Tadalis, also known by its generic name Tadalafil, is a medication primarily used to treat erectile dysfunction (ED) in men. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. The drug works by relaxing the blood vessels and increasing blood flow to certain areas of the body, facilitating an erection during sexual stimulation.

This medication is available in the form of oral tablets that are taken by mouth with or without food. The dosage may vary based on individual health conditions and needs.

Tadalis is manufactured by Ajanta Pharma, a renowned pharmaceutical company based in India. Ajanta Pharma is committed to producing high-quality generic medications and has gained recognition for its expertise and commitment to patient well-being.

Tadalafil is primarily prescribed for the treatment of erectile dysfunction, a condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Apart from ED, Tadalis is also used to manage symptoms of benign prostatic hyperplasia (BPH) in some cases.

As a PDE5 inhibitor, blocks the action of the enzyme PDE5 in the penis, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). By inhibiting PDE5, Tadalis helps to maintain higher levels of cGMP, leading to increased blood flow to the penis during sexual stimulation. This enhanced blood flow results in a firmer and more prolonged erection.

Numerous clinical trials and studies have demonstrated the effectiveness of Tadalis in treating ED and PAH. The drug has shown significant success rates in helping individuals achieve and sustain erections, leading to improved sexual performance and satisfaction. For patients with PAH, Tadalis has been instrumental in alleviating symptoms and enhancing their overall well-being.

My Rx Outlet only has the 20mg Tadalis tablets available. If you are looking for other Tadalfil generics, be sure to take a look at: Tadacip, Megalis, Forzest & Adcrica.

Tadalis Availability

Tadalis, although widely used and approved in many countries, is not available for commercial sale in the United States. This restriction is mainly due to certain patent issues and market regulations. Mauritius, a country known for its robust pharmaceutical regulations, allows the distribution and sale of Tadalis.

MyRxOutlet.com offers a convenient and trustworthy prescription fulfillment service, allowing individuals in America to purchase Tadalis legally and safely with discreet packaging and reliable delivery services.. Please note, a valid and legal prescription from a US prescriber is needed in order to use our services. We do not ship out medication without a proper prescription that illustrates the need for the medication.

While Tadalis can provide positive outcomes, it is essential to be aware of the potential risks and take necessary precautions. This article aims to shed light on the important warnings and precautions associated with Tadalis usage.

Warnings and Precautions

Tadalis, or tadalafil, is a valuable medication for men experiencing erectile dysfunction. However, its usage requires careful consideration of warnings and precautions to ensure safe and effective treatment. Consultation with a healthcare professional, awareness of potential side effects, adherence to dosage guidelines, and understanding its limitations are essential for a positive experience with Tadalis.

Consultation with a Healthcare Professional

Before considering Tadalis or any other medication for ED, it is vital to have a thorough consultation with a qualified healthcare professional. This step is crucial as they will assess your medical history, current medications, and overall health to determine if Tadalis is suitable for you. People with certain medical conditions or taking specific medications may not be suitable candidates for Tadalis.

Medical History

Individuals with certain medical conditions, such as heart problems, liver or kidney disease, retinitis pigmentosa, or a history of stroke, should exercise caution when using Tadalis. The medication can exacerbate these conditions or interact with other treatments, leading to adverse effects.

Cardiovascular Conditions

Individuals with pre-existing cardiovascular conditions, such as heart disease and hypertension, should exercise caution when using Tadalis. The increased blood flow caused by the medication can put extra strain on the heart, leading to potential complications.

Liver and Kidney Disorders

Patients with liver or kidney disorders may require dosage adjustments while using Tadalis. Impaired liver or kidney function can affect how the drug is metabolized and eliminated from the body, potentially increasing the risk of side effects.


Inform your healthcare provider about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Certain medications may interact with Tadalis, leading to adverse effects or reduced efficacy.

Allergic Reactions

Those with known allergies to tadalafil or any inactive ingredients in Tadalis should avoid using this medication. Allergic reactions can range from mild skin rashes to severe anaphylaxis, a life-threatening condition that requires immediate medical attention.


Elderly individuals may be more sensitive to the effects of Tadalis. A lower starting dosage may be recommended for this age group.

Vision Impairment

Rare cases of non-arteritic anterior ischemic optic neuropathy (NAION) have been reported in patients using Tadalis. If you experience sudden vision loss in one or both eyes, discontinue the medication and seek medical attention immediately.

Avoiding Alcohol and Grapefruit Juice

Consuming alcohol and grapefruit juice while using Tadalis can interact with the medication and lead to adverse effects. Alcohol may reduce the effectiveness of Tadalis, while grapefruit juice can increase the concentration of the drug in the bloodstream, intensifying side effects. It is best to avoid these substances while using Tadalis.

