Bystolic is a brand-name medication that contains the active ingredient nebivolol. It belongs to a class of drugs called beta-blockers. Nebivolol works by blocking the action of certain natural substances in the body, such as adrenaline, which can increase heart rate and blood pressure. By blocking these substances, Bystolic helps to lower blood pressure and reduce the workload on the heart.

Bystolic is primarily used to treat high blood pressure, a condition that affects millions of people worldwide. High blood pressure can lead to serious health problems, including heart disease, stroke, and kidney damage. Bystolic helps to control blood pressure by relaxing and widening the blood vessels, allowing blood to flow more easily.

Apart from its blood pressure-lowering effects, Bystolic may also be prescribed for other conditions such as heart failure and certain types of irregular heartbeat.


Yes, there are generic versions of Bystolic available. Generic medications contain the same active ingredient as the brand-name drug and work in the same way. They are approved by regulatory authorities to be just as safe and effective as the brand-name medication.

Generic versions of Bystolic are marketed under the name nebivolol and are available at a lower cost compared to the brand-name product. These generics provide an affordable alternative for individuals who need to manage their blood pressure without straining their budget.

MyRx Outlet offers Americans the ability to buy affordable and sage Bystolic generics from the United Kingdom and Mauritius.

Warnings and Precautions

This list of warnings and precautions are not exhaustive, and it is essential to consult your healthcare provider for personalized advice and guidance regarding the use of Bystolic. Your doctor will consider your medical history, current medications, and overall health before prescribing this medication.

  1. Allergic Reactions: Bystolic contains the active ingredient nebivolol, which may cause allergic reactions in some individuals. If you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.
  2. Heart Conditions: Bystolic is primarily used to treat high blood pressure (hypertension) and certain heart conditions. However, it is important to inform your healthcare provider if you have any existing heart problems, such as heart failure, a slow heart rate, or heart rhythm disorders. Bystolic may affect the function of your heart, and your doctor will determine if it is suitable for you.
  3. Asthma and Respiratory Conditions: Bystolic may cause bronchospasm in individuals with asthma or other respiratory conditions. Inform your doctor if you have a history of respiratory problems. They will assess whether Bystolic is appropriate for you or if an alternative medication should be considered.
  4. Diabetes: Bystolic may mask certain symptoms of low blood sugar (hypoglycemia) in individuals with diabetes, such as rapid heartbeat or shakiness. Monitor your blood sugar levels regularly and inform your doctor if you experience any unusual symptoms.
  5. Liver and Kidney Problems: If you have liver or kidney impairment, your doctor may need to adjust the dosage of Bystolic. Inform your healthcare provider about any pre-existing liver or kidney conditions.
  6. Surgery: If you are scheduled for surgery, including dental surgery, inform the surgeon or dentist about your use of Bystolic. The medication may interact with anesthesia or other drugs used during the procedure.
  7. Abrupt Discontinuation: Suddenly stopping Bystolic can lead to a rapid increase in blood pressure or worsening of heart conditions. It is important to follow your doctor’s instructions when discontinuing the medication and to gradually reduce the dosage if necessary.
  8. Driving and Operating Machinery: Bystolic may cause dizziness, fatigue, or blurred vision, which can impair your ability to drive or operate machinery safely. Use caution until you know how this medication affects you.

Side Effects

While Bystolic is generally well-tolerated, it’s important to be aware of both the common and rare side effects that may occur. Understanding the potential side effects of Bystolic can help individuals make informed decisions about their treatment.

Common Side Effects of Bystolic

While Bystolic is generally well-tolerated, some individuals may experience certain side effects during treatment. Common side effects of Bystolic may include:

  1. Fatigue: Some individuals may experience feelings of tiredness or fatigue while taking Bystolic. This side effect is generally mild and tends to improve over time as the body adjusts to the medication.
  2. Headache: Headaches are a common side effect of Bystolic. If you experience persistent or severe headaches while taking Bystolic, it is important to inform your healthcare provider.
  3. Dizziness: Bystolic may cause dizziness, especially when standing up from a sitting or lying position. It is important to get up slowly to minimize the risk of falls or accidents.
  4. Nausea: Some individuals may experience nausea or an upset stomach while taking Bystolic. Taking the medication with food can help reduce these symptoms.
  5. Cold hands and feet: Bystolic may cause a decrease in blood flow to the extremities, resulting in cold hands and feet. Wearing warm clothing and keeping the body warm can help alleviate this side effect.
  6. Insomnia: Bystolic can sometimes interfere with sleep patterns, leading to difficulty falling asleep or staying asleep. If you experience insomnia while taking Bystolic, it is recommended to discuss this with your healthcare provider.
  7. Erectile dysfunction: In some cases, Bystolic may cause sexual problems, such as erectile dysfunction, in men. It is important to communicate any concerns regarding sexual function with your healthcare provider.
  8. Slow heart rate: Bystolic can slow down the heart rate, a condition known as bradycardia. If you experience a significantly slow heart rate or any other concerning symptoms, seek medical attention immediately.

