Tizanidine is a medication that relieves a patient of spasms, muscle tightness, and cramping. It’s used when a medical issue like a spinal injury, brain injury, or multiple sclerosis causes these. This medication can’t cure the problem but can often make physical therapy and other treatments more effective. It’s a short-acting medication that can block the impulses sent to the brain that cause pain sensations.

This medication works on the patient’s central nervous system and relaxes muscles. It’s a prescription medication that is available by tablet or capsule. It’s sometimes prescribed to patients for off-label use, such as convulsions, insomnia, and migraines.

Precautions and Warnings of Tizanidine 

If you switch between the capsule and tablet forms or change your food intake when you take it, you may experience more side effects or less effectiveness. Talking to your doctor about properly taking this medication and following their instructions is essential. Talk to your doctor if you notice any side effects or if the medication isn’t working.

Tell your doctor if you have ever had low blood pressure or kidney or liver disease. Please don’t drink alcohol while taking this medication, as it can worsen side effects. If you’re pregnant, there is the potential for risk because we don’t have information about whether it poses a danger to the baby. It’s generally not a good idea to breastfeed while taking it but talk to your doctor about the possible risks versus the benefits you could get from using it.

You will need to be monitored while using tizanidine. The doctor will look for any side effects and check how well the medication works. Blood tests may be necessary to ensure the medication isn’t causing unwanted changes to your body. It’s possible to get lightheaded or dizzy when you stand up fast. Fainting may even happen in these situations. When you take this medication, get into the habit of standing up slowly to avoid these problems.

Taking a CNS depressant, a medication that makes you less alert or sleepy, with this medication can make the side effects worse. Alcohol is a CNS depressant. Others include medicines for colds or allergies, antihistamines, and hay fever medications. It’s also essential to avoid other muscle relaxants, narcotics, prescription pain medications, sedatives, sleeping medications, and tranquilizers. If you need dental work, tell the dentist that you take this medication. It may react with certain dental anesthetics.

Because this medication can cause you to be drowsy or dizzy, you need to know how it affects you before you drive a car or operate any other dangerous machinery. It can also affect your vision, making it even more dangerous to operate heavy machinery.

Please don’t stop taking tizanidine abruptly without talking to your doctor about it. You may need to have the doctor help you taper off this medication before you stop taking it. This can prevent your condition from getting worse and presenting symptoms of withdrawal.

Tizanidine Side Effects

There are many different side effects possible when you take tizanidine. It’s also possible to have hallucinations from this medication. If this happens, tell your doctor right away. If you have chronic vomiting or have light-colored stools, tell your doctor. These can be serious. A pain in the top right of the stomach can also be severe. Some patients have side effects when they first start the medication, but they go away over time. If yours bother you, your doctor may have advice about how to reduce them. Or, you may need to change medications.

If you notice that you have dark urine, pale stools, yellowing skin or eyes, or a loss of appetite, you may have a severe liver problem. It’s also possible to have a severe allergic reaction to this medication, and this can include an anaphylactic reaction. The symptoms include having difficulty breathing or swallowing, itching, a rash, or swelling of the mouth, hands, or face. If this happens, seek emergency medical care right away.

If you get a dry mouth from this medication, you can chew gum or eat sugarless candy. You can also eat ice chips to try to moisturize your mouth. If this symptom lasts over two weeks, talk to your doctor about the problem. Extended dry mouth can raise the risk of developing dental disease.

Some are mild, while others may be moderate or severe. Please let your doctor know if you have side effects that bother you or worsen over time.

Common Side Effects

  • Headache
  • Chest discomfort or pain
  • Nervousness
  • Unusual fatigue
  • Nausea and vomiting
  • Urination burning or pain
  • Dry mouth
  • Dizziness
  • Weakness
  • Drowsiness

Rare Side Effects

  • Weight gain
  • Skin itching
  • Blurry vision
  • Tenderness of the upper right stomach
  • Irregular heartbeat
  • Kidney stones
  • Ful-like symptoms
  • Shortness of breath
  • Sore throat
  • Constipation

Tizanidine Drug Interactions

Certain medications can interact poorly with tizanidine. These include both ciprofloxacin (found in Ciloxan) and fluvoxamine. Neither of these should be taken along with tizanidine. It’s also important not to take other medications that can cause drowsiness, such as sleeping medications, opioid medications, anxiety medication, seizure medication, or other muscle relaxers. These can add to the depressant effect and can cause serious side effects. This can even be fatal.

Tell your doctor if you take zileuton, acyclovir (found in Zovirax), birth control medications, ticlopidine, antibiotics, heart rhythm, blood pressure, or stomach acid medications. All of these can have interactions with tizanidine. There may also be over-the-counter medications and herbal supplements that can interact with it. Tell your doctor everything you take, even if it’s OTC.

Tizanidine Strengths and Dosages

This medication comes in two forms: tablets and capsules. The tablets come in 2 mg and 4 mg, and the capsules come in 2 mg, 4 mg, and 6 mg. The dosage usually starts at 2 mg every six to eight hours or as otherwise directed. The doctor may increase the dosage by 2 or 4 mg for a few days before it is raised again. When the medication has a significant benefit, the correct dose is found. There should be a substantial reduction in spasms.

Tablets: 2 mg, 4 mg
Capsules: 2 mg, 4 mg, 6 mg

FAQs of Tizanidine

Can you drink alcohol while on this medication?

No, it can be dangerous to do so. Both act as depressants, and they could cause you to breathe too slowly.

Does this medication come in a liquid form?

No, it’s only available as a tablet or capsule.

Can you breastfeed while taking tizanidine?

No, it’s best not to do so.

Can this medication cause you to hallucinate?

This isn’t a common side effect, but it does happen. If this happens, tell your doctor right away. You might be directed to taper off this medication.

Can you stop taking tizanidine all at once?

No, unless there are serious side effects or an allergic reaction, it’s best to talk to your doctor and work with a plan for tapering off slowly. Otherwise, you could go through withdrawal symptoms.

Can you take sleeping pills with this medication?

No, it’s best not to take sleeping pills or pain pills while you take this medication.

Can tizanidine make you uncoordinated?

Yes, this is a typical effect of the medication. If you need to do anything dangerous, it might be best not to take this medication. That’s especially true when you need good balance.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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