This is a prescription medication that is used to treat certain kinds of cancer. Gleostine is a brand name used for the medication Lomustine. It is classified into a group of drugs called alkylating agents. It’s generally prescribed for treating brain cancer in patients who have had either radiation or surgery previously. It can slow cancer cell growth or even stop it completely.

Gleostine can be used on its own or with other medications to treat brain cancer as well as different types of cancer and Hodgkin’s disease. It disrupts the growth of cancer cells, and those cells are eventually destroyed.

Precautions and Warnings with Gleostine

This medication is made to treat the fast-growing cancer cells in the body, but it can also affect other cells. This can cause several health risks for the patient. It’s important to let your doctor know if you’ve ever had liver disease, bone marrow suppression, breathing problems, lung disease, or kidney disease.

Gleostine can put you at a higher risk of developing other cancer types, including leukemia. The effects of this medication may still be seen on the body months or even years after it was taken. It can depress your immune system and make you more likely to get an infection. Severe infections can happen as long as six weeks after you’ve finished taking this medication. You may need blood testing weekly for six weeks or more after you’ve taken this medication. If you develop bruises quickly, have unusual bleeding, or see symptoms of an infection, talk to your doctor immediately.

Taking this medication can affect your fertility, whether you’re male or female. However, birth control should be used while taking this medication. If either the father or mother is taking this medication, the baby can be harmed. Use birth control for at least two weeks after you finish taking Gleostine if you’re a woman. If you’re a man, keep using birth control for at least 14 weeks after you’ve taken this medication.

It generally isn’t taken during pregnancy because it can cause harm to the baby. You can talk to your doctor about effective birth control methods. It’s also important not to breastfeed while taking this medication. After you’ve finished this medication, wait a minimum of two weeks before you breastfeed.

Don’t take this medication if you’ve ever had an allergic reaction. Ensure your doctor knows your complete medical history and whether you’ve ever had any blood disorder or infection. Taking this medication makes you more at risk of getting infections. Stay away from people with an easily spread infection like chickenpox, flu, or Covid-19.

Before you have any vaccinations, make sure the practitioner knows you’re taking this medication. It would be best to stay away from anyone who has recently gotten a live vaccine. These include the inhaled flu immunization. If you’re going to have surgery, let the doctor or dentist know you take Gleostine.

It’s essential to try to protect yourself from being cut or bruised while taking this medication. Be careful when handling sharp objects and avoid contact sports and other dangerous activities.

Gleostine Side Effects

A number of side effects can be caused by taking Gleostine. If they bother you, you can discuss the effects with your doctor. One of the worst effects is that it can cause a patient to develop leukemia or another type of cancer. You may not have every side effect reported, and you may have few or no side effects while you take it.

Common Side Effects

The most common side effects include:

  • Chest pain
  • Sore throat
  • Hair loss
  • Bleeding gums
  • Unusual bruising or bleeding
  • Shortness of breath
  • White spots, ulcers, or sores in the mouth and on the lips
  • Being unusually weak or tired
  • Nausea
  • Infections
  • Vomiting

Uncommon Side Effects

Some of the less common side effects that may indicate a health problem include:

  • Confusion
  • Pale skin
  • Decrease in urination
  • Tarry, black stools
  • Hoarseness or coughing
  • Slurred speech
  • Swelling of the lower legs or feet
  • Blood in stools or urine
  • Difficult or painful urination
  • Shortness of breath
  • Pain in the lower back or side

Drug Interactions With Gleostine

There aren’t any known interactions between other medications and this drug. However, telling your doctor everything you’re taking is still essential. Please list all of your medications as well as their dosages. Don’t stop taking any medication without talking to your doctor. When you list your medications, include any herbs you take or other OTC supplements.

Gleostine Strengths and Dosages

This medication has several strengths on the market, each with a different color. You may have to take two or more capsules of various strengths and colors to make your dosage when you take your dose. The strengths are 5 mg, 10 mg, 40 mg, and 100 mg capsules. Your specific dosage can depend on several factors, including the results of your blood tests.

5 mgYellow and yellow
10 mgWhite and white
40 mgWhite and green
10 mgGreen and green

When this medication is administered, it’s given in the form of one dose every six weeks. When you handle the capsules, use disposable gloves. Please don’t open the capsule or let it get onto your skin. If a capsule is broken, don’t use it. Avoid breathing in any powder from this medication.

FAQs With Gleostine

Can you take Gleostine during pregnancy or breastfeeding?

No, it shouldn’t be taken during either. Use effective birth control while on this medication. If you get pregnant while on it, tell your doctor right away. This medication can harm a baby.

Can you drink alcohol with Gleostine?

There is no contraindication between this medication and alcohol.

Are there side effects with Gleostine?

Yes, many side effects can occur. Effects such as nausea, hair loss, and bleeding gums can occur in patients.

Can I take Gleostine if I already have an infection?

Taking this while you have an infection can make it harder to heal from that condition. It can also make the infection worse. Please stay away from anyone with contagious diseases while taking it. If this medication is greatly needed, it can be taken with an infection.

Is Gleostine an expensive medication?

Yes, it’s costly. However, it’s only administered once every six weeks.

Why is Gleostine prescribed?

Gleostine is a medication used to treat both cancerous brain tumors and Hodgkin’s Lymphoma.

Can I get a live vaccine while taking Gleostine?

It isn’t a good idea to get this type of vaccine during treatment with this medication because it can lower your immune system response. It would be best to stay away from people who recently had such a vaccine.

How do I Gleostine this medication?

Keep the bottle closed and away from extreme temperatures. It should be stored at room temperature and kept away from moisture. Make sure the cap stays on tightly.

I got some Gleostine on my skin- what should I do?

Please wash the area with soap and water.

Are there alternative medications I can use instead of Gleostine?

Several other medications can be used to treat brain tumors and Hodgkin’s Lymphoma. These include pembrolizumab and bleomycin. If you’re prescribed Gleostine, the doctor expects this medication to be the best for your condition. If it causes dangerous effects, you might be changed to a different medication.

What is the cost of Gleostine in America?

The price of this drug made headlines a few years ago as it was raised by 1,500% over a short period. It remains a costly drug today. The price of each dose depends a lot on the strength of the dose and where you get the prescription filled—five capsules at the 100 mg strength average about $6,500.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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