Brilinta, also known as ticagrelor, is an oral antiplatelet medication designed to prevent blood clots in patients with ACS. It is commonly prescribed to individuals who have experienced a heart attack or unstable angina (chest pain caused by reduced blood flow to the heart). Brilinta works by inhibiting platelet aggregation, which reduces the risk of blood clot formation and subsequent blockage in the arteries. This mechanism of action sets Brilinta apart from other antiplatelet medications, making it a preferred choice for many healthcare providers.

Its unique mechanism of action, combined with its numerous benefits, makes it a trusted choice for patients and healthcare providers worldwide. By inhibiting platelet aggregation, Brilinta significantly reduces the risk of cardiovascular events and improves long-term outcomes. If you or a loved one have been diagnosed with ACS, consult your healthcare provider to determine if Brilinta is the right choice for you.

The Benefits of Brilinta

Reduced Risk of Heart Attack

One of the primary benefits of Brilinta is its ability to significantly reduce the risk of heart attacks in patients with ACS. Clinical trials have demonstrated that Brilinta, when used as prescribed, can effectively lower the incidence of recurrent heart attacks. This makes it an invaluable tool in preventing further cardiac complications and ensuring a healthier future for patients.

Decreased Risk of Stroke

In addition to reducing the risk of heart attacks, Brilinta also offers protection against strokes. By inhibiting platelet aggregation, Brilinta helps prevent the formation of blood clots that could potentially travel to the brain and cause a stroke. This aspect of Brilinta’s efficacy makes it an essential medication for patients at risk of cardiovascular events.

Improved Blood Flow to the Heart

Brilinta enhances blood flow to the heart by preventing platelet clumping and clot formation in the arteries. This improved blood circulation ensures that the heart receives an adequate supply of oxygen and nutrients, reducing the strain on the cardiovascular system. By promoting better blood flow, Brilinta aids in the overall well-being of individuals with ACS.

Enhanced Survival Rates

Studies have shown that patients treated with Brilinta have better survival rates compared to those on other antiplatelet medications. The ability of Brilinta to minimize the risk of subsequent cardiac events plays a crucial role in improving long-term outcomes and prolonging life expectancy. Choosing Brilinta is a proactive step towards a healthier and more secure future.

Brilinta, also known by its generic name Ticagrelor, belongs to a class of medications called antiplatelet drugs. It works by preventing blood platelets from sticking together, reducing the risk of blood clots that can lead to heart attacks or strokes. It is typically prescribed along with aspirin and is available in tablet form for oral administration.

Warning and Precautions

While Brilinta can be highly effective in managing these conditions, it is important to be aware of the warning signs and take necessary precautions to ensure safe usage.

Possible Allergic Reactions

Allergic reactions to Brilinta are rare but can occur. If you experience symptoms such as hives, difficulty breathing, swelling of the face or throat, or rash, it is crucial to seek immediate medical attention. Inform your healthcare provider about any known allergies or sensitivities before starting Brilinta.

Increased Risk of Bleeding

Brilinta can increase the risk of bleeding, which can range from minor cuts to more severe bleeding complications. It is important to take precautions and avoid activities or situations that may result in injury. Notify your doctor if you experience prolonged bleeding, blood in urine or stool, or unusual bruising.

Surgery and Dental Procedures

If you are scheduled for surgery or dental procedures, it is crucial to inform your healthcare provider about your Brilinta usage. They may advise you to temporarily discontinue the medication to minimize the risk of bleeding during the procedure. However, it is important not to stop taking Brilinta without your doctor’s approval, as it can increase the risk of heart-related complications.

Side Effects

Brillinta can cause various side effects, ranging from mild to severe. It is crucial to understand that not everyone who takes this medication will experience side effects, and the severity and occurrence may vary from person to person. It is always advisable to consult with your healthcare provider if you have any concerns or questions about the side effects of Brillinta.

Common Side Effects

  1. Headache: One of the most frequently reported side effects of Brillinta is a headache. This is generally a mild and temporary symptom that resolves on its own. If you experience persistent or severe headaches, it is important to consult your doctor.
  2. Nausea: Brillinta may cause feelings of nausea, often accompanied by a loss of appetite. These symptoms are typically mild and tend to improve over time. If nausea persists or becomes severe, it is advisable to seek medical attention.
  3. Bleeding: Brillinta is known to increase the risk of bleeding. This can manifest as nosebleeds, prolonged bleeding from minor cuts, or easy bruising. It is important to monitor any unusual bleeding and inform your healthcare provider promptly.
  4. Shortness of Breath: Some individuals may experience shortness of breath or difficulty breathing while taking Brillinta. If you develop any respiratory symptoms, it is crucial to seek immediate medical attention, as this could be a sign of a serious allergic reaction.
  5. Dizziness: Brillinta may cause dizziness or lightheadedness in some individuals. It is advisable to avoid activities that require mental alertness or physical coordination until you know how the medication affects you.
  6. Diarrhea: Brillinta can occasionally lead to diarrhea, which is usually mild and self-limiting. If you experience severe or persistent diarrhea, it is important to consult your healthcare provider.
  7. Rash: Skin rash or itching is a potential side effect of Brillinta. If you develop a rash that is severe, persistent, or accompanied by other symptoms such as fever or swelling, it is essential to seek medical attention.

