Aggrastat is a medication that uses the active ingredient tirofiban hydrochloride. It’s an anti-platelet medication that prevents the platelets in the blood from clotting or coagulating. It can be used to keep blood clots from forming and can prevent heart attacks when people have a condition such as severe chest pains. It’s also for patients who are getting an angioplasty to open arteries that have become blocked. It’s a highly effective medication that works fast to prevent ischemic events.

Aggrastat  Precautions and Warnings

It’s essential not to take this drug if you’ve ever had an allergic reaction to it. You also shouldn’t use it if you currently have any internal bleeding. This includes bleeding in areas like the intestines and stomach as well as elsewhere. If you have any history of having a blood clotting or bleeding disorder, you shouldn’t take this medication.

If you’ve ever been treated with tirofiban and had low blood platelets, your doctor will likely not prescribe this. If you’ve had an injury, any surgeries, or a medical emergency that occurred in the last 30 days, you shouldn’t take this medication. Be sure to inform your doctor if you’ve ever had kidney disease.

If you’re pregnant, make sure your doctor knows about it. This is especially true if you’re taking aspirin while pregnant. Don’t breastfeed while taking this medication.

The most common complication that can come with this medication is bleeding. Most of the time, it happens during cardiac catheterization at the site of arterial access. Using certain medicines along with this one can give you a higher chance of bleeding.

Another complication that can happen is that the patient develops thrombocytopenia. This is a condition where the platelets get too low in number. This can cause bleeding problems. If a patient develops this condition, they must discontinue this medication.

Ensure your doctor knows everything you’re taking, even if it’s over the counter. They will need to understand your complete health history before prescribing this medication. Don’t do any activities that put you at a high risk of injury, such as playing a contact sport or hiking through thick brush. Take special care when you shave and brush your teeth. You may need to avoid flossing until after you finish this medication.

Side Effects of Aggrastat

Many side effects can occur when you’re taking this medication. Several common side effects and more severe side effects can cause significant problems. The serious side effects should be reported to your doctor right away.

If you have swelling of your lips, face, throat, or tongue, trouble breathing, or hives, these are signs of a severe allergic reaction. This necessitates getting immediate medical care. If you suddenly have vision problems, blurry vision, or swelling of the eyes, you also need to seek emergency care. If you have severe heart symptoms like chest fluttering, shortness of breath, or passing out, you need emergency medical care. You may also need it for confusion, an intense headache, stiff muscles, or tremors.

Various areas may bleed when you take this medication. Ensure your doctor knows you’re having bleeding as soon as it starts. When the bleeding gets severe, it can be life-threatening. You could have bleeding on the outside of the body, or it could be inside. Tarry or bloody stools, coughing up blood, and vomiting a substance that appears like coffee grounds are all signs that you could have internal bleeding located in your digestive tract.

Common Side Effects

  • Stomach pain
  • Sore throat
  • Nausea
  • Headache
  • Stuffy or runny nose
  • Dizziness
  • Cough
  • Water retention
  • Excessive sweat
  • Blood in the urine
  • Pelvic pain
  • Slow heart rate
  • Leg pain

Serious Side Effects

  • Difficulty breathing
  • Bleeding that won’t stop
  • Hives
  • Bleeding or bruising easily
  • Bleeding in the area around the catheter or IV
  • Tarry or bloody stools
  • Vomiting that resembles coffee grounds
  • Coughing up blood
  • Nosebleeds that won’t stop
  • Chest pain
  • Sudden weakness or numbness
  • Sweating, nausea, and pain that’s in the shoulder or arm
  • Bloody, black, or tarry stools
  • Flu-like symptoms

Aggrastat Drug Interactions

There are a lot of drugs that shouldn’t be used with Aggrastat. There are still others that would require a lot of monitoring if you take them with Aggrastat. Ask your doctor before you take any NSAIDs like Celebrex, aspirin, meloxicam, naproxen, ibuprofen, diclofenac (found in Voltaren), and more.  Taking an NSAID along with Aggrastat can lead you to bleed or bruise more easily.

Several substances can cause mild interactions with Aggrastat. These include verteporfin and levothyroxine (found in Synthroid). It also contains herbs, spices, and supplements like horse chestnut seed, ginger, devil’s claw, and ginkgo biloba.

Several medications and supplements can be used with Aggrastat with close monitoring. These include betrixaban, acalabrutinib, dabigatran (found in Pradaxa), defibrotide, deferasirox, and many more.

Avoid drinking alcohol while you take this medication. If you drink while taking it, it can raise the risk of bleeding in the intestines or stomach.

Avoid taking these medications while you’re on Aggrastat:

  • Abrocitinib
  • Apixaban (Eliquis)
  • Antithrombin alfa
  • Aspirin rectal
  • Argatroban
  • Caplacizumab
  • Bivalirudin
  • Antithrombin III
  • Dalteparin (Fragmin)
  • Protamine
  • Enoxaparin (Lovenox)
  • Heparin
  • Fondaparinux (Arixtra)

FAQs of Aggrastat

Can you drink alcohol with this medication?

No, it’s important not to drink alcohol while you’re taking Aggrastat.

Can you take this medication while you’re pregnant?

Whether you take this during pregnancy depends on your doctor. There are a lot of unknowns when it comes to this medication and pregnancy. If the drug is needed, it might be prescribed for a pregnant woman. It would be best if you didn’t breastfeed while you were taking it.

Can you take OTC pain relievers with this medication?

No, this shouldn’t be done. NSAIDs can make it more likely that you’ll bleed or bruise more efficiently, and this can be dangerous.

Are there side effects when you take Aggrastat?

Yes, there can be several possible side effects. People get many milder side effects, such as nausea, cough, headache, and water retention, as well as many others.

Can I take herbs and other supplements with this medication?

Several spices, herbs, and supplements shouldn’t be taken with this medication. Be sure to ask your doctor before taking anything, even if it’s over the counter while taking Aggrastat. Some may result in severe side effects.

What are the chances that I’ll have bleeding from this medication?

This is the most common side effect. About 11% of patients develop some bleeding, even minor. Be sure not to take anything that could make bleeding worse, such as NSAIDs and certain medications. Don’t take a lot of chances while on this medication. Doing dangerous activities can lead to excessive bleeding.

What does this medication treat?

Aggrastat is given to patients who have severe chest pains to help prevent them from having a heart attack. It is also used when a patient needs an angioplasty for blocked arteries.

Are there any prescription drugs that can interact badly with this medication?

Yes, many of them can have harmful interactions. Make sure you tell your doctor everything you’re taking. This includes anything over the counter.

Are there any foods I need to avoid while taking Aggrastat?

Yes, there are a few items to avoid, such as ginger and horse chestnut seeds. Also, avoid alcohol.

How is this medication administered?

It comes in IV solutions only. There is no oral form of Aggrastat.

Can patients be allergic to this medication?

Yes, it’s rare to have a severe reaction to it, but it can happen. If you have an allergic reaction, you may experience a rash, trouble breathing, hives, itching, and swelling or itching in your mouth or face.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

Product was successfully added to your cart!