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Intrarosa (Prasterone Vaginal Inserts)

Intrarosa is a prescription vaginal insert used in postmenopausal women to treat moderate to severe pain during sexual intercourse caused by menopausal changes in and around the vagina. It is a local vaginal therapy containing prasterone (DHEA).

We only dispense medications with a valid prescription from a licensed prescriber.

All prescriptions are reviewed and verified before dispensing. Orders may be delayed or declined if prescription details are missing, do not match the patient information on file, appear altered, or are expired. We may also refuse service if we believe an order is intended for resale or redistribution.

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What You Receive

From $23.41 – $98.56

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Delivery times may vary based on location and prescription verification.

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Intrarosa Key Facts

What Intrarosa is

Intrarosa is a prescription vaginal insert (not an oral tablet) that contains prasterone 6.5 mg. It is inserted vaginally using the provided applicator.

What it’s used for

Intrarosa is indicated for moderate to severe dyspareunia (pain during sexual intercourse), a symptom of vulvar and vaginal atrophy due to menopause.

How it works

Prasterone is an inactive endogenous steroid that is converted into active androgens and/or estrogens. The exact mechanism of action of Intrarosa for this condition is not fully established.

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Intrarosa Safety Overview

Your prescriber may also review your medical history and medication list before treatment.

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Intrarosa Warnings & Precautions

Intrarosa has a limited but important safety profile in the label, including a contraindication for undiagnosed abnormal genital bleeding and a warning related to current or past breast cancer history.

Do not use Intrarosa if:

Key warnings to know

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Side Effects and When to Get Help

The most commonly reported side effects in the label are vaginal discharge and abnormal Pap smear findings. Side effects are not the same for everyone, so contact your prescriber if symptoms are persistent, worsening, or concerning.

Possible side effects may include

Get urgent help right away for

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Interactions

The Intrarosa full prescribing information does not list a dedicated Drug Interactions section, but the patient information instructs patients to tell their healthcare provider about all medicines and supplements they use.

Interactions you should discuss with your prescriber include

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Intrarosa Drug Facts

CategoryDetails
Brand NameIntrarosa
Drug ClassSteroid (prasterone; vaginal therapy)
IndicationModerate to severe dyspareunia due to vulvar and vaginal atrophy associated with menopause
Dosage FormsVaginal insert
Strengths6.5 mg prasterone per vaginal insert
Contraindications / Who should not use itUndiagnosed abnormal genital bleeding
Administration TimingInsert 1 vaginal insert vaginally once daily at bedtime using the provided applicator
Key WarningsBreast cancer history concern (prasterone is metabolized to estrogen); use only in postmenopausal women
StorageStore at 41°F to 86°F (5°C to 30°C), room temperature or refrigerated
AlternativesVaginal estrogen options may include Vagifem or Yuvafem, Estrace Vaginal Cream, Estring, or Imvexxy; oral Osphena may be considered in some patients depending on history and symptoms
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Helpful Information

Checklist

How To Buy Intrarosa Online

1

Select Your Prescribed Intrarosa Dosage & Strength

Choose the strength and quantity that matches your prescription, then add it to your cart. Orders are limited to a 90-day supply per fill.

2

Complete Checkout

Ensure your shipping and contact information is correct so your order can be processed without delays.

3

Submit Your Intrarosa Prescription

Upload your prescription at checkout. If you need a transfer, provide your prescriber or current pharmacy details and we will request it on your behalf.

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Prescription & Dispensing Standards

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FAQs

What is Intrarosa used for?

Intrarosa is used in postmenopausal women to treat moderate to severe pain during sexual intercourse caused by menopausal changes in and around the vagina.

Use 1 vaginal insert once daily at bedtime, inserted into the vagina with the applicator provided. Each applicator is for one-time use only.

Intrarosa contains prasterone (DHEA), which is converted in the body into active androgens and/or estrogens. The label notes that prasterone is metabolized to estrogen.

The most common side effects listed in the label are vaginal discharge and abnormal Pap smear findings.

No. Do not use Intrarosa if you have vaginal bleeding that has not been checked by your healthcare provider. Postmenopausal women with undiagnosed persistent or recurring genital bleeding should be evaluated before treatment.

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Ordering & Prescription FAQs

Do I need a prescription?
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