Jublia is a prescription drug used to treat stubborn fungal nail infections. Also called onychomycosis, this fungal infection causes the fingernails and toenails to become yellow, brittle, and painful.

Jublia, an effective topical medication, penetrates through the nail and addresses onychomycosis effectively and conveniently. As a result, Jublia has become popular for nail and beauty.

Like many medications in the United States, Jublia is usually not covered by health insurance. This has become a popular medication to buy online from Canada from prescription fulfillment services like MyRx Outlet.

How Does Jublia Work?

It is essential to note that Jublia works in a precise and confined manner. It reduces systemic side effects of oral antifungals by targeting nail fungus cells. You should also remember that Jublia’s success requires persistent and proper use. For best results, it is recommended that you adhere to your doctor’s prescription and keep your nails clean.

While Jublia is a fungal treatment, particularly working against Trichophyton rubrum and Trichophyton mentagrophytes nail infections, it may not work for all fungal diseases. If you are looking forward to an accurate diagnosis and customized treatment, it will be best if you visit your doctor.

Understanding how Jublia fights fungal nail infections chemically can explain its efficacy and why it’s unique among antifungals. Here’s how Jublia works to provide satisfactory results:

  • Slows Ergosterol Synthesis: Ergosterol is a molecule that maintains the structural strength of fungal cell membranes. Jublia’s key ingredient, Efinaconazole, specifically targets this molecule when fighting fungal toe infection. Efinaconazole destabilizes fungal cell membranes by preventing ergosterol growth. This interference damages fungal cells’ structural strength, making them more prone to destruction.
  • Altering Cellular Permeability: Ergosterol disruption increases fungal cell membrane permeability. As the fungal cell membrane becomes permeable, Jublia penetrates the fungal cells more easily and damages their structure.
  • Accumulation of Toxic Compounds: Efinaconazole weakens fungal cells, causing them to accumulate harmful chemicals. This poisonous build-up contributes to the general weakening of the fungus.
  • Cellular Breakdown: Ergosterol inhibition, increased permeability, and toxin buildup steadily break down fungal cells and kill the fungus.
  • Regeneration of Healthy Nails: After the fungal infection is gone, the nail can renew and return to its healthy state. Since nails grow slowly, this procedure may take months, but Jublia ensures a long-lasting cure.

Precautions and Warnings with Jublia

You can treat Jublia safely and effectively by heeding these cautions and recommendations. Visit your doctor for guidance and modifications to your therapy if you have any concerns or experience unusual side effects while going through Jublia treatment.

Just like any other pharmaceutical product, Jublia can be hazardous if not used appropriately. Before taking Jublia to treat your fungal nail infection, pay attention to these precautions and warnings to ensure your safety and maximize its efficacy.

  • Allergies: Before using Jublia, let your doctor know of any known allergies. It’s important to rule out allergens because allergic reactions can range from moderate skin irritation to severe symptoms.
  • Pregnancy and Nursing: If you’re pregnant, expecting to become pregnant, or breastfeeding, see your doctor before using Jublia. There’s little data on its safety during pregnancy and nursing, therefore, it will be important to discuss the risks and benefits with your doctor.
  • Children and the Elderly: Jublia’s safety and efficacy in youngsters and the elderly are unknown. It should be used cautiously in these age groups.
  • Proper Application: It is very important to follow doctors’ instructions on the way to use Jublia. Applying Jublia as prescribed by your doctor maximizes its efficacy and safety. It’s highly recommended to apply a small layer of the solution to the damaged nails daily.
  • Avoid Eye and Mouth Contact: Jublia is a topical medication that should only be used externally. Avoid eye and mouth contact when administering it. In case of accidental contact, rinse thoroughly with clean water.
  • Interactions with Other Drugs: You must inform your doctor of any other medications and supplements you are using. This can prevent interactions that could impact Jublia’s efficacy or safety.
  • Be persistent and patient: Good results take time. Fungal nail infections are stubborn, so it may take months of constant application to see results. Jublia should be used as directed even if results are delayed.

Jublia Side Effects

Although Jublia is typically well tolerated, some people may experience negative effects just like with any other medication.

It’s critical to keep in mind that each person’s reaction to medication may differ. Consult your healthcare practitioner if you notice any unusual or unpleasant side effects while taking Jublia. If necessary, they can make suggestions for other therapies or offer advice on how to manage these adverse effects.

In many instances, the advantages of using Jublia to successfully cure the fungal nail infection outweigh any possible negative effects. To make sure that the treatment plan satisfies your particular requirements and tolerances, you will need to collaborate with your healthcare professional.

Here is a brief list of possible side effects:

Typical Negative Effects

  • Skin Irritation: Mild skin irritation or redness at the application site is the most frequent adverse effect of Jublia. This is often short-lived and should go away as your treatment goes on.

Uncommon Side Effects

  • Blistering: Blisters may occasionally from where the application was made. If this happens, seek advice from your healthcare professional.
  • Itching or Burning Sensation: You can get a slight burning or itching sensation where Jublia has been applied. Generally, this is nothing to worry about, but if it worsens or persists, see a doctor.

Rare Side Effects

  • Allergic Reactions: Allergic Reactions are uncommon side effects. Jublia can cause serious allergic reactions which may cause a rash, itching, swelling, extreme vertigo, or breathing difficulties. Seek emergency medical help if you encounter any of these symptoms.

