For patients suffering from certain medical conditions, Asacol may help. A medication known as an aminosalicylate, Asacol is primarily prescribed for the treatment of inflammatory bowel diseases. Among these conditions are Crohn’s disease and ulcerative colitis, both of which have a significant impact on quality of life.

Asacol was developed to meet the specific needs of those who suffer from inflammatory bowel diseases. The Asacol product may address patients’ challenges with Crohn’s disease, ulcerative colitis, or both.

Asacol’s mechanism of action within the body provides profound insights into its effectiveness. Asacol contains mesalamine, an anti-inflammatory ingredient renowned for its effectiveness. The active component of this product plays an important role in reducing the inflammatory processes that wreak havoc on the digestive system.

After being administered, Asacol travels through the digestive system to reach the colon. It does this by strategically releasing mesalamine, which takes charge of the inflammation by calming it at its source. Asacol relieves the symptoms of excessive immune response, fostering a more comfortable and manageable daily lifestyle.

Asacol’s effectiveness has been the subject of extensive research and clinical trials. Numerous studies have demonstrated its potential to induce and maintain remission in patients with inflammatory bowel diseases. It’s not just about minimizing discomfort; Asacol strives to enhance users’ overall well-being.

This medication is available through our partnering (and verified) pharmacies in the United Kingdom, Singapore and Mauritius.

Asacol vs. Asacol MR

Asacol, a brand name for mesalamine, is a medication primarily used to treat inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease. It belongs to the class of drugs known as aminosalicylates. Asacol functions by reducing inflammation in the intestines, thereby alleviating symptoms like abdominal pain, diarrhea, and rectal bleeding.

Asacol MR, on the other hand, stands for Asacol Modified-Release. Like its counterpart, it contains mesalamine as its active ingredient. The key distinction lies in its formulation, designed to release the medication gradually over an extended period. This controlled release mechanism allows for a sustained effect and often leads to less frequent dosing compared to the regular Asacol.

Comparing Effectiveness

When comparing the effectiveness of these two variants, it’s important to note that both Asacol and Asacol MR aim to achieve the same outcome: managing the symptoms of inflammatory bowel diseases. However, the modified-release nature of Asacol MR might provide certain advantages. The gradual release of the medication can lead to a consistent therapeutic effect, potentially resulting in improved symptom control for patients.

Dosage Regimen

Asacol typically requires more frequent dosing throughout the day to maintain its therapeutic levels in the body. This can be a practical challenge for some individuals, especially those with busy schedules. Asacol MR, with its prolonged release mechanism, often demands fewer daily doses. This convenience can contribute to better adherence to the prescribed regimen.


Asacol is a renowned medication used in the treatment of inflammatory bowel diseases, such as ulcerative colitis and Crohn’s disease. Its administration involves taking multiple tablets throughout the day. The recommended dosage is usually divided into smaller portions to ensure a consistent therapeutic effect. The tablets are generally taken with meals, allowing for better absorption and reduced stomach discomfort. This dosing regimen, although effective, may require patients to remember and adhere to a specific schedule.

Asacol MR, on the other hand, offers a modified-release formulation. This means that the medication is designed to release its active ingredients gradually over an extended period. Consequently, patients need to take fewer tablets compared to the standard Asacol regimen. The modified-release feature not only simplifies the administration process but also contributes to improved patient compliance. Individuals who find it challenging to adhere to a strict dosing schedule may find Asacol MR more convenient and effective.


Asacol’s absorption primarily occurs in the colon, where it exerts its therapeutic effects. The active ingredient in Asacol is mesalamine, which is released in the colon to target the inflammation directly. This targeted approach minimizes systemic absorption, thereby reducing the likelihood of widespread side effects. The delayed release of mesalamine in the colon is facilitated by the special coating of the tablets.

Asacol MR’s absorption process aligns with its modified-release nature. The gradual release of active ingredients allows for sustained therapeutic levels in the colon. This sustained release not only enhances the efficacy of the medication but also contributes to a lower frequency of dosing. As a result, patients may experience more stable symptom control and a reduced risk of fluctuations in their condition.

Pros and Cons of Asacol


  1. Proven Efficacy: Asacol has shown remarkable efficacy in managing inflammatory bowel diseases (IBD) like ulcerative colitis. Its active ingredient, mesalamine, targets inflammation in the intestines effectively.
  2. Minimized Systemic Absorption: Asacol primarily works in the colon without significantly entering the bloodstream. This localized action reduces the likelihood of systemic side effects.
  3. Convenience: With various dosage forms available, including tablets and suppositories, patients have the flexibility to choose the most suitable option based on their preferences and condition.


  1. Limited Spectrum: Asacol’s efficacy is predominantly focused on gastrointestinal conditions, limiting its utility for individuals with other health concerns.
  2. Dosage Frequency: Depending on the severity of the condition, Asacol may require multiple daily doses, which can be inconvenient for some patients.

