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Terconazole cream is a medication used to treat vaginal yeast infections by inhibiting the growth of the fungus candida. It belongs to the class of antifungal medications known as azoles and is applied directly to the vaginal area.
Terconazole cream works by targeting the cell membrane of fungi, specifically those causing vaginal yeast infections. It inhibits the enzyme lanosterol 14α-demethylase, which helps in the synthesis of ergosterol— a critical component of fungal cell membranes.
With inadequate ergosterol, the cell membrane becomes destabilized and permeable. This disruption allows essential cellular contents to leak out and harmful substances to enter the cell, ultimately leading to the death of the fungal cell.
Labeled Warning For Terconazole Cream
Never use Terconazole cream orally. It should only be used in the vagina.
Do not stop using Terconazole cream after symptoms improve. Complete the prescribed dosage to prevent the risk of having an infection that is resistant to this medication.
Avoid using tampons while taking Terconazole because tampons can absorb the medication, rendering it less effective.
Avoid intercourse while under medication because sexual intercourse can interfere with the proper functioning of the drug. Terconazole could be displaced during intercourse hindering its effectiveness in treating the infection.
Terconazole Cream Precautions
- Pregnancy: Tell your doctor if you are pregnant or intend to get pregnant because Terconazole may harm the developing fetus.
- Allergic Reactions: Terconazole cream may cause a serious allergic reaction called anaphylaxis. Inform your doctor if you’re allergic to the medication or any of its ingredients.
- HIV/AIDS: If you’re suffering from HIV/AIDS, inform your doctor before using Terconazole cream because it may interact with HIV/AIDS medication and cause severe side effects or prevent it from being effective.
- Photosensitivity: Do not prolong treatment since long-term usage of the medication will result in photosensitive skin becoming very sensitive to sunlight leading to skin reactions or sunburn.
Terconazole Cream Side Effects
Using Terconazole can result in side effects as your body gets accustomed to the medication. Mild reactions are more common while severe reactions are infrequent but would require medical intervention.
Common Side Effects
- Chills
- Difficult urinating
- Itching
- Fever
- Runny nose
- Vomiting
- Shivering
- Stomach pain
- Cramps
- Headache
Severe Side Effects
- Fast heartbeat
- Weakness or unusual tiredness
- Muscle or joint pain
- Trouble breathing
- Dyspnea
- Vaginal pain
- Allergic reactions such as swelling of your face and limbs
- Body pain
- Burning sensation in the vagina and irritation or itching
- Skin reactions such as hives and rashes
Drug Interactions With Terconazole Cream
Terconazole can interact with a variety of other drugs, potentially altering their efficacy or intensifying side effects. Some common drug interactions with Terconazole cream include:
| Drug | Interaction |
| Rifampin | Rifampin can decrease the effectiveness of Terconazole cream by inducing liver enzymes causing side effects such as reduced antifungal efficacy, liver toxicity, and rash. |
| Estrogens oral contraceptives | Terconazole may affect estrogen levels potentially reducing the efficacy of birth control. This may lead to unintended pregnancy, nausea, and breakthrough bleeding. |
| Cyclosporine | Terconazole may affect the metabolism of Cyclosporine increasing its concentration in blood and leading to kidney damage or increased blood pressure. |
| Ritonavir | Ritonavir may affect the metabolism of Terconazole which may alter antifungal efficacy, increase side effects, and gastrointestinal issues. |
| Warfarin | Terconazole may increase the effects of warfarin, leading to a higher risk of excessive bleeding, bruising, and potential for dangerous bleeding complications. |
| Fluconazole | Increases the risk of systemic side effects such as nausea, headache, dizziness, liver enzyme changes, and the potential for severe allergic reactions. |
| Prednisone | Prednisone may suppress the immune response, potentially affecting the efficacy of Terconazole and increasing the susceptibility to infections, gastrointestinal issues, and mood changes |
Strengths and Dosages of Terconazole Cream
Since Terconazole cream may leak during the day, it is best to apply it before going to bed. Do not use Tampons while receiving treatment.
Even if your symptoms become better during the course of treatment, keep taking the medication for the whole recommended amount of time. If your monthly cycle starts while you’re still using the cream, don’t discontinue the medication.
| Age | Strength | No. of times per day |
| Adult | 5mg | Once per day |
Alternatives of Terconazole Cream
When managing vaginal infections, doctors can recommend a variety of antifungal treatments besides Terconazole cream. Treatment can vary from creams, suppositories, and oral tablets. The choice of medication will depend on the patient’s health profile, personal preference, and more. Some alternatives of Terconazole include:
- Fluconazole
- Monistat
- Gyne-Lotrimin
- Diflucan
- Nystop
- Lamisil
- Lotrimin
- Clotrimazole
- Nystatin
- Miconazole
- Sporanox
- Zeasorb
Terconazole Cream FAQs
What is Terconazole cream?
Terconazole cream is an antifungal medication used to treat vaginal yeast or fungal infection.
How does Terconazole cream work?
Terconazole cream works by targeting fungal cells. It interferes with the cell membrane of the fungi hence preventing it from producing components responsible for their survival and therefore causing its death.
How long does it take for Terconazole cream to be effective?
It takes approximately 5 to 10 hours for the medication to work effectively after being inserted into the vagina.
Can I pee after inserting the Terconazole cream?
Yes. You can pee comfortably after inserting the Terconazole cream.
What are the side effects of Terconazole cream?
You may experience side effects like cramps, fever, stomach pain, allergic reactions, blistering, dizziness, irregular heartbeat, and diarrhea after using Terconazole cream.
How long does Terconazole cream stay in your system?
Terconazole cream typically stays in your system for up to 16 hours after the last dose.
What happens If I miss a dose of Terconazole?
Apply Terconazole as soon as you remember. If your next dose is close, skip the missing dose and proceed with the usual dosage.
Which one is better, Terconazole or Monistat?
The decision between Terconazole and Monistat is based on a number of unique criteria, including the particular strain of yeast, the patient’s reaction to the drug, and any adverse effects. For vaginal yeast infections, both medications work effectively.
Can I use Terconazole while on my period?
Yes. You can use Terconazole during your period. Continue the treatment as prescribed without interruption.
Who should not use Terconazole cream?
You should not use Terconazole cream without consulting a doctor if you’re allergic to the cream, have a serious liver illness, or are pregnant. Also, do not combine Terconazole with other vaginal drugs without first talking to a physician.
Our Guarantee For Buying Terconazole Cream From A Canadian Pharmacy Partner
At MyRx Outlet, we are committed to delivering safe, high-quality medications that you can trust. We adhere to strict regulations in every country we operate in, ensuring that your order is handled by a licensed Canadian pharmacy or a trusted partner overseas. Each medication has been legally approved by Health Canada or other respected authorities. To purchase Terconazole Cream at a discounted rate, call 1-888-551-2467.
IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.
