold. The ideal storage temperature for this medication ranges between 20°C to 25°C (68°F to 77°F).
  • Protect from Direct Sunlight: Always store Omnaris in its original packaging to shield it from direct sunlight, which can compromise its effectiveness.
  • Keep Away from Moisture: Moisture can degrade Omnaris and reduce its efficacy. Store the medication in a dry place, away from humid environments like bathrooms.
  • Seal the Bottle Tightly: After each use, ensure the bottle is tightly closed to prevent air and moisture from entering, which can lead to contamination.
  • Avoid Freezing: Do not freeze Omnaris, as extreme cold can damage the medication and alter its composition.
  • Check Expiry Date: Always check the expiration date before using Omnaris. Discard the medication if it is past the expiry date to avoid any potential health risks.
  • Keep Out of Reach of Children: Store Omnaris in a secure location out of the reach of children and pets. Accidental ingestion can be harmful.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

Product was successfully added to your cart!