Constella is a guanylate cyclase-C agonist used to treat long-term constipation and irritable bowel syndrome that stems from constipation.

This prescription drug works by boosting the digestive tract’s fluid levels. With more fluids, the body’s stool gets softer. With softer stool, waste and food have an easier time moving through the digestive system and bowel movements happen more frequently.

Constella also makes the digestive system’s nerves less sensitive to pain. This makes having a bowel movement easier and relieves constipation.

Precautions and Warnings with Constella

Before you start taking constella, you should make sure your doctor is aware of any allergies or medical conditions you currently have. If you are pregnant, breastfeeding, planning to get pregnant, or planning to begin breastfeeding, you should inform your doctor.

Children who take constella may suffer from diarrhea and other serious side effects linked to this medication. Constella is not recommended for anyone under the age of 18 to consume.

Only adults should take constella. Diarrhea is very common when consuming this medication. If diarrhea becomes very watery or too frequent, this can cause dehydration. If you experience severe diarrhea upon taking constella, let your doctor know and stop taking this prescription drug.

If you have linaclotide allergies or digestive tract blocks, do not take constella.

Constella Side Effects

Constella impacts the digestive system and may come with different side effects.

Mild Side Effects

If you begin to have mild side effects after taking Constella, they may go away with time as your body gets used to this medicine. If the following side effects persist, inform your doctor:

  • Nausea
  • Gassiness
  • Vomiting
  • Abdominal bloating

Severe Side Effects

If you begin to notice severe side effects from Constella, you should immediately let your doctor know. If you think you’re having a medical emergency, call 911 right away. Severe side effects from constella are not common.

Severe side effects from Constella can include the following:

  • Intense or new abdominal pain
  • Watery stool

Drug Interactions with Constella

Before you start taking constella, you should let your doctor know about any vitamins, supplements, medications, or herbs that you’re on or planning to start taking.

Constella may interact with certain substances. You should inform your doctor if you’re consuming any of the following substances:

  • Nicotine
  • Caffeine
  • Alcohol
  • Street drugs

Strengths and Dosages of Constella

Constella is available in capsules of 72, 145, and 290 µg. For chronic constipation, adults are generally advised to take 145 µg one time each day. Adults with irritable bowel syndrome and constipation are generally prescribed 290 µg to be taken one time per day.

This medication should be at least 30 minutes ahead of the person’s first meal and on an empty stomach. Constella should be taken orally with water and swallowed whole. Do not chew, split, break, or crush Constella .

If you miss a dose of Constella , stick with the prescription schedule that your doctor gave you. Do not take an extra dose of Constella to make up for a missed dose. This can lead to stronger side effects or other problems.

Constella Alternatives

At this time, there is not a generic alternative to Constella . It is only available as a brand-name drug, but the following alternatives to constella exist:

FAQs of Constella

What is Constella?

Constella is a medicine and guanylate cyclase-C agonist designed to treat irritable bowel syndrome and chronic constipation.

How does Constella work?

Constella works by increasing fluid levels in the digestive tract which then makes stool softer and gives food and waste a smoother transition through the digestive system. Constella also reduces nerve pain in the digestive system.

How do I take Constella?

Constella should be swallowed whole, on an empty stomach, and with a glass of water.

What time of day should you take Consteall?

Constella should be taken 30 minutes before a person’s very first meal each day.

How long does it take for Constella to start working?

Constella often starts to produce positive results within six to eight weeks. Some people taking this medicine notice changes in more or less time.

Who makes Constella?

Constella is made by Ironwood Pharmaceuticals.

What is the cost of Constella in America (without insurance)?

A 30-capsule supply of constella costs about $610 without insurance at most pharmacies across America.

Why is Constella so expensive?

Constella is expensive because there is no available generic version of this drug and it only exists as a brand-name prescription medicine.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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