Oxiconazole nitrate cream is a topical anti-fungal cream that treats common skin infections caused by fungi. Fungi are microorganisms like yeasts and molds often found in warm, damp environments. They can colonize parts of the human body, like skin folds and creases. These fungi also thrive in wet or sweaty garments like socks and underwear. Oxiconazole nitrate treats fungal infections by keeping fungus from spreading.

Ringworm is a fungal infection with a distinctive round shape. Infected areas typically have a round, ring-like border. The skin inside may be clear, but irritated bumps may also be present. Ringworm is typically itchy. Despite its name, ringworm is caused by fungus and not by worms. Oxiconazole nitrate cream is a standard treatment for ringworm across the body.

Oxiconazole nitrate cream is a topical cream that attacks the integrity of fungal cells. In particular, oxiconazole prevents fungal cells from making ergosterol, a waxy material in fungi cell walls. Fungal cell walls lose strength and structure without ergosterol. Eventually, the walls weaken so much that the cell bursts and dies. This fights fungal infections by killing the pre-existing fungal cells and preventing them from reproducing.

Oxiconazole nitrate is sold as a generic and under the brand name Oxistat. This medicine is only available with a prescription, although other anti-fungal treatments are sold over the counter. Oxiconazole nitrate is typically prescribed to treat ringworm, including:

  • Tinea corporis, ringworm of the body
  • Tinea pedis, ringworm of the foot (athlete’s foot)
  • Tinea cruris, ringworm of the groin (jock itch)
  • Tinta versicolor, ringworm of the trunk

Precautions and Warnings About Oxistat

Oxiconazole nitrate cream is a standard treatment for ringworm and other skin infections because it’s effective and generally well-tolerated. However, patients should still follow basic precautions and warnings while using oxiconazole nitrate.

Don’t use oxiconazole nitrate cream or inactive ingredients if you’re allergic to it. Ask your doctor if oxiconazole nitrate cream is safe to use if you’re allergic to other medicines in the azole anti-fungal class.

Oxiconazole nitrate will help clear up an infection, but you may need to make lifestyle changes to keep the infection from returning. Ringworm thrives in warm, damp environments. Ringworm variants like jock itch and athlete’s foot are associated with sweat, sports gear, and tight-fitting clothes where fungi thrive. Take the following steps to reduce your risk of infection:

  • Change out of damp or sweaty clothes, socks, and equipment as soon as possible
  • Choose socks and underwear made of natural fibers like cotton
  • Avoid tight-fitting underwear
  • Change socks when they get sweaty
  • Bathe regularly, including after exercising
  • Dry thoroughly, including between toes and in skin creases
  • Wear sandals or shoes that allow ventilation when possible
  • Use absorbent powder on the skin, in socks and shoes, and on equipment that touches the skin
  • Regularly clean locker rooms, bags, uniforms, clothing, and athletic equipment

Oxistat Side Effects

Oxiconazole nitrate cream is a topical medicine, so most of its side effects are also topical. These include irritation on the application side, such as temporary burning or itching. The initial ringworm infection may already be irritated, so applying oxiconazole nitrate may make it feel worse. Tell your doctor if this symptom gets more severe over time or disappears.

Rarely do some patients have an allergic reaction to oxiconazole nitrate cream. Signs of an allergic reaction include hives, redness or swelling, difficulty breathing or swallowing, and elevated heart rate. Get medical attention if you have any symptoms or new skin irritation in places where you didn’t apply the medicine.

Oxistat Drug Interactions

Oxiconazole nitrate cream rarely interacts with other medications. Since it is a topical medicine applied to the skin, it shouldn’t interfere with oral medications metabolized in the digestive tract. However, interactions are still possible. Tell your doctor about your medications before starting oxiconazole nitrate cream.

You should also discuss over-the-counter skin care products like lotion, sunscreen, and acne treatments that you use. Combining other products with oxiconazole nitrate could cause skin irritation or other side effects.

Strengths and Dosages of Oxistat

Oxiconazole nitrate cream is available as a 1% cream in 30g, 60g, and 90g tubes. The typical dosing schedule varies based on the type of infection being treated.

Infection Being Treated Application Instructions Length of Treatment
Tinea corporis (ringworm of the body) Once or twice daily to affected areas and surrounding areas Two weeks
Tinea cruris (jock itch) Once or twice daily to affected areas and surrounding areas Two weeks
Tinea predis (athlete’s foot) Once or twice daily to affected areas and surrounding areas One month
Tinea versicolor (ringworm of the trunk) Once daily Two weeks

Alternatives to Oxistat

Yes, there are other ways to treat ringworm besides oxiconazole nitrate cream, such as:

  • Alevazol
  • Diflucan
  • Extina
  • Gynazole-1
  • Jublia
  • Luliconazole
  • Micatin
  • Miconazole
  • Mycelex
  • Noxafil
  • Spectazole
  • Sporanox
  • Terazol 3
  • Vfend
  • Vusion
  • Zeasorb

Oxistat FAQs

Why was I prescribed oxiconazole nitrate cream?

This medicine is an anti-fungal that treats ringworm infections on your skin. These infections include jock itch, athlete’s foot, and tinea versicolor. Your doctor prescribed oxiconazole nitrate cream to fight this infection.

How long do I need to use oxiconazole nitrate cream?

Take this medicine as directed, even after you start to feel better. Fungal infections can grow from just a few cells. It’s essential to take oxiconazole long enough to wipe out the entire infection so it doesn’t return.

How else can I fight jock itch or athlete’s foot?

Keep yourself as clean and dry as possible to prevent fungal infections. Try to change out of your workout gear as soon as possible; dry off thoroughly after showers; wear cotton socks and underwear; and clean your workout equipment after use.

Does oxiconazole nitrate cream treat other infections besides ringworm?

It would be best if you only used oxiconazole nitrate cream to treat ringworm. Please don’t use it for other infections unless your doctor prescribes it. Oxiconazole nitrate cream is only for topical use. Please don’t use it on your eyes or eat or swallow it. You also shouldn’t use it on mucus membranes, such as vaginally or inside your nose.

What is the Cost of Oxistat in America?

The generic version of oxiconazole nitrate cream costs around $500 for a 30g tube. This price is before discounts or insurance benefits. If your insurance covers oxiconazole nitrate or if you have a coupon, the cost may be closer to $150.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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