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Neupro (Rotigotine)
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Neupro is a range of transdermal patches that treat Parkinson’s disease. It is also prescribed to treat Restless Legs Syndrome (RLS). Neupro contains rotigotine, which acts as a dopamine agonist. It imitates the action of dopamine. Dopamine serves as a messenger substance in the parts of the brain that control the movement and coordination of the body.
Pakinson’s disease causes dopamine-producing cells to die, which reduces the amount of dopamine level to decrease. This causes uncontrollable movement of the limbs.
Neupro constantly delivers rotigotine through the skin into the bloodstream. The substance stimulates the brain as dopamine would, leading to patients controlling their movement.
However, scientists have yet to fully understand how Rotigotine is effective in treating RLS. Research has shown that dopamine functions in the brain, and the symptoms are improved by the continuous flow of Rotigotine in the brain.
Precautions and Warnings with Neupro
The effects of Neupro on pregnant women have not been proven. Therefore, it should not be used during pregnancy unless it is safe for both the mother and the child. You should contact your healthcare provider if you get pregnant while taking the medicine.
The medicine may reduce the quantity of breast milk in women, and it could pass into the baby, thus affecting the infant’s health. It is unknown if it is safe for children’s use as well.
You should inform your doctor of any medical conditions or allergies you may have or medications you are taking before you begin using a medication.
A doctor may not prescribe Neupro if you have a history of:
- Allergies
- Behavior changes
- Drowsiness
- Cardiac conditions
- Melanoma
- MRI and cardioversion
- Mobility issues
- Neuroleptic Malignant Syndrome
- Sudden onset of sleep
Neupro Side Effects
Side effects are unwanted responses of the body to medicines. They can be mild or severe, and they can be temporary or long-lasting. Like any other medicine, Neupro has side effects, which are as follows:
The medication is documented to affect daily activities, as people are known to fall asleep after using the medicine. It can occur anytime during treatment with Rotigotine, even if you have used this medication for a prolonged period. You should refrain from driving or participating in other activities until you have discussed this matter with your doctor.
Neupro may increase or decrease the patient’s blood pressure and lead to dizziness, lightheadedness, nausea, sweating, and fainting. This is likely when you first start the medication, when your dose is increased, or when you get up suddenly. You should get up slowly when rising from a sitting or lying position to reduce your risk.
You should consult with your doctor if you need to check your blood pressure while using this medication.
Common Side Effects
You should contact your healthcare provider if you are experiencing the following symptoms after using Neupro.
- Redness/itching
- Swelling
- Headache
- Increased sweating
- Trouble sleeping
- Fatigues
- Lightheadedness
- Drowsiness
- Dizziness
- Loss of appetite
- Vomiting
- Nausea
Serious Side Effects
You should seek immediate medical attention if you are experiencing the following when using Neupro:
- New or worsening uncontrolled movements
- Fast heartbeat
- Unusual weight gain
- Swelling ankles/feet
- Unusual strong urges (to gamble, indulge in sexual behavior)
- Fainting
- Severe dizziness
- Mental changes (confusion, agitation, hallucinations)
Drug Interactions with Neupro
Drug interaction refers to a substance affecting how a drug behaves in the body. The substances, along with food and beverages, can make a drug less effective or more potent when it is taken with other medications.
Neupro affects how your body processes other drugs and vice versa. It is important to inform your doctor or caregiver about which medicines you are taking before starting treatment with this medication.