Pros and Cons of Asacol MR


  1. Sustained Release: Asacol MR is designed to release its active ingredient gradually, ensuring a consistent therapeutic effect over time. This can lead to better symptom management.
  2. Reduced Dosage Frequency: Due to its extended-release formulation, Asacol MR often requires fewer daily doses compared to immediate-release medications.
  3. Comprehensive Treatment: Asacol MR’s sustained action makes it a suitable choice for maintaining remission in individuals with ulcerative colitis.


  1. Onset of Action: Asacol MR’s gradual release may result in a slower onset of action compared to immediate-release medications, which could be a concern for individuals requiring rapid symptom relief.
  2. Potential for Side Effects: While the localized action minimizes systemic effects, there is still a possibility of gastrointestinal side effects, albeit at a reduced rate.

Warnings and Precautions

In the realm of medical treatment, understanding the warnings and precautions associated with medications is paramount. Asacol, a medication used for certain gastrointestinal conditions, carries its own set of precautions that must not be overlooked.

  • Consultation with a Healthcare Professional: Before embarking on any medical journey with Asacol, it’s imperative to consult a qualified healthcare professional. This medication might not be suitable for everyone, and a healthcare provider can assess your specific medical history, current health status, and any potential interactions with other medications.
  • Allergic Reactions: Boldly underscored, allergic reactions to Asacol have been reported, although they are rare. If you experience symptoms such as difficulty breathing, hives, swelling of the face or throat, it’s crucial to seek immediate medical attention. Do not ignore any signs of an allergic reaction.
  • Existing Medical Conditions: Individuals with a history of kidney problems should exercise caution while using Asacol. Prior medical conditions must be discussed openly with your healthcare provider, ensuring that the medication is suitable and safe for your specific health circumstances.
  • Pregnancy and Breastfeeding: For expectant mothers and those who are breastfeeding, a thoughtful conversation with a healthcare professional becomes even more critical. The potential risks and benefits of using Asacol during these periods should be carefully evaluated.
  • Monitoring Blood Tests: Regular monitoring through blood tests may be required during the course of Asacol treatment. This is particularly important to ensure that the medication is not adversely affecting your body’s functions.
  • Interactions with Other Medications: Highlighting the significance of transparency, it’s essential to inform your healthcare provider about all medications you are currently taking. Asacol might interact with other drugs, potentially leading to complications or reduced effectiveness.
  • Dosage Adherence: Adhering strictly to the prescribed dosage is non-negotiable. Altering the dosage without professional guidance can lead to suboptimal results or adverse effects.
  • Side Effects Management: While Asacol aims to improve your health, it’s not uncommon to experience side effects. These can range from mild to severe, and promptly communicating any unusual symptoms to your healthcare provider is crucial for managing your well-being.
  • Pediatric Use: For the pediatric population, the usage of Asacol requires specific considerations. Only under the guidance of a qualified pediatrician should this medication be administered to children.
  • Storage and Disposal: Concluding with practicality, proper storage and disposal of Asacol are important factors. Keep the medication away from excessive heat or moisture, and when it’s no longer needed or has expired, dispose of it in accordance with recommended guidelines.

Side Effects

In the realm of gastrointestinal health, Asacol has emerged as a widely used medication. However, like any medicinal intervention, it comes with a spectrum of potential side effects.

Common Side Effects

  • Gastrointestinal Distress: Some individuals may encounter mild stomach discomfort, bloating, or flatulence. These symptoms usually fade away as treatment progresses.
  • Headache: Occasionally, patients might experience mild headaches during the initial stages of Asacol usage. Staying hydrated and maintaining a balanced diet can alleviate this effect.
  • Nausea: A transient feeling of queasiness can be observed in some cases. Taking Asacol with food can help minimize this sensation.

Rare Side Effects

  • Allergic Reactions: In isolated instances, allergic reactions such as skin rashes, itching, or swelling might occur. If these symptoms manifest, seeking medical attention is crucial.
  • Liver Function Changes: Some individuals may experience alterations in liver enzyme levels. Regular medical check-ups can monitor these changes effectively.
  • Blood Disorders: Rarely, Asacol could lead to changes in blood cell counts. It’s imperative to report any unusual bruising or bleeding to a healthcare professional promptly.

Severe Side Effects

  • Pancreatitis: A severe inflammation of the pancreas, though rare, has been associated with Asacol usage. Abdominal pain, persistent nausea, and vomiting warrant immediate medical attention.
  • Kidney Problems: Individuals might encounter changes in urine patterns or swelling due to kidney complications. Swift medical intervention can prevent further exacerbation.
  • Pericarditis: In extremely rare cases, Asacol usage has been linked to pericarditis, an inflammation of the heart lining. Symptoms include chest pain and difficulty breathing, necessitating urgent medical care.


