Invokana, with the generic name canagliflozin, falls under a class of medications known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. It is primarily prescribed to individuals with type 2 diabetes to help lower blood sugar levels.

It works by targeting the SGLT2 protein responsible for reabsorbing glucose in the kidneys. By inhibiting this protein, Invokana reduces glucose reabsorption and increases its excretion through urine. This action helps to lower blood sugar levels in patients with diabetes.

Unlike traditional diabetes medications that focus on insulin regulation, Invokana takes a different approach by targeting the kidneys. This novel mechanism of action not only helps in reducing blood sugar levels but also results in moderate weight loss due to the elimination of excess glucose calories through urine.

Type Two Diabetes

Type 2 diabetes, also known as non-insulin-dependent diabetes or adult-onset diabetes, is a condition that affects how your body metabolizes sugar (glucose). Glucose is an essential source of energy for the body’s cells, and insulin is a hormone produced by the pancreas that helps regulate the amount of glucose in the bloodstream.

In type 2 diabetes, the body either becomes resistant to the effects of insulin or doesn’t produce enough insulin to maintain normal blood sugar levels. This leads to elevated blood sugar levels, which can result in various health complications over time.

Warnings and Precautions

It is crucial for individuals taking Invokana to be aware of the potential risks and precautions involved in order to ensure their safety and well-being. By understanding the precautions and warnings, individuals can make informed decisions about their health.

Potential for Diabetic Ketoacidosis

Invokana has been associated with an increased risk of diabetic ketoacidosis (DKA), a serious condition that can lead to diabetic coma or even death if left untreated. DKA occurs when the body produces high levels of ketones, which are toxic acidic chemicals. Symptoms of DKA include excessive thirst, frequent urination, nausea, vomiting, abdominal pain, fatigue, and confusion. If you experience any of these symptoms while taking Invokana, seek immediate medical attention.

Risk of Genital Infections

Invokana has been linked to an increased risk of genital yeast infections in both males and females. It is important to maintain good hygiene and report any signs of infection, such as itching, burning, or unusual discharge, to your healthcare provider. Prompt treatment can help prevent the infection from worsening.

Hypotension and Dehydration

Invokana may cause a drop in blood pressure, leading to symptoms of dizziness, lightheadedness, or fainting. Additionally, it can increase the risk of dehydration. It is crucial to stay adequately hydrated while taking Invokana and be cautious when standing up or changing positions quickly to minimize the risk of falls.

Increased Risk of Urinary Tract Infections

Patients taking Invokana may be at a higher risk of developing urinary tract infections (UTIs). UTIs can cause discomfort, frequent urination, and a burning sensation during urination. If you experience any of these symptoms, it is important to seek medical attention for appropriate diagnosis and treatment.

Bone Fracture Risk

Long-term use of Invokana has been associated with an increased risk of bone fractures, particularly in the upper extremities. If you have a history of bone fractures or osteoporosis, it is essential to discuss this with your healthcare provider before starting Invokana. They can evaluate the potential risks and benefits of the medication for your specific situation.

Hypersensitivity Reactions

Some individuals may experience hypersensitivity reactions while taking Invokana. These reactions can range from mild skin rashes to severe allergic reactions, including swelling of the face, lips, tongue, or throat, which can be life-threatening. If you develop any signs of an allergic reaction, seek immediate medical attention.

Side Effects

It is essential to understand the potential side effects of any medication before using it, so let’s explore the common, rare, and severe side effects associated with Invokana.

Common Side Effects of Invokana

  • Frequent Urination: Invokana works by increasing the amount of glucose excreted in the urine, which can lead to more frequent urination.
  • Urinary Tract Infections (UTIs): Some individuals taking Invokana may be at an increased risk of developing urinary tract infections due to the higher sugar content in the urine.
  • Genital Yeast Infections: The increased sugar levels in the urine can create an environment favorable for the growth of yeast, leading to genital yeast infections.
  • Increased Thirst: Invokana can cause increased thirst as a result of increased urination.
  • Dehydration: Frequent urination can lead to dehydration if not properly managed. It is important to stay well-hydrated while taking Invokana.
  • Low Blood Pressure: Invokana may cause a decrease in blood pressure, especially when standing up from a sitting or lying position.