Drug Interactions With Jublia

Remember that this list is not exhaustive, so tell your doctor about all your medications. They can provide individualized assistance and manage any interactions to guarantee your safety and Jublia medication efficacy. Always follow your doctor’s orders and notify them of medication changes.

Jublia rarely interacts with other drugs, although a few do. You must tell your doctor about all your drugs to ensure safe and efficient treatment. Some significant interactions include the following:

  1. Blood Thinners (Anticoagulants): Warfarin and other anticoagulants may enhance bleeding or bruise risks when used with Jublia. If you take blood thinners, tell your doctor to check your clotting.
  2. Skin Products: Cosmetics or other topical treatments on treated nails may impact Jublia absorption and efficacy. Avoid using such products in the same region before or after Jublia.
  3. Medications Processed by the Liver: Some liver-processed drugs may interact with Jublia. Your doctor should know about any liver-related diseases or medications you use to determine interaction risk.

Jublia Strengths & Dosages

Effective treatment requires the use of the correct Jublia strengths available and the recommended dosages. Below are a few things you need to know about Jublia’s strengths and dosages:

Jublia Strengths

A 10% topical solution of Jublia is the only strength offered. Each milliliter of the solution at this concentration contains 100 milligrams of Efinaconazole.

Correct Dosage

Keep in mind that each person’s response to treatment may differ, and it may take several months before you notice any changes in the quality and look of your nails. Please contact your healthcare practitioner for advice and clarification if you have any questions or concerns about the strength, dosage, or application of Jublia. They can offer you individualized guidance to make sure you benefit the most from your care.

Jublia should be applied to the affected nail(s) once daily in most cases.

How to Use Jublia

For Jublia to work best in treating fungal nail infections, it must be used and applied correctly. Here is a step-by-step guide on using Jublia effectively:

Step 1:  Wash Hands

Wash your hands thoroughly with soap and water to ensure cleanliness in the first step of preparation.

Prepare your nails by, if at all possible, gently washing them with water and a little soap. Use a fresh towel to pat the area dry.

Step 2: Application

  • Open the Bottle: Remove the Jublia bottle’s cap to open it.
  • Apply a Thin Layer: Apply a thin layer of Jublia evenly to the whole surface of the damaged nail(s) using the applicator brush that is attached to the bottle cap. Pay close attention to the nail’s front, rear, and sides.
  • Allow to Dry: Give the mixture time to dry up; often takes a few minutes. Until it is completely dry, refrain from touching or covering the treated nail.

Step 3: Post Application

  • Replace the Cap: Screw the cap tightly onto the Jublia bottle.
  • Wash Your Hands Again: To get rid of any leftover medication, wash your hands thoroughly once again.

Step 4: Daily Routine

  • Consistency: Use Jublia as directed by your healthcare professional once daily, preferably at the same time every day.
  • Nail Trimming: Trimming your nails on a regular basis will assist Jublia in penetrating the nail more efficiently by removing any infected regions.
  • Be Patient: Be aware that it can take a while for the treatment to start working. Even if you don’t notice any changes right away, keep using Jublia consistently as prescribed by your doctor.
  • Follow-up Appointments: Attend any follow-up appointments arranged by your doctor to track your progress and make any required modifications to your treatment plan.

Alternatives to Jublia

Yes, various topical Jublia alternatives exist. We have two main alternatives for Jublia namely:


The Penlac nail glaze is good for both fingernails and toenails and can be used topically. Unlike Jublia, it inhibits fungus development by blocking an enzyme that provides nutrition.

Penlac is applied daily to the affected region, with every application adding an extra pharmaceutical layer. You should also rub alcohol on your nails every week to eradicate drug buildup. This process continues throughout the 48-week treatment.

According to a survey done by the National Institutes of Health (NIH), less than 40% of Penlac users tested negative for fungus after 48 weeks of administering, and total cure rates ranged from 5% to 8%. Note that Penlac and Jublia have not been compared head-to-head. Penlac is a generic choice, which may save money.


Kerydin is also an alternative to Jublia. It belongs to the class of antifungals known as oxaboroles and works by preventing the fungus from producing proteins.

Kerydin, like Jublia, is applied daily to affected toenails for 48 weeks. During a clinical study conducted by the National Library of Medicine (NLH), after 52 weeks, less than 40% of Kerydin users tested negative for fungus, with cure rates ranging from 6% to 9%. Just like Penlac, Kerydin and Jublia have not been compared head-to-head to determine their efficacy comparison.

FAQs of Jublia

If you are a current customer and have questions about Jublia, feel free to contact us and we will connect you with one of our licensed pharmacists.

How long is the treatment time of Jublia?

Depending on how severe the fungal infection is, the treatment time may change. Even if you start to feel better, it’s crucial to keep taking Jublia as prescribed by your doctor.

How do I apply Jublia?

Pay close attention to the application procedure instructions provided by your healthcare professional. Cleaning the damaged nail(s), applying a thin layer of Jublia to the entire nail surface, and letting it dry fully are the usual steps.

What happens if I miss a dose of Jublia?

Jublia works best when used consistently. To create a habit, try not to skip dosages and apply it at the same time every day.

Should I regulatory cut the infected nail while taking Jublia?

Regularly filing and cutting the afflicted nails can help Jublia work more effectively. By doing so, you decrease the fungus burden and improve the medication’s ability to permeate the nail.

What else can I do to make Jublia work better?

Keeping nails dry and clean can help your treatment go more smoothly.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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