Domperidone is a prokinetic and antiemetic medication designed to treat nausea, stomach pain, and vomiting. Sometimes, the nausea and vomiting come as a result of medicine used to combat Parkinson’s disease. This oral tablet can also be prescribed to increase a woman’s supply of milk when she’s breastfeeding.

Domperidone works by increasing stomach/intestine movements and muscle contractions. With more movements and contractions in the stomach and/or intestines, food has a much smoother transition through the digestive tract, thus relieving pain and discomfort. This medication can also cut off the gut’s dopamine receptors.

When prescribed to increase a woman’s breast milk supply, Domperidone generates higher levels of prolactin. This is a hormone that boosts breast milk production and leads to a higher, faster supply of it within a woman’s body.

Precautions and Warnings with Domperidone

The FDA does not recommend Domperidone and warns that taking it can lead to irregular heartbeats. The FDA has not approved Domperidone in the United States and MyRx does not sell Domperidone online to any of its customers.

Before taking Domperidone , let your doctor know about any allergies you have to animals, foods, preservatives, or dyes. This medication is not confirmed as safe for children younger than 12 years old. You should not take domperidone if you are allergic to it or any of its ingredients.

Studies have not yet determined whether Domperidone poses a risk to infants drinking breast milk. You should consult your doctor before using this medication to increase your supply of breast milk.

You should inform your doctor about your medical history before starting Domperidone . This medication may not be safe for you to take if you have a history of the following:

  • Intestinal blocks or tears
  • Kidney or liver issues
  • Heart problems
  • Stomach bleeding
  • Recent abdominal surgery
  • Body weight under 77 pounds
  • Prolactinoma
  • Achlorhydria

Domperidone Side Effects

Domperidone impacts your stomach’s functions (and breast milk supply for women) and may lead to a series of various side effects.

Mild Side Effects

If you start to experience mild side effects after starting Domperidone , they may disappear with time as your body gets used to the medication. If the following side effects persist, be sure to inform your doctor:

  • Dry mouth
  • Hot flashes
  • Itchy skin
  • Breast pain
  • Breast milk leakages
  • Eye pain
  • Headache
  • Menstrual changes

Sexual Side Effects

Domperidone can lead to the following sexual side effects. Contact your doctor if these side effects persist:

  • Lower libido in males
  • Sudden changes in urination

Severe Side Effects

If you begin to experience severe side effects after you start Domperidone , tell your doctor right away. If you feel you’re having a medical emergency, contact 911 immediately. Severe side effects from Domperidone are not usual.

Severe side effects from Domperidone can include the following:

  • Speaking problems
  • Irregular heartbeat
  • Fainting
  • Lightheadedness
  • Loss of muscle control and/or balance
  • Dizziness

Drug Interactions With Domperidone

Before you get on Domperidone , you should let your doctor know about any herbs, vitamins, supplements, or over-the-counter medicines that you’re taking or planning to take.

Domperidone may interact with other medications. You should let your doctor know if you’re taking prescription drugs to treat any of the following issues:

Strengths and Dosages of Domperidone

Domperidone is available in doses of 10 mg to 20 mg. Individual doses may vary according to the ailment that needs treatment.

To treat vomiting and nausea, adults are typically prescribed 20 mg of Domperidone to be taken three to four times every day. For intestinal problems, adults may be prescribed 10 mg or 20 mg of Domperidone for consumption three to four times each day.

To increase a woman’s supply of breast milk, she may be prescribed 10 mg to take every eight hours.

Domperidone should not be taken at higher levels than prescribed. This can lead to extreme side effects. You should not chew, split, break, or brush domperidone as this may impact its effectiveness.

If you miss a dose of Domperidone , take it as soon as you remember. If it’s just about time for your next dose, forget the missed dose and take the next scheduled one. If you believe you’re facing life-threatening health problems, call 911 right away.

Domperidone Alternatives

Metoclopramide has been cited as an alternative to Domperidone and carries far fewer cardiovascular risks. It is an FDA-approved dopamine receptor agonist used to help people experiencing vomiting, nausea, or other stomach problems.

FAQs of Domperidone

What is Domperidone?

Domperidone is a prokinetic and antiemetic medication designed to help people facing nausea, stomach pain, vomiting, or low breast milk supply.

Does Domperidone increase break milk?

Domperidone can increase breast milk by creating higher levels of the hormone prolactin.

Do people use Domperidone for breastfeeding?

Domperidone has been used in non-US countries for breastfeeding.

How long does Domperidone stay in your system?

Domperidone generally remains in the human body for seven to nine hours.

How much Domperidone to take for lactation?

For lactation, 10 mg of domperidone is typically prescribed.

How long does it take for Domperidone to leave your system?

Domperidone generally leaves the human body after seven to nine hours.

When is the best time to take Domperidone?

Domperidone should be taken 15 to 30 minutes before eating a meal or snack.

What foods should you avoid while taking Domperidone?

You should avoid grapefruit (and grapefruit juice) while taking Domperidone .

Can you drink alcohol while taking Domperidone?

You should not drink alcohol while taking Domperidone .

How long does Domperidone withdrawal last?

In breastfeeding women, Domperidone withdrawal can last for up to eight weeks.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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