Rare Side Effects of Invokana

  • Ketoacidosis: In rare cases, Invokana may cause a serious condition called ketoacidosis, which is characterized by the buildup of ketones in the blood. Symptoms of ketoacidosis include excessive thirst, frequent urination, abdominal pain, fatigue, and fruity-scented breath. If you experience any of these symptoms, seek immediate medical attention.
  • Allergic Reactions: Some individuals may develop an allergic reaction to Invokana. Signs of an allergic reaction include rash, itching, swelling, severe dizziness, and difficulty breathing. If you experience any of these symptoms, seek immediate medical attention.
  • Hypersensitivity Reactions: Invokana may cause hypersensitivity reactions in rare cases. These reactions can manifest as skin rash, hives, swelling, or severe itching. If you develop any of these symptoms, discontinue the use of Invokana and consult your healthcare provider.
  • Kidney Problems: Invokana has been associated with an increased risk of kidney problems, including acute kidney injury. Symptoms of kidney problems may include changes in urination, swelling in the legs or feet, fatigue, and shortness of breath. If you experience any of these symptoms, seek medical attention promptly.
  • Bone Fractures: Rare cases of bone fractures, particularly in the bones of the upper leg, have been reported in individuals taking Invokana. If you experience unusual bone pain or fractures, inform your healthcare provider.
  • Fungal Infections: Although rare, Invokana has been associated with fungal infections of the skin and nails. If you notice any unusual changes in your skin or nails, consult your healthcare provider.

Severe Side Effects of Invokana

  • Pancreatitis: Invokana may cause inflammation of the pancreas, leading to a condition called pancreatitis. Symptoms of pancreatitis include severe abdominal pain, nausea, vomiting, and tenderness in the abdomen. If you experience these symptoms, seek immediate medical attention.
  • Lower Limb Amputation: There have been reports of lower limb amputations, such as toe, foot, or leg amputations, in individuals taking Invokana. If you notice any new pain, tenderness, sores, ulcers, or infections in your lower limbs, contact your healthcare provider immediately.
  • Cardiovascular Events: In some cases, Invokana has been associated with an increased risk of cardiovascular events such as heart attack or stroke. If you experience symptoms such as chest pain, shortness of breath, sudden numbness or weakness, or difficulty speaking, seek immediate medical attention.
  • Impaired Kidney Function: Invokana can affect kidney function, leading to decreased kidney function or kidney failure. Symptoms of impaired kidney function may include changes in urination, swelling, fatigue, and shortness of breath. If you experience these symptoms, seek medical attention promptly.
  • Urinary Tract Obstruction: In rare instances, Invokana may cause urinary tract obstruction, leading to difficulty or pain during urination. If you experience any urinary difficulties or severe pain, consult your healthcare provider immediately.
  • Severe Dehydration: Prolonged or severe dehydration can occur in some individuals taking Invokana. If you experience symptoms such as extreme thirst, dry mouth, weakness, dizziness, or lightheadedness, seek medical attention.

Drug Interactions

Invokana is a medication used to treat type 2 diabetes by controlling blood sugar levels. However, like any medication, it is crucial to understand its potential interactions with other drugs to ensure patient safety and effectiveness.

Diuretics

Diuretics, commonly known as water pills, are often prescribed to manage conditions like high blood pressure and heart failure. When combined with Invokana, diuretics may enhance the diuretic effect, leading to increased urine production and the potential for dehydration. It is crucial to monitor fluid and electrolyte levels in patients taking both Invokana and diuretics.

Insulin

Insulin is a hormone used to control blood sugar levels in individuals with diabetes. When Invokana is used in conjunction with insulin, it may increase the risk of hypoglycemia (low blood sugar). Close monitoring of blood glucose levels is essential to adjust insulin dosages accordingly and prevent complications.