When it comes to medication, understanding how a drug interacts with other substances is crucial to ensure both its effectiveness and your safety. Asacol is no exception.

Drug Interactions

  1. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): While Asacol primarily targets the digestive system, combining it with NSAIDs could amplify the risk of gastrointestinal side effects.
  2. Immunosuppressants: Caution is advised when taking immunosuppressive medications alongside Asacol, as this combination might compromise the immune response.
  3. Blood Thinners: Interactions between Asacol and blood-thinning drugs can potentially heighten the risk of bleeding. Medical supervision is crucial if these medications coexist.

Herbal Interactions 

  1. Aloe Vera: This widely used herb with potential anti-inflammatory properties might accentuate Asacol’s effects. Consultation with a healthcare professional is recommended.
  2. Garlic: Known for its cardiovascular benefits, garlic’s blood-thinning tendencies could synergize with Asacol, leading to unintended outcomes. Expert advice should be sought.
  3. Ginseng: Ginseng’s potential to boost immune function might interact unpredictably with Asacol’s actions. Prior medical assessment is advisable.

Food Interactions

  1. Dairy Products: While Asacol doesn’t exhibit major interactions with food, dairy might hinder its absorption. Administering the medication away from dairy consumption could optimize its effects.
  2. High-Fiber Foods: Fiber-rich meals could potentially influence Asacol’s release and absorption. Maintaining a consistent dietary pattern can aid in avoiding fluctuations.
  3. Grapefruit: Known to impede the metabolism of certain drugs, grapefruit might not significantly impact Asacol. Regardless, moderation is key.


When it comes to managing your health, understanding the dosing guidelines for medications is crucial. Asacol is a medication that’s widely prescribed for certain gastrointestinal conditions. To ensure the best results and minimize the risk of any adverse effects, it’s important to follow the dosing guidelines precisely.

Initial Dosing

The initial dosing of Asacol sets the tone for your treatment journey. It’s the first step towards managing your condition effectively. The standard initial dose of Asacol for adults is usually 800 mg three times a day. This dosage helps to swiftly address the symptoms and start the healing process. Your healthcare provider might adjust this initial dosage based on the severity of your condition and your individual response to the medication. It’s crucial to follow your healthcare provider’s recommendations closely.

Maintenance Dosing

After the initial phase, your healthcare provider will likely recommend a maintenance dose of Asacol. The purpose of maintenance dosing is to sustain remission and prevent the recurrence of symptoms. In most cases, the maintenance dose of Asacol is 1.6 g per day, divided into two doses. This lower dosage is effective in keeping your condition under control while reducing the risk of potential side effects. Adhering to your prescribed maintenance dose is key to long-term success.

Missed Dose

Life can get busy, and it’s possible to forget a dose of Asacol. If you miss a dose, the recommended course of action is to take it as soon as you remember, unless it’s close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. It’s important not to double up on doses to make up for the missed one, as this can lead to unwanted side effects. If you’re unsure about what to do, consulting your healthcare provider is always a good idea.


While adhering to the prescribed dosing guidelines is crucial, it’s also important to be aware of the risks associated with an overdose. Taking more than the recommended dose of Asacol can lead to serious health complications. If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose can include severe nausea, vomiting, confusion, and even unconsciousness. It’s better to be cautious and seek help if you’re concerned about a potential overdose.


Proper storage preserves the medication’s integrity, potency, and safety.

  • Temperature Control: Store Asacol at room temperature, ideally between 68°F and 77°F (20°C – 25°C). Avoid exposing it to extreme temperatures, such as direct sunlight, heat sources, or freezing conditions, as this can compromise the medication’s integrity.
  • Original Packaging: Keep Asacol in its original packaging, ensuring it remains in the blister packs or bottles provided by the manufacturer. This packaging is designed to protect the medication from environmental factors and maintain its potency.
  • Moisture Prevention: Protect the medication from moisture by storing it in a dry place. Bathrooms and kitchens, where humidity levels can be high, should be avoided. A cool, dry cabinet or drawer is an excellent choice for storage.
  • Avoiding Air Exposure: Minimize air exposure by sealing the packaging tightly after each use. This prevents unnecessary contact with air, which can degrade the medication over time.
  • Childproof Storage: If you have children at home, store Asacol out of their reach. Consider using childproof containers or placing the medication in a locked cabinet to ensure their safety.
  • Away from Pets: Just like with children, ensure that pets cannot access the medication. Some pets might be curious and chew on containers, leading to potential ingestion or damage.

IMPORTANT NOTE: The information provided here is for educational purposes only and is not intended to serve as medical advice, diagnosis, or treatment recommendations. It should not be taken as an endorsement of any specific medication or treatment. Individual health conditions and responses to treatment can vary greatly; therefore, this information should not be seen as a guarantee of safety, suitability, or effectiveness for any particular individual. Always consult with a healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment plans.

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