Neupro is documented to interact with the following medicines:
- Trazodone
- Azilect (Rasagiline)
- Cymbalta (Duloxetine)
- Clonazepam
- Gabapentin
- Melatonin
- Lyrica (Pregabalin)
- Ropinirole
- Pramipexole
- Tramadol
- Tizanidine
Strengths and Dosages of Neupro
Neupro comes in patches that are applied to your skin every day. They are available in the following strengths, which are administered in milligrams (mg) per 24 hours:
- 1 mg/24 hours
- 2 mg/24 hours
- 3 mg/24 hours
- 4 mg/24 hours
- 6 mg/24 hours
- 8 mg/24 hours
| Dosage | System Size | Content Level |
| 1 mg/24 hours | 5 cm2 | 2.25 mg |
| 2 mg/24 hours | 10 cm2 | 4.5 mg |
| 3 mg/24 hours | 15 cm2 | 6.75 mg |
| 4 mg/24 hours | 20 cm2 | 9 mg |
| 6 mg/24 hours | 30 cm2 | 13.5 mg |
| 8 mg/24 hours | 40 cm2 | 18 mg |
There are different ways Neupro can be applied for treating Parkinson’s disease.
The started dose, which is recommended to patients with early-stage Parkinson’s disease, is a 2 mg/24-hour patch. The daily dose should not be over 16 mg/24 hours.
Patients with early stages of Restless Legs Syndrome are recommended a 1 mg/24-hour patch applied daily. It may be increased to a maximum of 3 mg/24 hours.
You should start by ensuring your skin is clean, dry, and free of cuts or irritation. It is better to pick a different area every day, rotating sites to avoid skin irritation.
You remove the patch from its pouch and peel off the protective liner. Press the patch firmly with your palm for 30 seconds to ensure it sticks well. Wash your hands thoroughly after applying the patch. It should be replaced within 24 hours and used at the same time for consistency.
Cost of Neupro In America
The average cost of a 30-patch Neupro box is between $771.96 to $1,022.06, without insurance. The price may vary depending on the pharmacy, insurance coverage, and treatment plan.
Why are Neupro patches so expensive?
Neupro is expensive in the United States for several reasons. The medicine treats complex conditions like Parkinson’s disease and Restless Legs Syndrome and requires extensive research and development. The medicine has high manufacturing costs, and the market for such medication is limited.
Neupro Alternatives
Neupro does not have generic versions available on the market. This is due to the expiration of patents held by the original manufacturer and regulatory approval processes. Therefore, you should consult with your healthcare provider if you plan on switching to an alternative version of the medicine.
Your healthcare provider may switch to alternative medicine due to different reasons (efficacy and availability) for effective treatment, as they have the same function.
Your doctor may substitute Neupro patches with these medicines:
- Ropinirole
- Pramipexole
- Pregabalin
- Sinemet
- Carbidopa/levodopa
- Clonazepam
- Gabapentin
- Rasagiline
- Rytary
- Amantadine
FAQs of Neupro
What is Neupro?
Neupro is a medicine available as a transdermal patch that contains the active ingredient Rotigotine. It is classified into a group of drugs called dopamine agonists.
What is Neupro used for?
Neupro treats symptoms of Parkinson’s disease (poor muscle control, muscle spasms, tremors, stiffness) and Restless Leg Syndrome.
Where do you apply the Neupro patch?
The Neupro patch is typically applied to clean, dry, intact skin on the stomach, thigh, hip, upper arm, or shoulder. It should be applied to a different area each day to avoid skin irritation.
When will Neupro go generic?
Neupro became eligible for patent challenges on May 9, 2011, and the expected date for it to go generic is March 1, 2032. It can be premature or postponed due to patent challenges or licensing.
How long does it take for Neupro patches to work?
Neupro patches may become effective within a few hours to days after starting treatment. However, the full therapeutic effect may take several weeks of consistent use.
How to wean off Neupro patches?
It’s essential to gradually reduce the dose under medical supervision to minimize withdrawal symptoms and other effects. Your doctor will provide a tapering schedule tailored to your individual needs and health condition.
Our Guarantee For Buying Neupro From A Canadian Pharmacy Partner
At MyRx Outlet, we are committed to delivering safe, high-quality medications that you can trust. We adhere to strict regulations in every country we operate in, ensuring that your order is handled by a licensed Canadian pharmacy or a trusted partner overseas. Each medication has been legally approved by Health Canada or other respected authorities. To purchase Neupro at a discounted rate, call 1-888-551-2467.
IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.