Serious Side Effects

While rare, Brillinta can cause serious side effects that require immediate medical attention. It is crucial to be aware of these potential complications and seek prompt medical care if you experience any of the following:

  1. Severe Allergic Reactions: Brillinta can trigger severe allergic reactions in some individuals. Symptoms may include swelling of the face, lips, tongue, or throat, difficulty breathing, and hives. If you develop any of these symptoms, call emergency services immediately.
  2. Bleeding Complications: Brillinta’s antiplatelet action increases the risk of bleeding. In rare cases, it may cause serious bleeding, such as gastrointestinal bleeding, intracranial bleeding, or bleeding that requires medical intervention. If you experience signs of severe bleeding, such as blood in your stool, black or tarry stools, vomit that looks like coffee grounds, or sudden severe headache, seek immediate medical attention.
  3. Liver Problems: Although rare, Brillinta has been associated with liver problems. If you experience symptoms such as yellowing of the skin or eyes (jaundice), dark urine, or persistent nausea and vomiting, contact your healthcare provider promptly.
  4. Breathing Difficulties: Brillinta can rarely cause serious breathing difficulties, such as asthma-like symptoms or wheezing. If you develop sudden or severe breathing problems, seek immediate medical attention.
  5. Heart-related Complications: In rare cases, Brillinta may cause heart-related complications, including irregular heartbeat (arrhythmias) or heart attack. If you experience chest pain, rapid or irregular heartbeat, or any other signs of heart problems, seek emergency medical care.

Drug Interactions

It is important to understand the potential drug interactions associated with Brillinta to ensure its safe and effective use.

Antiplatelet Drugs

Brillinta belongs to the antiplatelet drug class, and its interaction with other antiplatelet medications should be carefully monitored. Combining Brillinta with other drugs that have antiplatelet effects, such as Dipyridamole or Plavix, can increase the risk of bleeding. Your healthcare provider will assess the benefits and risks of such combinations and adjust your medication regimen accordingly.


When Brillinta is used in combination with anticoagulant medications (such as Arixta, Fragmin and Lixiana) , it can further increase the risk of bleeding. Anticoagulants work by inhibiting blood clotting, and combining them with Brillinta may lead to excessive bleeding. Close monitoring of bleeding parameters is crucial if you are prescribed both Brillinta and anticoagulant therapy.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

NSAIDs, including Nevanac and Celebrex, are commonly used to relieve pain and reduce inflammation. However, when taken together with Brillinta, they may diminish the drug’s antiplatelet effects and increase the risk of cardiovascular events. It is advisable to consult your healthcare provider before using NSAIDs while on Brillinta therapy.

Proton Pump Inhibitors (PPIs)

Proton pump inhibitors, such as Prevpac or Dexilant, are often prescribed to reduce stomach acid production and prevent gastric ulcers. However, concomitant use of PPIs with Brillinta may decrease the effectiveness of Brillinta in preventing blood clots. Your doctor may recommend alternative medications or adjust the dosage to minimize any potential interactions.

CYP3A4 Inhibitors and Inducers

Brillinta is primarily metabolized by the liver enzyme CYP3A4. Drugs that inhibit or induce this enzyme can significantly impact the concentration of Brillinta in the body. CYP3A4 inhibitors, like ketoconazole or erythromycin, can increase the levels of Brillinta, potentially leading to an increased risk of side effects. On the other hand, CYP3A4 inducers, such as rifampin or St. John’s wort, may reduce the effectiveness of Brillinta. Your healthcare provider will consider these interactions when prescribing Brillinta and adjust the dosage accordingly.

Certain Antidepressants

Some antidepressant medications (such as Zoloft and Effexor), can interfere with the antiplatelet effects of Brillinta. This interaction may increase the risk of clotting and diminish the therapeutic benefits of Brillinta. It is essential to inform your doctor about any antidepressant therapy you are undergoing to avoid potential interactions.


To ensure the efficacy and safety of Brillinta, it is crucial to follow the recommended dosages.

Recommended Dosages

The standard dosage of Brillinta for adult patients is an initial loading dose of 180 mg, followed by a maintenance dose of 90 mg twice daily. The loading dose is usually administered orally, while the maintenance dose can be taken with or without food. It is essential to swallow the tablets whole, without crushing or chewing them.

Factors Affecting Dosage

Several factors can influence the dosages of Brillinta prescribed to an individual. These factors may include the patient’s medical history, concurrent medications, age, weight, and renal function. Healthcare professionals carefully evaluate these factors to determine the appropriate dosage for each patient, ensuring optimal therapeutic outcomes while minimizing the risk of adverse effects.

