Dalacin Vaginal Cream is an effective antibiotic option for bacterial vaginosis. It works by reducing infection-causing bacteria through disrupted protein production.

When used as directed for seven days, it resolves vaginal symptoms with side effects like irritation, which are generally mild. For better therapeutic results, you should discuss your circumstances with your healthcare provider.

Clindamycin inhibits bacterial protein synthesis, hence halting the growth of infection-causing bacteria. The cream is typically prescribed as a once-daily, bedtime application for 3-7 days, depending on the severity of the infection.

How Does Dalacin Work?

Dalacin Vaginal Cream contains an antibiotic called Clindamycin (the same active ingredient is found in medications such as Onexton and Benzaclin). This antibiotic obstructs bacteria from synthesizing the proteins needed to grow and multiply.

As a result, the bacteria dies off due to a deficiency of these essential proteins, letting the body’s natural defenses clear up the infection.

Precautions and Warnings of Dalacin


Several considerations should be made before using Dalacin Vaginal Cream to ensure safe use of the drug.

  • Allergies: Data from the Drug and Health Product Portal suggests that those with allergies or reactions to clindamycin, lincomycin, or ingredients in the cream should avoid using it.
  • History of colitis, Crohn’s disease, or antibiotic-associated diarrhea: Use it cautiously, as clindamycin may exacerbate these conditions.
  • Pregnant or Breastfeeding Women: The effects on the fetus or infant are unknown. Never use unless under strict medical supervision.
  • Kidney Dysfunction: Clindamycin may increase systemic absorption.


Further, several warnings are present during use of the cream, including:

  • Seek medical help if severe, bloody, or persistent diarrhea develops, indicating possible antibiotic-associated colitis.
  • Refrain from vaginal intercourse while using the cream due to potential weakening of condoms, diaphragms, and other latex products by the cream.
  • Don’t use other vaginal products like douches or tampons while using Dalacin
  • Make sure you are not menstruating when using this drug. Use when your periods are finished.
  • Avoid direct contact with your eyes. Rinse thoroughly in case of contact.

Side Effects of Dalacin?

Like most medications, Dalacin Vaginal Cream may cause some unintended side effects along with its desired therapeutic effects.

Common Side Effects

These effects tend to be mild and often resolve with continued use.

The side effects below may vary between patients depending on age, gender, or medical history. Patients must alert their healthcare provider if any worrisome symptoms develop. This way, you can provide prompt evaluation and intervention if appropriate.

Some common side effects reported include:

  • Abdominal discomfort
  • Diarrhea
  • Dizziness
  • Headaches
  • Heartburn
  • Vaginal itching
  • Nausea or vomiting.

Serious Side Effects

A few severe side effects may also occur while using Dalacin, including:

  • Burning
  • Itching
  • Rashes
  • Pain on urination
  • Unusual vaginal discharge.
  • Signs of allergic reaction – rash, hives, facial swelling, breathing difficulties
  • Symptoms of colitis – severe abdominal pain, bloody/watery diarrhea

Drug Interactions With Dalacin

When taking any medication, you must be aware of any potential drug interactions. These occur when a drug affects the activity of another drug taken at the same time.

ErythromycinIt may reduce clindamycin effectiveness or increase side effectsAvoid taking them together unless directed by a physician
Neuromuscular blockersIt may increase muscle relaxant effectsInform the physician if taking any muscle relaxants before using Dalacin
Hormonal contraceptivesMay reduce birth control effectivenessUse additional contraceptive methods while taking Dalacin

To minimize risks, patients should inform all healthcare providers about any medications, herbs, or supplements they use. With this complete information, physicians can guide on safely using Dalacin Vaginal Cream with other substances to avoid reduced efficacy or unintended effects.

Furthermore, patients should follow doctors’ directions closely and report any problematic symptoms immediately. Diligence regarding drug interactions helps optimize treatment outcomes.

Strengths and Dosages of Dalacin

Dalacin Vaginal Cream is available as a 2% topical preparation, with each pre-filled applicator delivering approximately 100 mg of the active ingredient clindamycin phosphate.

The standard prescription regimen is one full applicator (5 grams) inserted intravaginally at bedtime for seven consecutive nights. Studies indicate that a shorter 3-day course may also be practical, depending on the severity of infection.

Dalacin is not recommended in pediatric populations or populations older than 60. Additionally, treatment should be avoided during menstruation, with application advisable only after menstrual flow ceases.

You should note that Dalacin Vaginal Cream contains mineral oil as an inactive ingredient. This can weaken latex rubber products such as condoms or contraceptive diaphragms. As such, patients must use alternate contraceptive precautions if engaging in sex while utilizing this medicated cream.

Following the prescribed 7-day regimen at the proper 2% strength allows optimal resolution of Bacterial Vaginosis while considering specific dosing principles and warnings.

Alternatives of Dalacin

The table below compares Dalacin costs to alternative products commonly used to treat vaginal infections:

Alternative NamesStrengthsCostsAvailability of Generics or Similar Treatments
Dalacin Vaginal Cream2% clindamycin phosphate$1.18 – $2.50 per gramss, generic available
Zidoval0.75% metronidazole gel$0.67 – $1.00 per gramYes, generic available
Metronidazole oral tablets250mg or 500mg metronidazole$0.06 – $0.30 per tabletYes, generic available
Replens Long-Lasting Vaginal MoisturizerPolycarbophil-based bioadhesive$0.67 – $0.83 per applicationOTC product, no prescription needed
AH! YES VM Vaginal Moisturizing GelOrganic aloe vera and flax extract$0.50 – $0.67 per applicationOTC product, no prescription needed

There are generic formulations of Dalacin and specific alternative topical treatments available. Patients are advised to consult their doctor and pharmacist to choose the most suitable option based on their needs and budget.

FAQs of Dalacin

What is Dalacin Vaginal Cream used for?

Dalacin is a prescription cream that treats vaginal infections caused by specific bacteria. The antibiotic ingredient in Dalacin works by stopping the growth of bacteria responsible for the infection.

How long does it take for Dalacin Vaginal Cream to work?

The standard treatment course is one applicatorful (5 grams) of Dalacin cream inserted in the vagina every night at bedtime for seven nights in a row. However, a 3-day application may also be practical. A fully prescribed treatment is vital to completely eliminating the infection bacteria.

Can Dalacin Vaginal Cream affect birth control?

Yes. Dalacin cream contains mineral oil that may weaken certain contraceptives, like condoms or vaginal diaphragms. So, alternative birth control should be used during Dalacin treatment.

Is Dalacin Vaginal Cream available over the counter?

No, Dalacin is a prescription medication that requires approval from a doctor before use. It is only sold over the counter with a prescription.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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