Rare Side Effects of Bystolic

While rare, some individuals may experience less common side effects while taking Bystolic. These side effects may include:

  1. Allergic reactions: In rare cases, Bystolic may cause allergic reactions, such as rash, itching, swelling, or difficulty breathing. If you experience any signs of an allergic reaction, seek immediate medical attention.
  2. Depression: Bystolic may rarely cause or worsen symptoms of depression in some individuals. If you notice any changes in mood or experience feelings of depression while taking Bystolic, it is important to notify your healthcare provider.
  3. Wheezing or difficulty breathing: Bystolic may cause bronchospasm in individuals with a history of asthma or other respiratory conditions. If you experience wheezing or difficulty breathing, seek immediate medical attention.
  4. Unexplained weight gain: Some individuals may experience unexplained weight gain while taking Bystolic. It is important to monitor your weight and inform your healthcare provider if you notice significant weight changes.
  5. Raynaud’s phenomenon: Bystolic may rarely trigger or worsen Raynaud’s phenomenon, a condition characterized by decreased blood flow to the fingers and toes, causing them to turn white or blue. If you experience symptoms of Raynaud’s phenomenon, seek medical advice.
  6. Vision changes: Bystolic may rarely cause vision changes, such as blurred vision or dry eyes. If you experience any changes in your vision while taking Bystolic, consult your healthcare provider.

Drug Interactions

Like any other medication, Bystolic can potentially interact with other drugs, including prescription medications, over-the-counter drugs, and herbal supplements. These interactions can affect the effectiveness of the medications or lead to unwanted side effects. It is important to be aware of these interactions and consult with a healthcare professional before starting or stopping any medications while taking Bystolic.

It is crucial to provide your healthcare provider with a complete list of all medications, including over-the-counter drugs and herbal supplements, that you are taking. This allows them to assess potential interactions and make necessary adjustments to your treatment plan.

Remember, this is not an exhaustive list of all possible drug interactions with Bystolic. Always consult with a healthcare professional or pharmacist for personalized advice regarding your specific medications and health conditions. They can provide guidance on the safe and effective use of Bystolic and help prevent any potential drug interactions.

Here are some common drug interactions associated with Bystolic:

  1. Blood pressure-lowering medications: Bystolic is primarily used to lower blood pressure. If taken with other medications that also lower blood pressure, such as diuretics, ACE inhibitors, angiotensin receptor blockers (such as Diovan and Edarbi), or calcium channel blockers, the combined effect may lead to excessive blood pressure lowering. This can cause dizziness, lightheadedness, fainting, or dangerously low blood pressure. Your doctor may need to adjust the dosages of these medications accordingly.
  2. Medications that affect heart rate: Bystolic can lower heart rate. Therefore, taking it with other medications that also slow down the heart rate, such as beta-blockers, calcium channel blockers, or certain antiarrhythmic drugs, can further decrease heart rate and may result in bradycardia (abnormally slow heart rate). Close monitoring by a healthcare professional is important when using these medications together.
  3. Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, such as Ilevro and Celebrex, are commonly used for pain relief. When taken with Bystolic, they may reduce the blood pressure-lowering effects of Bystolic. It is advisable to use NSAIDs cautiously and only under the guidance of a healthcare professional.
  4. Medications metabolized by CYP2D6: Bystolic is mainly metabolized by an enzyme called CYP2D6 in the liver. Drugs that inhibit or induce this enzyme can affect the metabolism of Bystolic, leading to increased or decreased blood levels of the medication. Examples of medications that may interact include fluoxetine, paroxetine, quinidine, and rifampin. Your doctor may need to adjust the Bystolic dosage if you are taking any of these medications.
  5. Herbal supplements: Certain herbal supplements, such as St. John’s wort, may interact with Bystolic. St. John’s wort can decrease the blood levels of Bystolic, potentially reducing its effectiveness. It is essential to inform your doctor about any herbal supplements you are taking to avoid potential interactions.


Bystolic is available in tablet form and is usually taken once daily, with or without food. The recommended starting dose is 5 mg per day, which may be increased to 10 mg per day based on individual response and tolerability. It is important to take the medication at the same time each day to maintain a consistent level in the bloodstream.

It is crucial to understand the significance of adhering to the prescribed dosage when taking Bystolic. The appropriate dose of Bystolic varies depending on individual factors such as age, medical condition, and response to treatment. Following the recommended dosage guidelines ensures optimal effectiveness of the medication while minimizing the risk of side effects. Always consult your healthcare provider for personalized dosing instructions.

Several factors influence the determination of the appropriate dosage for an individual. These factors include:

  • Medical condition: The severity of your medical condition, such as hypertension, may influence the dosage of Bystolic prescribed by your healthcare provider.
  • Age: Older adults may require different dosages compared to younger individuals due to potential variations in metabolism and other age-related factors.
  • Response to treatment: Your healthcare provider may adjust the dosage of Bystolic based on your body’s response to the medication. Regular monitoring and communication with your healthcare provider are essential for optimizing treatment.
  • Other medications: Certain medications may interact with Bystolic, necessitating dosage adjustments to avoid adverse effects or enhance effectiveness. Always inform your healthcare provider about all the medications you are taking.