Overdose Symptoms

While adhering to the prescribed dosages is crucial, accidental or intentional overdose can occur. It is important to be aware of the potential symptoms of Brillinta overdose. Brillinta overdose can increase the risk of bleeding, which can be life-threatening. It is essential to contact emergency services or your healthcare provider if you suspect an overdose.  If you experience any of the following symptoms after taking Brillinta, seek immediate medical attention:

  • Severe bleeding or bruising
  • Blood in urine or stools
  • Vomiting blood or material that resembles coffee grounds
  • Unusual fatigue or weakness
  • Fainting or dizziness

Missed Dose

If you accidentally miss a dose of Brillinta, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of adverse effects.

If you have any concerns or questions about a missed dose, consult your healthcare provider for guidance. They can provide personalized advice based on your specific situation.


When it comes to taking any medication during pregnancy, it is important to balance the potential benefits with the potential risks. While Brilinta is generally safe for most individuals, including pregnant women, it is essential to consult with your healthcare provider before starting or continuing any medication regimen. Your doctor will consider your specific situation and determine if the benefits of taking Brilinta outweigh the potential risks to both you and your baby.

Extensive research on the safety of Brilinta during pregnancy is limited. This is due to ethical considerations that prevent conducting extensive clinical trials involving pregnant women. However, available data from animal studies and a limited number of human cases provide some insight.

Animal studies have shown no evidence of harm to the developing fetus when Brilinta is administered during pregnancy. However, it is important to remember that animal studies do not always directly translate to humans. Therefore, caution is still warranted.


To maintain the integrity of the medication, it is recommended to store Brilinta in its original container. The packaging is designed to protect the tablets from exposure to light, moisture, and air, which can potentially degrade the medication. Additionally, the original container provides essential information about the medication, such as expiration date and dosage instructions.

Brilinta should be stored at room temperature, typically between 68°F and 77°F (20°C and 25°C). Avoid exposing the medication to extreme temperatures, such as excessive heat or cold. Keep it away from direct sunlight, heaters, radiators, and other heat sources. Fluctuations in temperature can affect the stability and potency of Brilinta.

Moisture can compromise the quality and effectiveness of Brilinta. It is essential to keep the medication away from areas with high humidity, such as bathrooms and kitchens. Additionally, make sure the container is tightly closed to prevent moisture from entering. If the tablets come in contact with water or any other liquid, they may become damaged and unsafe to use.

While some medications require refrigeration, Brilinta should not be stored in the refrigerator. The moisture and cold temperatures in the fridge can negatively impact the tablets’ stability. It is best to keep Brilinta at room temperature as mentioned earlier.

When storing any medication, including Brilinta, it is crucial to keep it out of the reach of children and pets. Brilinta contains active ingredients that can be harmful if ingested accidentally. Store the medication in a secure location, such as a locked cabinet or a high shelf, to prevent access by children or pets.

It is important not to transfer Brilinta tablets to another container, such as a pillbox or a different pill bottle. The original packaging is designed to provide the necessary protection and information about the medication. Transferring the tablets to another container can lead to confusion and compromise the medication’s stability.


Proper disposal of medications is crucial for several reasons. Firstly, it helps prevent accidental ingestion or misuse of the medication by children, pets, or adults who may not be aware of its potential dangers. Secondly, disposing of medications responsibly helps protect the environment by preventing them from entering water sources or contaminating soil.

There are several safe and convenient methods for disposing of Brilinta:

  1. Drug Take-Back Programs: One of the easiest and safest ways to dispose of Brilinta is through drug take-back programs. These programs are often organized by local pharmacies, community centers, or law enforcement agencies. They provide designated drop-off locations where you can safely dispose of your medications. Check with your local authorities or pharmacies for information on drug take-back programs in your area.
  2. FDA Guidelines for Flushing: In some cases, when there are no drug take-back programs available, the FDA recommends flushing certain medications down the toilet or sink. This method is specifically for medications that have the potential to be extremely harmful or fatal if ingested by someone other than the intended patient. However, it’s important to note that not all medications should be flushed. It is essential to consult the FDA guidelines or your healthcare provider to determine if flushing is appropriate for Brilinta.
  3. Pharmaceutical Disposal Bags: Another option is to use pharmaceutical disposal bags, which are designed specifically for the safe disposal of medications. These bags contain activated charcoal that neutralizes the medications, rendering them safe for disposal in the regular trash. You can find these bags at many pharmacies or online.
  4. Mixing with Unpalatable Substance: You can also dispose of Brilinta by mixing it with an unpalatable substance, such as coffee grounds or kitty litter. This makes the medication less appealing to animals or individuals who may accidentally come into contact with it. After mixing, seal the mixture in a plastic bag and place it in the regular trash.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

Product was successfully added to your cart!