Cambia is a revolutionary pharmaceutical product designed to alleviate pain associated with certain conditions, such as migraines. It is a prescription medication that contains diclofenac potassium, a nonsteroidal anti-inflammatory drug (NSAID). The active ingredient in Cambia works by reducing the substances in the body that cause pain and inflammation.

Cambia is primarily used to treat acute migraines in adults. Migraines can be incredibly debilitating, causing severe headaches, nausea, sensitivity to light and sound, and overall discomfort. Cambia targets the underlying causes of migraines and helps provide relief from these distressing symptoms.

Cambia works by inhibiting the production of certain chemicals in the body known as prostaglandins. Prostaglandins play a role in the body’s inflammatory response, causing pain, swelling, and fever. By blocking the production of these chemicals, Cambia effectively reduces pain and inflammation, providing much-needed relief to individuals suffering from migraines.

Cambia offers numerous benefits to those who use it for migraine relief. Some of the notable advantages include:

  1. Effective Pain Relief: Cambia has been proven to provide effective pain relief for acute migraines, allowing individuals to resume their daily activities without the debilitating effects of severe headaches.
  2. Fast-Acting: One of the key advantages of Cambia is its fast-acting nature. Unlike traditional oral medications, Cambia is available in a powder form that is dissolved in water and consumed. This allows for quicker absorption into the bloodstream, leading to faster relief.
  3. Convenience: The powder form of Cambia makes it convenient to use, especially for individuals experiencing nausea or difficulty swallowing during a migraine attack. Additionally, it eliminates the need for water to swallow pills, making it a practical option for those on the go.
  4. Tailored Dosage: Cambia offers the flexibility of different dosage options, allowing healthcare providers to prescribe the appropriate strength based on the severity of the migraine and individual patient needs.
  5. Reduced Side Effects: As a targeted treatment for migraines, Cambia has been shown to have fewer systemic side effects compared to oral NSAIDs. This makes it a preferred choice for individuals who are sensitive to or have experienced adverse effects with other medications.

Warnings and Precautions

Allergic Reactions

Allergic reactions to Cambia can occur in some individuals. If you experience symptoms such as hives, swelling, difficulty breathing, or a rash after taking Cambia, it is crucial to seek immediate medical attention. Allergic reactions can be severe and potentially life-threatening.

Cardiovascular Risks

Cambia, like other NSAIDs, may increase the risk of cardiovascular events such as heart attack or stroke. This risk may be higher in individuals with pre-existing heart conditions or those who have had cardiovascular events in the past. It is essential to discuss your medical history with your healthcare provider before starting Cambia.

Gastrointestinal Effects

One of the significant side effects of Cambia and other NSAIDs is the potential for gastrointestinal complications. These can range from mild symptoms such as indigestion and stomach upset to more severe issues like stomach ulcers and gastrointestinal bleeding. If you experience persistent abdominal pain, black or bloody stools, or vomit that resembles coffee grounds, seek immediate medical attention.

Kidney Function

Cambia can affect kidney function, especially in individuals with pre-existing kidney problems or those at risk of developing them. It is crucial to inform your healthcare provider if you have a history of kidney disease or if you are taking medications that can affect kidney function. Regular monitoring of kidney function may be necessary while using Cambia.

Side Effects

Cambia is a commonly prescribed medication used to treat pain and inflammation. While it can be effective in providing relief, it’s important to understand the potential side effects that may occur.