Psychological Considerations

Erectile dysfunction can have psychological causes as well. Consider seeking counseling or therapy in addition to medical treatment for a comprehensive approach to managing the condition.

Pregnancy and Breastfeeding

Tadalis is not intended for use by women. Pregnant or breastfeeding women should not handle the medication due to potential adverse effects on the unborn or nursing child.

Do’s and Don’ts

  • Do not take Tadalis more than once a day.
  • Do not crush or split the tablet.
  • Do not take Tadalis with other ED medications simultaneously.

Side Effects

Tadalis, or Tadalafil, is an effective medication for treating erectile dysfunction. While it offers relief to many individuals, it’s crucial to be aware of potential side effects. Most users experience only mild and temporary reactions, but some rare and severe side effects can occur. If you experience any unusual symptoms or reactions while using Tadalis, it’s essential to seek medical attention promptly. Remember, open communication with your healthcare provider is vital to ensure the safe and effective use of this medication.

Common Side Effects of Tadalis

The following side effects are considered common and usually mild. They tend to subside as your body adjusts to the medication:

  1. Headache: One of the most frequently reported side effects of Tadalis is a mild to moderate headache. This reaction is usually short-lived and can be managed with over-the-counter pain relievers.
  2. Indigestion: Tadalis can cause gastrointestinal discomfort, leading to symptoms like indigestion or upset stomach. Taking the medication with food may help alleviate this issue.
  3. Muscle Pain: Muscle pain or myalgia is another common side effect that may occur. Gentle stretching and over-the-counter pain relievers can help alleviate discomfort.
  4. Back Pain: In some cases, individuals may experience mild to moderate back pain while taking Tadalis. This discomfort usually subsides on its own.
  5. Facial Flushing: Some individuals may experience facial flushing or a sensation of warmth in the face and neck after taking Tadalis. This is a common side effect and is not typically a cause for concern.

Rare Side Effects of Tadalis

Although uncommon, some individuals may experience the following rare side effects:

  1. Vision Changes: In rare cases, some individuals may experience changes in vision, such as blurred vision, sensitivity to light, or difficulty differentiating between blue and green colors. If this occurs, seeking medical attention is essential.
  2. Hearing Loss: While extremely uncommon, there have been reports of sudden hearing loss associated with the use of Tadalis. If any hearing impairment is noticed, medical help should be sought promptly.
  3. Priapism: Priapism is a rare but serious side effect of Tadalis, characterized by a prolonged and painful erection lasting more than four hours. It necessitates immediate medical attention to prevent potential tissue damage.
  4. Allergic Reactions: While exceedingly rare, some individuals may develop allergic reactions to Tadalis. Signs of an allergic reaction include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. Seek emergency medical help if you experience these symptoms.

Severe Side Effects of Tadalis

Severe side effects of Tadalis are rare but require immediate medical attention. If you experience any of the following, seek medical help promptly:

  1. Cardiovascular Issues: Tadalis can have an impact on cardiovascular health, especially in individuals with pre-existing heart conditions. It may cause a drop in blood pressure, which could be dangerous for those taking certain heart medications.
  2. Priapism: Priapism is a severe but rare side effect characterized by a prolonged and painful erection lasting more than four hours. It requires immediate medical attention to prevent permanent damage to the penis.
  3. Vision and Hearing Loss: In severe cases, Tadalis has been linked to non-arteritic anterior ischemic optic neuropathy (NAION), a rare condition that can cause sudden vision loss. Additionally, total hearing loss has been reported in some users.
  4. Severe Hypotension: Tadalis can lead to a sudden drop in blood pressure, resulting in dizziness, lightheadedness, or fainting. Individuals with low blood pressure should use Tadalis cautiously.


Always consult with your healthcare provider before starting Tadalis, and be sure to provide a complete list of your current medications, herbal supplements, and dietary habits. Being informed and proactive about potential interactions can help you maximize the benefits of Tadalis while minimizing any risks.

Drug Interactions

Before taking Tadalis, it is crucial to consult with a healthcare professional about any medications you are currently taking. Certain drugs can interact with Tadalis and cause adverse effects or reduce its effectiveness. Here are some common drugs that may interact with Tadalis:

  1. Nitrates: One of the most critical drug interactions to be cautious of is with nitrate-based medications. Taking Tadalis concurrently with nitrates, commonly prescribed for chest pain or heart conditions, can cause a dangerous drop in blood pressure. This combination may lead to dizziness, fainting, or even a life-threatening situation. It is crucial never to mix Tadalis with any form of nitrates.
  2. Alpha-Blockers: Alpha-blockers, used to treat hypertension and prostate enlargement, can also interact with Tadalis. When taken together, they can cause a significant reduction in blood pressure, leading to adverse effects. If you are on alpha-blockers, consult your healthcare provider before using Tadalis.
  3. Antibiotics: Certain antifungal medications and antibiotics can interfere with the metabolism of Tadalis, affecting its efficacy and potentially causing adverse effects. It is advisable to inform your doctor about any ongoing antifungal or antibiotic treatment before starting Tadalis.
  4. Antifungal Medications: Azole antifungals, like ketoconazole and itraconazole, can also interact with Tadalis and affect its metabolism in the body.

