Bystolic is an oral drug that is made with the active ingredient Nebivolol. This medication is used for treating high blood pressure, also known as hypertension. Taking this medication causes blood pressure to drop so that the patient has less risk of having a stroke or heart attack. Once you’re taking it, you can’t stop it without talking to your doctor. Stopping it abruptly can cause chest pain in patients as well as a heart attack.

Bystolic is a medication that’s classified as a beta blocker and is further classified as a selective beta blocker. There are chemicals in the body that bind themselves to receptors located in the heart. This medication blocks those chemicals. The result of this is lower blood pressure. This medication also works to relax the blood vessels, and this causes even more lowering of blood pressure.

This drug is often used along with an ACE inhibitor or a diuretic to treat blood pressure that’s anywhere from mildly high to moderately high. When this drug relaxes the blood vessels, it allows blood to go through them more easily, causing blood pressure to lower and reducing the strain on the heart. It also causes the body to make fewer of the chemicals made by the kidneys that cause blood pressure to be high.

Precautions and Warnings with Bystolic 

If you need to stop this medication, get together with your doctor and get a plan for doing so. Never skip doses or stop taking it all at once. The safer plan is to decrease the dosage gradually over a couple of weeks. During this time, you’ll have to limit your activity so that more strain isn’t placed on your heart.  If you get pressure or pain in your chest, start sweating for no reason, have an irregular or fast heartbeat, or you have trouble breathing, get immediate medical help.

You should not take this medication if your heart rate is very slow, or you have sick sinus syndrome. It’s also important not to take it if you’re allergic to it or you have congestive heart failure that’s getting worse. Don’t take this drug if you have liver function that’s severely reduced, have a severe heart block, have liver function that’s seriously reduced, or you have serious disorders of the peripheral arteries. If you have cardiogenic shock or you’re intolerant of glucose, galactose, or lactose, don’t take it, and make sure your doctor knows about your condition.

When you take Bystolic, it can cause impairment of your reactions or thinking. If you need to do anything that requires alertness, such as driving, make sure you know how this medication affects you. When you take this medication, it’s one part of a lifestyle program that includes getting exercise and following a healthy diet. Keep up these lifestyle actions for as long as you’re on this medication. Don’t stop taking it because you feel fine. Many patients have no side effects from their high blood pressure.

It’s possible to develop trouble breathing while on this medication. The risk factors for this are having a history of COPD or asthma. If you have asthma, this medication is not recommended. If you do take this medication, you’ll need close monitoring for breathing problems.

Bystolic can also cause low blood sugar and hide the symptoms of it. If you have a history of diabetes, this is a major risk factor. If you take this and get a lot of sweating, you may have blood sugar that’s too low. Many times, doctors don’t prescribe this medication to diabetics.

If you have hyperthyroidism, this medication can mask the symptoms of having too much thyroid hormone. You’ll likely need regular blood tests, and it’s extremely important not to stop this medication suddenly when you have this condition.

Bystolic Side Effects

Many side effects are possible from this medication. Many patients get no side effects from it, but there are also mild to severe side effects that are possible. If any of these side effects bother you, talk to your doctor. You may need a different medication or a change in your dosage.

Common Side Effects

Some of the most common effects can include:

  • Fatigue
  • Dizziness
  • Cough
  • Dry mouth
  • Back or joint pain
  • Diarrhea
  • Headaches
  • Rash
  • Throat irritation and nasal congestion
  • Vision changes
  • Nausea
  • Trouble sleeping

Rare Side Effects

There are also rarer side effects that can occur, and you’ll need to tell your doctor if you have them. These include:

  • A decreased heart rate
  • Serious dizziness or fainting
  • Difficulty breathing
  • Swelling in the feet or legs
  • Memory trouble
  • Symptoms of heart trouble such as chest pain or an irregular or fast heartbeat

Severe Side Effects

There are also effects that can mean you need immediate medical care. Call 911 or otherwise seek immediate treatment if you have any of the following:

  • Chest pain
  • Symptoms of a heart attack such as chest pain that comes on suddenly, pain that goes to your back, arm, and jaw, vomiting, anxiety, sweating, nausea, and a feeling of the chest being full
  • Symptoms of a severe allergic reaction such as difficulty breathing, cramps in the abdomen, vomiting, nausea, trouble breathing, or face or throat swelling