Common Side Effects

  1. Headache: One of the most commonly reported side effects of Cambia is a headache. This discomfort usually subsides on its own, but if it persists or worsens, it is advisable to consult your doctor.
  2. Nausea: Some individuals may experience nausea after taking Cambia. This feeling of queasiness can be relieved by taking the medication with food or milk.
  3. Upset Stomach: Cambia can cause an upset stomach, leading to symptoms like indigestion, bloating, and abdominal discomfort. Taking the medication with food can help alleviate these symptoms.
  4. Dizziness: Another common side effect is dizziness. It is important to avoid activities that require mental alertness, such as driving or operating heavy machinery, if you experience dizziness after taking Cambia.
  5. Diarrhea: Cambia may also cause diarrhea in some individuals. Staying hydrated and consuming a balanced diet can help manage this side effect.
  6. Heartburn: Heartburn, characterized by a burning sensation in the chest, is another common side effect. It is recommended to avoid spicy or greasy foods that can exacerbate this symptom.
  7. Rash: In rare cases, Cambia can cause a skin rash. If you notice any unusual skin reactions, discontinue the medication and seek medical attention.
  8. Fatigue: Feeling tired or fatigued is another possible side effect. It is advisable to rest and avoid strenuous activities until the fatigue subsides.
  9. Insomnia: Some individuals may experience difficulty sleeping after taking Cambia. If this side effect persists, consult your doctor for alternative treatment options.
  10. Increased Blood Pressure: Cambia has the potential to increase blood pressure in some individuals. Regular monitoring of blood pressure is essential, especially in those with pre-existing hypertension.

Rare Side Effects

  1. Allergic Reaction: Although rare, some individuals may experience an allergic reaction to Cambia. Symptoms may include hives, itching, swelling, difficulty breathing, and chest tightness. Seek immediate medical attention if you suspect an allergic reaction.
  2. Liver Damage: In rare cases, Cambia can cause liver damage. If you experience symptoms such as yellowing of the skin or eyes, dark urine, or persistent abdominal pain, discontinue the medication and consult your doctor.
  3. Kidney Problems: Cambia may also affect kidney function, leading to symptoms like changes in urination frequency, blood in urine, or swelling in the lower extremities. If you notice any of these symptoms, seek medical advice promptly.
  4. Stomach Ulcers: Long-term use of Cambia can increase the risk of developing stomach ulcers. Contact your healthcare provider if you experience symptoms such as abdominal pain, black stools, or vomiting blood.
  5. Fluid Retention: Cambia can cause fluid retention, resulting in swelling of the hands, feet, or ankles. If this side effect becomes severe or persists, inform your doctor.
  6. Tinnitus: In rare cases, Cambia may cause a ringing sensation in the ears, known as tinnitus. If you experience this symptom, discuss it with your healthcare provider.

Severe Side Effects

  1. Cardiovascular Events: In rare instances, Cambia may increase the risk of cardiovascular events such as heart attack or stroke. This risk is higher in individuals with pre-existing heart conditions or those using high doses of the medication. If you experience chest pain, shortness of breath, or sudden weakness on one side of the body, seek immediate medical attention.
  2. Gastrointestinal Bleeding: Another severe side effect of Cambia is gastrointestinal bleeding. This can manifest as blood in the stool or vomiting blood. If you observe these symptoms, seek urgent medical care.
  3. Stevens-Johnson Syndrome: Although extremely rare, Cambia has been associated with Stevens-Johnson syndrome, a severe skin condition characterized by blistering and peeling of the skin. Discontinue the medication immediately and seek emergency medical treatment if you develop any signs of this syndrome.
  4. Anaphylaxis: Anaphylaxis is a life-threatening allergic reaction that can occur with Cambia. Symptoms may include difficulty breathing, swelling of the face or throat, rapid heartbeat, and dizziness. If you experience these symptoms, call emergency services right away.
  5. Worsening Asthma: Cambia may exacerbate asthma symptoms in individuals with a history of the condition. It is important to monitor your breathing and consult your doctor if you notice any changes in your asthma control.
  6. Vision Changes: Rarely, Cambia may cause visual disturbances such as blurred vision or changes in color perception. If you experience any changes in your vision, consult an eye specialist.

