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Surolan (Miconazole Nitrate, Polymyxin B, Prednisolone Acetate)
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Surolan is a suspension medication for treating otitis externa and dermatitis caused by yeasts, fungi, bacteria, and ear mites in animals only. It is a veterinary-prescribed topical for dogs and cats with antifungal, antibacterial, and anti-inflammatory properties.
Surolan is FDA-approved and is a brand name manufactured by Elanco. The active ingredients are: Polymyxin B, miconazole, and prednisolone.

Labeled Warnings of Surolan
Surolan Otic Suspension is a prescription medication for treating ear infections in animals only. It is not for use in humans. Keep this and all medicines away from children.
Do not administer orally for otic use only.

How to use Surolan Otic Suspension
Administer this drug exactly as directed by your veterinarian. If you have any questions or doubts, contact your veterinarian or pharmacist.
- Shake well before using.
- Apply only on a clean external ear.
- Do not allow medication into your pet’s mouth, eyes, or nose.
- Please do not allow the animal to lick or groom the treated ears for at least 20 to 30 minutes after application.
- Wear gloves or wash your hands after handling the medication.

Surolan Precautions and Warnings
Surolan contains antibiotic and antifungal drugs, which may cause resistance. To help minimize resistance, use this medication for the complete treatment prescribed, even if the animal seems to feel better or symptoms disappear. Administer Surolan precisely as your veterinarian prescribes it.
- Surolan is not for use in humans.
- This drug is only for external use; do not administer it orally.
- Do not allow the drug to enter the animal’s eyes or mouth.
- Before starting treatment, thoroughly examine the external ear canal to ensure the tympanic membranes are not perforated.
- Please consult with your veterinarian if overgrowth of non-susceptible bacteria or fungi occurs.
- Contact your veterinarian if the infection is not healing or getting worse.
- There is no research regarding the effect of the drug on pregnant bitches.
- Avoid using other ear medications by talking to your veterinarian first.

Surolan Side Effects
Talk to your veterinarian in case of any changes in your pet’s behavior, such as:
- Loss of appetite
- Vomiting
- Diarrhea
- Increasingly worse ear pain
- Head tilt
- Walking in circles
- Uncommon thirst
- Excessive urination
- Hair issues or redness at the application site.

Surolan Drug Interactions
Certain drugs should be used with caution when given with Polymyxin B/miconazole/prednisolone solution, including but not limited to medications that increase ototoxicity (e.g., aminoglycoside antibiotics)
Inform your veterinarian about any other drugs your pet takes before starting any new treatment.

Strengths and Dosages of Surolan
Follow your veterinarian’s instructions before using Surolan. The usual dose is five drops of Surolan in the ear canal twice daily, regardless of weight, for at least seven days. Surolan provides effective treatment for otitis externa, is FDA-Approved, and has been in the market with proven effectiveness for over 30 years.

Surolan Alternatives
Some alternatives to Surolan include Zymox Otic Enzymatic Solution Hydrocortisone, which contains no hydrocortisone and has no reported side effects.
Panolog Ointment is a drug particularly useful in treating acute and chronic otitis.
Another drug used for chronic ear infections is Otomax Ear Drops Suspension.

Surolan FAQ
What problems could my dog or cat have with Surolan?
- Surolan is a safe medication as long as you take the following precautions:
- Do not allow the medication into your pet’s eyes or mouth.
- Do not use if the animal has damaged ear drums.
- Call your veterinarian if the infection does not subside or gets worse.
- If you notice altered behavior in your pet, contact your veterinarian. Symptoms could include appetite loss, vomiting, diarrhea, hearing loss, ear pain, head tilt, walking in circles, increased thirst, or frequent urination.
How do you use Surolan?
- Shake well before use.
- Clean and dry the ears before application.
- Do not allow your dog, cat, or other animals to lick or groom the infected ears for 20 to 30 minutes after application.
- Wash your hands after handling this medication.
Is it essential for my dog or cat to finish all of the Surolan?
Surolan contains an antibiotic and an antifungal that may cause resistance. It is essential to continue treatment as long as your veterinarian prescribes, even if the pet is feeling better.
What should I know about Surolan before using it on my pets?
Surolan is an FDA-approved prescription medication for animals only. It is essential to complete the treatment for the number of days prescribed by your veterinarian.
What should I talk about with my veterinarian before using Surolan?
Tell your veterinarian if you suspect your pet has allergies. Do not use it on pets with damaged eardrums.
What happens if I miss a dose of Surolan?
Apply the missed dose as soon as you remember. If it’s close to the next programmed dose, skip the one you forgot and apply the next according to your regular schedule. Do not double-dose.
What happens if I overdose my pet on Surolan?
An overdose is very rare. If you suspect you used a much more significant than regular dose or that the pet has swallowed the drug, contact your veterinarian.
How long does it take for Surolan to take effect?
This medication will act promptly, in no more than 2 hours, but it may take 1 to 2 days to notice the effects. Its moderate duration means that its effects may last a few days after the last dose.
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IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.