Drug Interactions with Bystolic

There are a number of drugs, both prescription and over-the-counter, that can cause a bad interaction. Make sure your doctor knows everything you take, even if it isn’t a prescription drug. It’s especially important to tell your doctor if you take:

  • Reserpine
  • Tagamet
  • Digitalis
  • Ticlid
  • Catapres
  • Tapazole
  • Requip
  • Isoniazid
  • Other beta blockers including atenolol, carvedilol, propranolol, labetalol, sotalol, metoprolol, nadolol, etc.
  • Certain antibiotics like terbinafine
  • Certain antidepressants such as Paxil, Zoloft, Prozac, Cymbalta, Norpramin, and Parnate
  • Chloroquine, quinine, or other malaria medications
  • Other medications for the heart or blood pressure such as Verapamil, Amlodipine, Clonidine, Nifedipine, Diltiazem, etc.
  • Drugs for heart rhythm such as Norpace, Rythmol, Quin-G, and Mexitil, etc.
  • Medications for AIDS ir HIV such as ritonavir and delavirdine
  • Certain psychiatric drugs such as Thorazine, Abilify, Haldol, Mellaril, Clozapine, Trilafon, etc.

Strengths and Dosages of Bystolic

This medication is available in tablet form. The strengths available are 2.5 mg, 5 mg, 10 mg, and 20 mg. This medication should be taken at the same time each day and can be taken with food or without. The exact dosage of your prescription will depend on the severity of your condition and how well the medication works for you as well as other factors.

Bystolic tablets:2.5 mg, 5 mg, 10 mg, 20 mg

Cost of Bystolic in America

The cost depends on the specific pharmacy and the strength of your tablets. The 10 mg strength costs about $200 for 30 tablets. You can get this price down by using a free coupon card from a company such as These can be printed at home or picked up in most pharmacies. If you have health insurance, you can generally expect to pay much less than the list price of this medication. You can actually combine a coupon card and your health insurance for a bigger discount.

There is a generic for this medication, so that would normally drop the price of the name brand. However, there is still high demand for this drug, driving the price higher. It’s also a name brand, so this is virtually always higher priced than the generics.

Bystolic Alternatives

There are other blood pressure medications on the market that can be alternatives to Bystolic. These include Norvasc, Losartan, Carvedilol, Hydrochlorothiazide, Atenolol, and Metoprolol.

FAQs of Bystolic

What are the long-term side effects of Bystolic?

Long-term use of this medication can cause long-term side effects like fast mood changes, trouble with thinking clearly or concentrating, memory loss, and disorientation.

How long does Bystolic stay in your system?

It can stay in the body for anywhere from 2.5 days to five days.

Who makes Bystolic?

AbbVie is the maker of this blood pressure drug.

How much does Bystolic lower your heart rate?

During the day, the average is between 116.3+/-13.4 and 97.2+/-14.5. The nighttime average is between 83.6+/-7.1 to 76.3+/-7.14.

What should I avoid while taking Bystolic?

It’s recommended not to drink alcohol while taking it. You should also not take mineral supplements or eat large quantities of fruit, especially bananas.

How fast does Bystolic work?

It can take as long as four hours for it to work.

What class of drug is Bystolic?

It’s classified as a beta-blocker.

What does Bystolic do for calcium levels?

It does not greatly affect calcium levels, as it is a beta-blocker rather than a calcium channel blocker.

When is the best time to take Bystolic?

It can be taken at any time of day, but it should be taken at the same time every day.

What happens if I have taken too much Bystolic?

Taking too much of it can cause you to have blood pressure that’s dangerously low, low blood sugar, vomiting, and dizziness. If you take too much, you can call Poison Control or get emergency medical help.

What happens if I miss a dose of Bystolic?

After missing a dose, be sure to take it as quickly as you can. However, if it’s close to time for your next dose, wait until it’s time for that dose and take the regular dose. Never take two Bystolic doses close to each other.

Is there a proper way to stop taking Bystolic?

Yes, you need to work with your doctor to taper off this medication slowly. Stopping it suddenly can cause severe reactions.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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