Drug Interactions

While Cambia is generally safe, certain medications, substances, or health conditions may interact with it, warranting caution and appropriate medical advice. Let’s delve into some commonly encountered drug interactions associated with Cambia:

Blood Thinners

Cambia, being an NSAID, may interact with blood thinners such asĀ  Lovenox and Xarelto. These interactions can increase the risk of bleeding. It is essential to inform your healthcare provider about all the medications you are taking, including blood thinners, to ensure appropriate dosing adjustments and monitoring.


Certain antidepressant medications, particularly selective serotonin reuptake inhibitors (such as Viibryd and Cipralex) and serotonin-norepinephrine reuptake inhibitors (SNRIs), may interact with Cambia. This interaction can increase the risk of gastrointestinal bleeding. Patients taking antidepressants should consult their healthcare provider before initiating Cambia to evaluate the potential risks and benefits.


Diuretics, commonly prescribed for conditions such as hypertension or edema, can interact with Cambia. The concurrent use of diuretics and Cambia may reduce the diuretic’s effectiveness, potentially leading to fluid retention. Healthcare providers should monitor patients closely when these medications are used together and consider appropriate dose adjustments.

Angiotensin-Converting Enzyme (ACE) Inhibitors

ACE inhibitors, prescribed for conditions like hypertension and heart failure, may interact with Cambia, diminishing the antihypertensive effects of ACE inhibitors. Healthcare providers should monitor blood pressure levels closely and consider alternative pain management options if necessary.


Cambia has the potential to increase the blood levels of lithium, a medication commonly used to treat bipolar disorder. Patients taking lithium should inform their healthcare provider about their medication regimen before using Cambia to avoid potential adverse effects associated with elevated lithium levels.


Methotrexate, a medication used to treat certain cancers and autoimmune diseases, may interact with Cambia, increasing the risk of methotrexate toxicity. Healthcare providers should closely monitor patients using both medications and consider appropriate dose adjustments or alternative pain management strategies.


To use Cambia effectively, follow the instructions provided by your healthcare provider. Remember to read the medication guide and consult your healthcare provider for specific instructions tailored to your condition. Here are the general steps for using Cambia:

  1. Start by dissolving one packet of Cambia powder in a glass of water.
  2. Stir the mixture well until the powder is completely dissolved.
  3. Drink the solution immediately after mixing.
  4. If needed, you may take a second dose of Cambia after two hours of the first dose. However, it is essential to consult your healthcare provider before taking a second dose.


The typical recommended dose of Cambia for adults is 50 to 100 milligrams (mg) taken at the onset of a migraine headache. The medication is supplied as a powder that you mix with water and drink. It is important to dissolve the powder completely and consume the mixture immediately. If your symptoms persist or worsen after the initial dose, you may take another dose after two hours. However, the total daily dose should not exceed 200 mg.

Missed Dose

If you miss a dose of Cambia, it is important to take it as soon as you remember. However, if it is close to the time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.


Taking more than the prescribed dose of Cambia can lead to an overdose, which may have serious consequences. Symptoms of an overdose may include severe stomach pain, nausea, vomiting, drowsiness, confusion, bleeding, and even kidney or liver problems. If you suspect an overdose or experience any severe symptoms after taking Cambia, it is crucial to seek immediate medical attention or contact your local poison control center.

To ensure your safety and prevent potential drug interactions or complications, it is important to inform your healthcare provider about any other medications, supplements, or medical conditions you may have before starting Cambia. They can provide you with personalized dosing instructions based on your specific needs and medical history.

Remember, the information provided here is a general overview of dosing with Cambia and should not replace the instructions and advice given by your healthcare professional. Always follow their guidance and consult them if you have any concerns or questions about your medication.


Proper storage of Cambia is essential to maintain its effectiveness and ensure its longevity. Proper storage of Cambia is crucial for preserving its quality, potency, and effectiveness. By following these storage guidelines, you can ensure that your supply of Cambia remains in optimal condition for use. In the points below, we will explore the key considerations and best practices for storing Cambia to preserve its quality and potency.

