Emcyt is a medication prescribed for the treatment of metastatic prostate cancer. It has an active ingredient estramustine phosphate that breaks down in the body into estradiol and a nitrogen mustard, which is a type of chemotherapy drug.

This medication prevents the growth of cancer cells that depend on hormones for their growth. Emcyt is used specifically when the cancer has spread to other parts of the body and is no longer responding to other treatments.

How Does Emcyt Work?

Estramustine uses a dual mode of action, combining nitrogen mustard and estrogen hormones, to treat cancer. Nitrogen mustard prevents the proliferation of cancer cells by damaging the cells’ DNA and disrupting the genetic material of the dividing cancer cells.

On the other hand, estrogen hormone targets the cancer cells that rely on testosterone hormone for their growth. When estramustine is metabolized in the body, it stimulates the release of estrogen, which reduces testosterone levels, thereby slowing down the growth of cancer cells.

Precautions and Warnings of Emcyt

Patients should take certain precautions when using Emcyt because it might lead to the development of serious medical conditions or may worsen side effects if these warnings are ignored. Some precautions and warnings to pay attention to include:

  • Blood Pressure: Patients using Emcyt may experience high blood pressure during treatment. As such, patients should regularly monitor blood pressure and report if the results are high.
  • Thrombosis: If you are under the medication of Emcyt, you may experience an elevated likelihood of thrombosis that can be fatal or non-myocardial infarctions. Report to your doctor if you experience signs of blood clots like swelling pain, or warmth in one leg.
  • Allergic Reactions: Inform your doctor about any allergic reaction you have or if you are allergic to any of its ingredients.
  • Medical History: Inform your doctor if you’re suffering from kidney or liver conditions before taking Emcyt because it might lead to renal insufficiency.
  • Gynecomastia: Prolonged use of Emcyt may lead to the development of gynecomastia as well as impotence in males.

Side Effects of Emcyt

Patients may experience several side effects after taking Emcyt. If the side effects persist or become severe, then contact your doctor for medical assistance.

Common Side Effects

  • Leg cramps
  • Elevated blood pressure
  • Loss of appetite
  • Breast enlargement
  • Difficulty breathing
  • Stomach upset
  • Nausea

Severe Side Effects

  • Blood clots in the lungs
  • Heart attack
  • Chest pain or pressure
  • Sudden numbness in one side of the body
  • Mood changes such as depression
  • Redness in the arms or legs

Drug Interactions With Emcyt

The interaction of Emcyt with other medications may alter the drug’s therapeutic outcomes and the safety of the treatment regimens.

Understanding the potential interactions of other medications with Emcyt is important in optimizing patient care and minimizing the risks associated with combined therapy such as superinfection and toxicity.

Drug Interaction
LisinoprilThe interaction between Lisinopril and Emcyt may lead to an increased risk of excessive bleeding.
Calcium Channel Blockers (verapamil)Combining Emcyt and verapamil, a type of calcium channel blocker, may result in addictive hypotensive side effects such as dizziness and increased hypotension.
AlteplaseConcurrent use of Emcyt with alteplase (Cathflo) may lead to an enhanced risk of bleeding complications
WarfarinEmcyt may enhance the effects of warfarin, increasing the risk of nose bleeding and blood in the urine or stool.
Nonsteroidal anti-inflammatory drugsEmcyt medication can interact with NSAIDs and cause gastrointestinal bleeding, renal impairment, and ulcers.
Anticoagulants (heparin)Using anticoagulant medication like heparin and Emcyt may potentiate the anticoagulant effects of heparin such as hemorrhage at injection site and increased bleeding.

Strengths and Dosages of Emcyt

Your doctor will prescribe Emcyt dosage depending on your weight, which can be adjusted upwards or downwards if you add or lose weight.

AgeDosage No. of times a day
Adult14mg per kg3 to 4 times a day

It is advisable to swallow Emcyt when you have not eaten anything, preferably about an hour before eating or some 2 hours after you’re done with your meal. Take the drug wholly with a glass full of water (8 ounces or 240 milliliters).

Do not use milk, any products containing milk products, or calcium-rich food or drugs when taking the medication. Pregnant women should avoid coming into contact with the dust from the capsule because it can get into their bodies through the skin or lungs and harm the unborn baby.

Cost of Emcyt in America

Emcyt is only available as a drug brand name, making it an expensive medication. On average, this antineoplastic drug costs around $1,174 for 140mg oral capsules containing a supply of 100 capsules. The quoted price is for cash-paying customers and does not apply to insurance plans.

Emcyt Alternatives

While there’s no generic version of Emcyt, there are other drugs that patients can use in place of Emcyt. Alternatives are great options for clients who can’t afford Emcyt or those who cannot tolerate this medication. Some of the alternative drugs include;

  • BicalutamideThis medication inhibits the androgen hormones thus preventing the proliferation of cells that depend on these hormones for growth. Bicalutamide attaches itself to the androgen receptor in a competitive manner, inhibiting androgens’ effects on prostate tumor cells without stimulating the receptor.
  • Zytiga (Abiraterone Acetate) – It prevents the CYP17A1 enzyme, which is necessary for the production of androgens. By preventing androgen production, abiraterone suppresses tumor growth in prostate cancer.
  • Lupron Depot (Leuprolide) – Yet another alternative medication that treats prostate cancer, endometriosis, breast cancer, and uterine fibroids.
  • Some other alternatives of Emcyt include; Zytiga, Xtandi, Casodex, and Eleada.

FAQs of Emcyt

Is Emcyt safe if I have a liver or kidney problem?

No. Emcyt is not safe to take if you have liver or kidney problems because your body may experience challenges in metabolizing the medication, which may cause adverse kidney side effects like fluid buildup.

How long do I need to take Emcyt?

Your doctor might recommend you take the medication for a minimum of 1 to 3 months (30 to 90 days) before they determine its effectiveness. Medication will continue if they ascertain the benefits of the therapy.

What are the side effects of Emcyt?

Despite its effectiveness, Emcyt has several side effects, including loss of appetite, nausea, stomach upset, heart attack, breast tenderness or enlargement, and swelling of the feet and hands.

Is Emcyt a chemotherapy drug?

Yes. Emcyt is a chemotherapy drug that functions in two ways. It combines chemotherapy nitrogen mustard and estrogen to treat prostate cancer in males.

How should I take Emyct?

Swallow Emcyt with a glass of water on an empty stomach, at least an hour before eating or some 2 hours after meals. Do not take the medication with milk or anything that has milk-based products.

What medication interacts with Emyct?

Do not take Emyct if you are currently on medication for liver conditions or live virus vaccines. Also, avoid taking vitamins, calcium products, and non-dietary supplements, because they may interact with the medication causing adverse side effects.

What should I know before taking Emcyt?

Before taking Emcyt, be sure to inform your doctor about any allergies you may have or if you’re addicted to any of its ingredients. Also, let them know about your medical conditions or any drugs you might be taking as they may affect the efficacy and safety of this medication.

What is the indication of Emcyt?

The medication is indicated for the use of relieving symptoms of patients with advanced or worsening prostate cancer.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

Product was successfully added to your cart!