Herbal Interactions

While herbal remedies are often perceived as natural and safe, they can still interact with prescription medications like Tadalis. Some herbal supplements may cause adverse effects or reduce the effectiveness of the medication. Here are some herbal interactions to be cautious of when taking Tadalis:

  1. Ginseng: Ginseng, a well-known herbal supplement for energy and stamina, may also interact with Tadalis. It’s important to be cautious about combining these substances, as it could lead to unwanted effects on blood pressure and overall health.
  2. St. John’s Wort: St. John’s Wort, a popular herbal remedy for depression, may influence the metabolism of Tadalis. This could alter the drug’s effectiveness or lead to unexpected side effects. If you are taking St. John’s Wort, discuss it with your doctor before using Tadalis.
  3. Yohimbe: Yohimbe is another herbal supplement sometimes used for erectile dysfunction. Combining it with Tadalis may result in adverse reactions or worsen existing health conditions. Seek professional medical advice before using Yohimbe alongside Tadalis.
  4. Horny Goat Weed: Another herb believed to enhance sexual performance, but it can interact with Tadalis and cause adverse reactions.

Food Interactions

While Tadalis can be taken with or without food, certain foods may influence how the medication is absorbed and metabolized in the body. Here are some food interactions to consider:

  1. Grapefruit: Grapefruit and grapefruit juice can interfere with the metabolism of Tadalis, leading to increased drug levels in the body. This could potentially intensify side effects or make them more likely to occur. It is advisable to avoid grapefruit products while using Tadalis.
  2. Fatty Foods: Consuming large amounts of fatty foods can delay the absorption of Tadalis, leading to a delayed onset of action. To experience the medication’s benefits promptly, consider a light meal or none at all before taking Tadalis.
  3. Alcohol: While Tadalis itself does not have specific interactions with alcohol, excessive alcohol consumption can impair sexual function and diminish the effectiveness of the medication. Moderation is key to ensure the desired results.

Tips for Managing Interactions

  1. Always inform your doctor about all medications and supplements you are taking.
  2. Avoid combining Tadalis with nitrates, alpha-blockers, and certain antiviral drugs.
  3. Be cautious with herbal remedies like St. John’s Wort, ginseng, and yohimbe.
  4. Steer clear of grapefruit products and excessive alcohol consumption while on Tadalis.
  5. Follow your doctor’s advice for a safe and effective Tadalis experience.


Before delving into the specific storage guidelines, it’s important to understand why proper storage is crucial for medications like Tadalis. Improper storage can lead to the degradation of active ingredients, reducing the drug’s efficacy. Additionally, exposure to certain environmental factors may even render the medication harmful or ineffective. To ensure that Tadalis delivers the desired results when needed, following the right storage conditions is paramount.

Store in a Cool, Dry Place

Tadalis should be stored in a cool, dry place away from direct sunlight and moisture. High temperatures and humidity can accelerate the degradation process of the medication. Avoid storing it in the bathroom or near the kitchen sink, as the heat and moisture levels in these areas are typically high.

Keep Away from Children and Pets

To prevent accidental ingestion or misuse, keep Tadalis out of reach of children and pets. The medication should only be used by the individual for whom it is prescribed. If accidental ingestion occurs, seek immediate medical attention.

Do Not Freeze

Freezing Tadalis is strictly prohibited, as it can alter the chemical composition of the drug. If exposed to freezing temperatures, the medication may lose its effectiveness. Always keep the medication at room temperature.

Use the Original Packaging

Keep Tadalis in its original packaging, as it is designed to protect the medication from external factors that could compromise its quality. The blister packs and bottles are specifically designed to maintain the drug’s stability.

Avoid Excessive Light Exposure

Tadalis should be shielded from excessive light exposure. UV rays and intense artificial light can degrade the active ingredients. Therefore, store the medication in a dark cupboard or drawer.

 Check Expiry Date

Before using Tadalis, always check the expiration date printed on the packaging. Expired medications may not only be ineffective but could also pose potential health risks. If the medication is past its expiry date, dispose of it properly and obtain a new supply.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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