Finding the Right Dose: Titration

When initiating Bystolic treatment, your healthcare provider will typically start you on a lower dose and gradually increase it over time. This process, known as titration, allows your body to adjust to the medication and helps find the optimal dose for your condition. Titration also helps minimize the occurrence of potential side effects.


Accidentally taking more than the prescribed dose of Bystolic can be concerning. If you suspect that you have overdosed on Bystolic, it is crucial to take immediate action. Here are the steps you should follow:

  1. Contact emergency services: If you experience severe symptoms or have taken a significantly higher dose of Bystolic, call your local emergency number right away. Inform them about the situation and provide any relevant information they may require.
  2. Seek medical attention: Even if your symptoms are not severe, it is advisable to seek medical attention promptly. Call your healthcare provider or go to the nearest emergency room to discuss your situation and receive appropriate guidance.
  3. Do not induce vomiting: Unless instructed by a healthcare professional, do not try to induce vomiting. Vomiting may not effectively remove the excess medication from your system and can potentially lead to other complications.
  4. Follow medical advice: Cooperate with the medical professionals attending to you. They will evaluate your condition and provide the necessary treatment. It may involve measures to counteract the effects of the overdose and closely monitoring your vital signs.

Missed Dose

Missing a dose of Bystolic is not ideal but can happen to anyone. If you forget to take your regular dose of Bystolic, follow these steps:

  1. Take the missed dose as soon as you remember: If it is still within a few hours of the missed dose, take it as soon as you remember. However, if it is closer to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule.
  2. Do not double the dose: Never take a double dose of Bystolic to make up for the missed dose. Taking a higher dose than prescribed can increase the risk of side effects and complications.
  3. Inform your healthcare provider: It is essential to inform your healthcare provider about the missed dose during your next appointment or through a phone call. They can provide you with guidance on how to proceed and whether any adjustments to your treatment plan are necessary.
  4. Set reminders: To avoid missing future doses, consider using reminders such as alarms or smartphone apps. Setting a routine and taking the medication at the same time each day can also help ensure that you do not forget.


Many expectant mothers may wonder if it is safe to continue taking Bystolic during pregnancy. While there is limited research specifically focused on Bystolic use in pregnant women, some studies suggest potential risks associated with beta-blockers during pregnancy. However, it is crucial to note that every pregnancy is unique, and the decision to continue or discontinue any medication should be made in consultation with your healthcare provider. They will consider the potential risks and benefits based on your specific circumstances.

The following may occur during pregnancy. As mentioned a moment ago, please ensure you have a conversation with your healthcare provider if you are pregnant or plan on being pregnany while taking Bystolic.

  1. Impact on Fetal Growth and Development: Some studies have suggested that beta-blockers, including Bystolic, may affect fetal growth and development. These medications can potentially reduce blood flow to the placenta, leading to restricted growth in the baby.
  2. Neonatal Hypoglycemia: There have been reports of neonatal hypoglycemia (low blood sugar) in infants born to mothers taking beta-blockers during pregnancy. It is important to monitor blood sugar levels in newborns if the mother has been taking Bystolic.
  3. Respiratory Distress: Beta-blockers may cause respiratory issues in newborns, such as difficulty breathing or reduced lung function. Close monitoring of the baby’s respiratory health is essential if the mother has been taking Bystolic.
  4. Hypotension: Bystolic can cause low blood pressure in pregnant women, which may have adverse effects on both the mother and the baby. Your healthcare provider will closely monitor your blood pressure levels throughout your pregnancy.


storage. Proper storage conditions help prevent degradation of the active ingredients, maintain potency, and avoid any potential harm to patients. Here’s what you need to know about storing Bystolic:

Temperature and Environmental Considerations

  1. Ideal Temperature: Bystolic should be stored at room temperature, typically around 68°F to 77°F (20°C to 25°C). Avoid exposing the medication to extreme temperatures, such as excessive heat or cold, as it may affect its effectiveness.
  2. Avoid Moisture: Keep Bystolic away from high humidity areas, such as bathrooms or kitchens. Moisture can lead to degradation of the medication and render it less effective.
  3. Protect from Light: Bystolic should be stored in its original container, which is designed to protect the medication from light exposure. Avoid transferring it to other containers that are not light-resistant.

Storage Locations to Avoid

  1. Avoid Direct Sunlight: Direct sunlight can accelerate the degradation process of Bystolic. Therefore, it is essential to store the medication away from windows or any other areas exposed to direct sunlight.
  2. Steer Clear of Heat Sources: Keep Bystolic away from heat sources like radiators, ovens, or heating vents. High temperatures can negatively impact the medication’s stability and effectiveness.
  3. Stay Away from Freezers: Do not store Bystolic in the freezer. Extreme cold temperatures can cause the medication to lose its potency.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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