  • Temperature: Storing Cambia at the appropriate temperature is crucial. It is recommended to store this medication at room temperature, typically ranging from 20 to 25 degrees Celsius (68 to 77 degrees Fahrenheit). Avoid exposing Cambia to extreme heat or cold, as it may impact its chemical stability and compromise its effectiveness. Keep the medication away from direct sunlight, heaters, or refrigeration units to maintain its integrity.
  • Moisture and Humidity: Cambia should be kept in a dry environment. Moisture and high humidity levels can lead to the degradation of the medication. To protect it from moisture, ensure that the container or packaging is tightly sealed after each use. Additionally, avoid storing Cambia in areas prone to humidity, such as bathrooms or kitchen cabinets near sinks.
  • Light Exposure: Cambia should be shielded from excessive light exposure. Exposure to light, especially sunlight or ultraviolet (UV) rays, can degrade the medication and reduce its potency. Store Cambia in its original packaging or in an opaque container to prevent direct light exposure. Placing it in a dark cabinet or drawer will help maintain its stability.
  • Proper Packaging: The original packaging of Cambia is designed to protect it from environmental factors that can affect its quality. It is recommended to store Cambia in its original blister packs or tightly sealed containers provided by the manufacturer. These packages are specifically designed to maintain the medication’s stability, protect it from moisture and light, and prevent tampering.
  • Storage Location: Choose an appropriate storage location for Cambia that meets the recommended conditions. Opt for a cool, dry, and dark area away from sources of heat, moisture, and direct sunlight. Avoid storing Cambia in places that experience temperature fluctuations, such as near windows, radiators, or air conditioning vents. Additionally, keep the medication out of reach of children and pets.
  • Avoid Freezing: Cambia should never be frozen. Freezing can alter the chemical composition of the medication, rendering it ineffective. Ensure that Cambia is stored at room temperature and refrain from placing it in the freezer or refrigerator.
  • Checking Expiry Dates: Regularly check the expiration dates of Cambia to ensure its potency. Expired medications may not provide the desired therapeutic effects and could potentially be harmful. Dispose of any expired or unused Cambia properly and consult with your pharmacist or healthcare provider for guidance.


When it comes to disposing of Cambia, it is important to follow specific guidelines to minimize harm to the environment. Here are some effective methods for disposing Cambia responsibly:

Return Unused Medications to Pharmacies

Returning unused medications, including Cambia, to pharmacies is a reliable and convenient method of disposal. Many pharmacies and healthcare facilities have take-back programs where you can drop off expired or unwanted medications. These programs ensure that the medications are disposed of properly, reducing the risk of environmental contamination.

Utilize Medication Disposal Drop Boxes

Medication disposal drop boxes are often available in pharmacies, hospitals, and law enforcement agencies. These secure drop boxes provide a safe and anonymous way to dispose of medications, including Cambia. Simply deposit your unused Cambia in the designated container, ensuring it is properly sealed.

Follow FDA Guidelines for Flushable Medications

While most medications should not be flushed down the toilet or poured down the drain, some exceptions apply. The U.S. Food and Drug Administration (FDA) recommends flushing certain medications, including Cambia, if take-back options are not available. Check the FDA’s list of flushable medications and follow their guidelines to ensure safe disposal.

Mix with Undesirable Substances

Another method of disposing Cambia is by mixing it with undesirable substances such as coffee grounds, cat litter, or dirt. This renders the medication less attractive and less likely to be accidentally consumed by humans or animals. After mixing, seal the mixture in a sturdy container or bag before disposing of it in the regular trash.

Seek Community Disposal Programs

Many communities organize special events or programs for medication disposal. These initiatives aim to raise awareness and provide a convenient way for individuals to dispose of their unused medications, including Cambia. Stay informed about such events in your locality and participate actively to contribute to responsible waste management.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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