Sulfonylureas

Sulfonylureas are another class of medications used to treat type 2 diabetes. When combined with Invokana, sulfonylureas may increase the risk of hypoglycemia. Regular blood sugar monitoring is crucial when these medications are used together.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

NSAIDs are commonly used to manage pain and inflammation. However, when taken with Invokana, NSAIDs may decrease the diuretic effect of Invokana and potentially increase the risk of fluid retention. Patients should be cautious when using NSAIDs while taking Invokana and report any unusual symptoms to their healthcare provider.

Beta-blockers

Beta-blockers are medications used to manage conditions like high blood pressure and heart disease. When combined with Invokana, beta-blockers may mask some of the symptoms of hypoglycemia, making it more difficult to recognize and treat. Close monitoring of blood glucose levels is essential for patients taking both medications.

Angiotensin-Converting Enzyme (ACE) Inhibitors

ACE inhibitors are commonly prescribed for conditions such as high blood pressure and heart failure. When combined with Invokana, ACE inhibitors may increase the risk of hypotension (low blood pressure). Regular blood pressure monitoring is important to prevent complications.

Warfarin

Warfarin is an anticoagulant medication used to prevent blood clots. When taken with Invokana, warfarin may increase the risk of bleeding. Frequent monitoring of prothrombin time (PT) and International Normalized Ratio (INR) is necessary for patients taking both medications.

Dosing

When it comes to managing diabetes, medication plays a crucial role in controlling blood sugar levels. One such medication is Invokana, which has gained popularity for its effectiveness in treating type 2 diabetes. However, it is essential to understand the correct dosage of Invokana and its potential side effects to ensure safe and effective treatment.

Recommended Dosage

The recommended starting dose of Invokana is 100 milligrams (mg) once daily, taken before the first meal of the day. Your healthcare provider may adjust the dosage based on your individual needs and response to the treatment. The maximum recommended daily dose is 300 mg.

Invokana can be taken with or without food, but it is important to take it consistently at the same time each day to maintain a steady level of the medication in your body. Swallow the tablet whole with a glass of water and do not crush or chew it.

Overdose of Invokana

In the event of an overdose of Invokana, it is crucial to seek immediate medical attention. Overdosing on Invokana can lead to serious complications and requires prompt intervention. Common symptoms of an overdose may include:

  • Excessive thirst
  • Increased urination
  • Fatigue
  • Rapid heartbeat
  • Abdominal pain
  • Nausea and vomiting
  • Hypotension (low blood pressure)
  • Electrolyte imbalances

If you suspect an overdose or experience any of these symptoms, contact your local emergency services or go to the nearest emergency room. It is essential to provide healthcare professionals with accurate information about the medication taken to ensure appropriate treatment.

Missed Dose of Invokana

If you happen to miss a dose of Invokana, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

It is important to maintain a consistent dosing schedule to optimize the effectiveness of Invokana in controlling your blood sugar levels. Setting a reminder or using alarms on your phone can help you remember to take your medication at the designated times.

Storage

By following the guidelines outlined here, you can ensure the effectiveness and safety of your medication.

  • Store at Room Temperature: Invokana should be stored at room temperature between 68°F and 77°F (20°C and 25°C). Avoid exposing the medication to extreme heat or cold, as it may affect its potency.
  • Keep Away from Moisture: Moisture can damage Invokana, so it’s essential to store it in a dry place. Avoid storing it in the bathroom or any area with high humidity.
  • Protect from Light: Invokana should be kept in its original container, which is designed to protect the medication from light. Store it away from direct sunlight or intense artificial light.
  • Avoid Freezing: Do not freeze Invokana. Freezing temperatures can alter the composition of the medication, rendering it ineffective.
  • Keep Out of Reach of Children: Store Invokana in a secure location, out of the reach of children and pets. This will prevent accidental ingestion and ensure their safety.
Product was successfully added to your cart!